In this paper, we consider a 5D quadratic nonlinear Schrodinger system: iu(t) + Delta u = -2v (u) over bar, iv(t) + k Delta v = -u(2), and (t, x) is an element of R x R-5, k > 0. If k=1/2, we say the system satisfies the mass-resonance condition. Using the argument of Dodson and Murphy [Math. Res. Lett. 25, 1805 (2018)], we prove that the solution (u.v) scatters if initial data (u(0), v(0)) is an element of H-1(R-5) x H-1(R-5) satisfy E(u(0), v(0))M(u(0), v(0)) < E(Q(1), Q(2))M(Q(1), Q(2)) and K(u(0), v(0))M(u(0), v(0)) < K(Q(1), Q(2))M(Q(1), Q(2)) and k lies in some small neighborhood of 1/2....