Entities and relations extraction are the key tasks in the construction of biomedical knowledge graph, which play an important role in the biomedical artificial intelligence. However, extraction of entities and relations from biomedical texts is challenging because of the overlapping triples problem. The previous approaches typically divided the task into two separate sub-tasks. However, these methods failed to address the error propagation problem. Recent methods have been proposed to perform both sub-tasks simultaneously. Nonetheless, most current methods still encounter issues related to im...