关键词：
surface-enhanced Raman spectra;anticancer model drugs;N-D-glucosamine;beta-naphthaldehyde and glycine
摘要：
Copper(II), zinc(II), cobalt(II) and cobalt(III) complexes of N-D-glucosamine β-naphthaldehyde (C<inf>17</inf>H<inf>19</inf>O<inf>6</inf>N, NG) and glycine were synthesized. The four novel metal complexes, Cu(II)C<inf>19</inf>H<inf>28</inf>O<inf>11</inf>N<inf>2</inf>(CuGNG), Zn(II)C<inf>19</inf>H<inf>24</inf>O<inf>9</inf>N<inf>2</inf>(ZnGNG), Co(II)C<inf>19</inf>H<inf>28</inf>O<inf>11</inf>N<inf>2</inf>(Co(II)GNG) and Co(III)C<inf>21</inf>H<inf>29</inf>O<inf>12</inf>N<inf>2</inf>(Co(III)GNG) were characterized by means of infrared (IR), electronic absorption spectroscopy and NMR etc. The surface-enhanced Raman spectra of the four complexes and their interaction with DNA were studied. By comparison of the surface-enhanced Raman spectra (SERS), the information of the four complexes' SER active sites and adsorption orientation were obtained. Combined with fluorescence spectra of Ethidium bromide (EthBr) DNA system, we concluded that none of the four complexes intercalate into DNA and that the presence of the glycine ligand lowered the anticancer activity of NG series complexes.
摘要：
Aromatic-substituted derivatives of 1,3,2-diazaphospholidin-4-ones 2a-g were readily prepared front 1,3-diaryl glycinamides 1 by the reaction with hexaethylphosphoric triamide. Their chemical transformation was selectively effected with different thionation reagents to afford thionated products at the phosphorus atom to give 3a-g and at the carbonyl group to give 4a. An oxidation reaction at phosphorus to produce 5a was effected with 10% hydrogen peroxide. Preliminary bioassays revealed that some of the title compounds, 2a-g and 3a-g, possess selective herbicidal activity against rape. (C) 2001 John Wiley & Sons, Inc.
作者机构：
[Tong, Z; Xin, Y; Guanghan, L] Cent China Normal Univ, Dept Chem, Wuhan 430079, Peoples R China.
通讯机构：
[Guanghan, L] C;Cent China Normal Univ, Dept Chem, Wuhan 430079, Peoples R China.
关键词：
Alcohol;Pencil lead;SPME;Water
摘要：
In order to conquer the shortcomings of commercial SPME coatings: they can't stand high temperature, are easy to drop off, the longevity of usage is short and they are too expensive, we used pencil lead as a new sorbent to analyze the alcohol in water. The linear range is 5 × 10-6-2.5 × 10-8g/mL. The detection limit is 5 × 10-9g/mL. We also used this method to determine the concentration of alcohol in environment water. The recoveries are 107.5% and 97%. The RSD is 5.9%. Hence the pencil lead is a very good material for solid-phase microextraction (SPME).
摘要：
In order to search for novel fungicides with high activity, a series of 2-heteroaryl-4-chromanones were designed and synthesized via bioisosterism substitution. The structures of all new compounds were confirmed by spectroscopic methods and microanalyses. Preliminary bioassays indicated that some compounds showed fungicidal activity against Rhizoctonia solani, Fusarium oxysporum, Physalospora piricola and Cercospora beticola.
作者机构：
[Zhu, CF; Yang, SJ; Xu, HH] Cent China Normal Univ, Dept Chem, Wuhan 430079, Peoples R China.
关键词：
p, p '-Diaminodiphenylmethane;Schiff bases;thermochromic;sulphonamide
摘要：
p, p -Diaminodiphenylmethane-Schiff bases (SB) of general formula (R)-phCH=N-ph-CH2-ph-N=CHph(R), where R is p-NO2, m-NO2, p-OH, o-OH, p-CI, -H, p-OCH3, and sulphonamide Schiff bases (SB) of general formula (R)-phCH=N-ph-SO2NH2, where R is p-NO2, m-NO2, p-OH, o-OH, p-Cl, -H, p-OCH3, were synthesized and their structure have been characterized by the melting pointing, (HNMR)-H-1, MS, and elemental analysis. They are thermolabile and undergo thermo-chromism and thermal decomposition after melting. The TG. and DSC measurement were recorded in dynamic air and interpreted.
摘要：
The binding site of Fe3+ in the purine base of adenosine 5'-triphosphate (ATP) was studied by nuclear magnetic resonance (NMR). The NMR relaxation rates (R-1) of H-1 and P-31 in ATP solutions free of and containing ferric ions were measured in the pH range of 3-10. It was found that Fe3+ selectively enhanced the relaxation rate of protons. In the presence of Fe3+, the R-1 of H2 was much bigger than that of H8 at a lower pH (3-4.5), while at a higher pH (5.5-7.5) the R-1 of H8 was more enhanced than H2. At a pH of around 5, both H2 and H8, as well as all three phosphorous, showed a sudden jump in R-1. When pH>8, Fe3+ failed to show appreciable enhancement of R-1 to all protons and phosphorous. The quantitative data of relaxation rate enhancements suggest that the binding site of Fe in ATP is strongly dependent on pH. At lower pH values, Fe3+ binds N1 but at higher pH it binds to N7. When pH is around 5, the whole purine base donates the aromatic pi -electrons to the ferric ion, forming a ferrocene-like complex, while when pH>8, ATP could not form complexes with Fe3+. (C) 2001 Elsevier Science B.V. All rights reserved. [References: 18]
作者机构：
[Xu, ZF; Wu, TJ; Liu, ZJ; Ding, MW] Cent China Normal Univ, Inst Organ Synth, Wuhan 430079, Peoples R China.
通讯机构：
[Ding, MW] C;Cent China Normal Univ, Inst Organ Synth, Wuhan 430079, Peoples R China.
摘要：
The carbodiimides 2, obtained from aza-Wittig reactions of vinylimino-phosphorane 1 with aromatic isocyanates, reacted with aliphatic primary amines to give mainly 2-alkylamino-4H-imidazolin-4-ones 4 with unusual selectivity.
期刊：
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS,2000年156(1):9-20 ISSN：1042-6507
通讯作者：
Huang, TB
作者机构：
E China Univ Sci & Technol, Inst Pesticides & Pharmaceut, Shanghai 200237, Peoples R China.;Cent China Normal Univ, Inst Organ Synth, Wuhan 430079, Peoples R China.;[Huang, TB] E China Univ Sci & Technol, Inst Pesticides & Pharmaceut, POB 544, Shanghai 200237, Peoples R China.
通讯机构：
[Huang, TB] E;E China Univ Sci & Technol, Inst Pesticides & Pharmaceut, POB 544, Shanghai 200237, Peoples R China.
摘要：
Two new heterocyclic thiophosphoryl chlorides (2), derivatives of 1,3,2-benzodiazaphosphole, are synthesized. The reaction of respective thiophospboryl chlorides (1) and (2) with AlCl3 affords dimeric heterocyclic diphosphonium dications 3 and 4. The reaction of 2a with CF3SO3Ag gives rise to dimeric anhydride 5 instead of the expected lambda(5)sigma(3)-thiophosphoryl cations. The results show that lambda(5)sigma(3)-thiophosphonium cations incorporated into a thiadiaza-phospholic system (1) or benzodiazaphospholic system (2) are not stable, and undergo a structural rearrangement to give a lambda(4)sigma(4)-phosphorus-centre products.
摘要：
The solid-state coordination reaction of CuCl2. 2H(2)O with 8-hydroxyquinoline (HQ): HQ(s)+CuCl2. 2H(2)O(s)--> Cu(HQ)Cl-2(s)+2H(2)O(l) has been studied by solution calorimetry. The molar dissolution enthalpies of the reactants and the products in 3 mol l(-1) HCl of the solid-solid coordination reaction have been measured using an isoperibol calorimeter. From the results and other auxiliary quantities, the standard molar formation enthalpy of [Cu(HQ)Cl-2,s,298.15 K] at 298.15 K has been derived: Delta(f)H(m)(Theta)(Cu(HQ)Cl-2,s,298.15 K)=-340.12 kJ mol(-1). (C) 2000 Elsevier Science B.V. All rights reserved.
