1-（嘧啶基-4）-3-（2，6-二氟苯甲酰基）脲衍生物的合成与生物活性
作者：
Wei, Zhen-Zhong* ;Pang, Huai-Lin;Liu, Ai-Ping;Hua, Cheng;Lin, Li-Zhi;...
期刊：
有机化学 ,2006年26(8):1120-1124 ISSN：0253-2786
通讯作者：
Wei, Zhen-Zhong
作者机构：
[Wei, Zhen-Zhong] Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China.;Natl Pesticide Res & Dev S Ctr, Hunan Res Inst Chem Ind, Hunan Branch, Changsha 410007, Peoples R China.;Hunan Normal Univ, Coll Chem & Chem Engn, Changsha 410081, Peoples R China.
通讯机构：
[Wei, Zhen-Zhong] C;Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China.
关键词：
苯甲酰脲;嘧啶;合成;生物活性
摘要：
为了寻找高效、低毒、低残留的环境友好杀虫剂，设计并合成了12个新的1-（嘧啶基-4）-3-（2，6-二氟苯甲酰基）脲衍生物6a-61，其结构经IR，^1H NMR，LC／MS和元素分析确证．初步生物活性测试结果表明，部分化合物具有明显的杀虫活性，如6g在100mg／L浓度下，对粘虫（Mythimna sepatara）具有100％的杀虫活性
语种：
中文
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Development of a general quantum-chemical descriptor for steric effects: Density functional theory based QSAR study of herbicidal sulfonylurea analogues
作者：
Xi, Zhen
* ;Yu, Zhihong;Niu, Zongwei;Ban, Shurong;Yang, Guangfu
（ 期刊：
Journal of Computational Chemistry ,2006年27(13):1571-1576 ISSN：0192-8651
通讯作者：
Xi, Zhen
作者机构：
[Xi, Zhen] Nankai Univ, State Key Lab Elementoorgan Chem, Tianjin 300071, Peoples R China.;Nankai Univ, Dept Biol Chem, Tianjin 300071, Peoples R China.;Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China.
通讯机构：
[Xi, Zhen] N;Nankai Univ, State Key Lab Elementoorgan Chem, Tianjin 300071, Peoples R China.
关键词：
quantum-chemical descriptor;density functional theory;QSAR;sulfonylurea herbicide;acetohydroxyacid synthase
摘要：
Quantitative structure‐activity relationship (QSAR) analysis has become one of the most effective approaches for optimizing lead compounds and designing new drugs. Although large number of quantum‐chemical descriptors were defined and applied successfully, it is still a big challenge to develop a general quantum‐chemical descriptor describing the bulk effects more directly and effectively. In this article, we defined a general quantum‐chemical descriptor by characterizing the volume of electron cloud for specific substituent using the method of density functional theory. The application of our defined steric descriptors in the QSAR analysis of sulfonylurea analogues resulted in four QSAR models with high quality (the best model: q2 = 0.881, r2 = 0.901, n = 35, s = 0.401, F = 68.44), which indicated that this descriptor may provide an effective way for solving the problem how to directly describe steric effect in quantum chemistry‐based QSAR studies. © 2006 Wiley Periodicals, Inc. J Comput Chem 27: 1571–1576, 2006
语种：
英文
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1,2,4,5-Tetrakis(bromomethyl)benzene
作者：
Wang, Zhi-Guo* ;Wang, Yu-Zhou;She, Neng-Fang;Gao, Meng
期刊：
ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY ,2006年62(11):o5106-o5107 ISSN：2053-2296
通讯作者：
Wang, Zhi-Guo
作者机构：
[Wang, Zhi-Guo; Gao, Meng; She, Neng-Fang; Wang, Yu-Zhou] Cent China Normal Univ, Minist Educ, Coll Chem, Key Lab Pesticides & Chem Biol, Wuhan 430079, Peoples R China.
通讯机构：
[Wang, Zhi-Guo] C;Cent China Normal Univ, Minist Educ, Coll Chem, Key Lab Pesticides & Chem Biol, Wuhan 430079, Peoples R China.
摘要：
The title molecule, C10H10Br4, lies on a crystallographic inversion center which is located at the center of the benzene ring. The crystal structure is stabilized by intermolecular Br⋯Br and C—H⋯Br interactions.
语种：
英文
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拓扑异构体的研究（Ⅰ）——C型与S型拓扑异构体的波谱性质及结构鉴定
作者：
Zhou, BH;Yin, GD;Liu, XP;Wu, AX*
期刊：
高等学校化学学报 ,2006年27(1):58-61 ISSN：0251-0790
通讯作者：
Wu, AX
作者机构：
[Wu, AX] Cent China Normal Univ, Key Lab Pesticide & Chem Biol, Minist Educ, Dept Chem, Wuhan 430079, Peoples R China.;Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China.
通讯机构：
[Wu, AX] C;Cent China Normal Univ, Key Lab Pesticide & Chem Biol, Minist Educ, Dept Chem, Wuhan 430079, Peoples R China.
关键词：
合成;拓扑异构体;结构分析;波谱性质
摘要：
利用^1H和^13CNMR，IR，UV，SEM对合成的4种C型和S型拓扑异构体进行了结构表征和分析，发现对于不同拓扑结构的C型和S型分子可以通过^1H NMR来鉴别，而对于相同拓扑结构的S型cis（SC）和trans（ST）分子，C型cis（CC）和trans（CT）分子则要结合^13C NMR来鉴别．四种拓扑异构体的IR、UV、波谱性质以及SEM图象没有显著的差异．
语种：
中文
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N-[(3RS)-3-(4-Chlorophenyl)heptanoyl]bornane-10,2-sultam
作者：
Cao, XF;Yin, J;Yu, GA;Liu, SH*
期刊：
ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY ,2006年62(1):o241-o242 ISSN：2053-2296
通讯作者：
Liu, SH
作者机构：
[Yin, J; Liu, SH; Cao, XF; Yu, GA] Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticides & Chem Biol, Wuhan 430079, Peoples R China.
通讯机构：
[Liu, SH] C;Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticides & Chem Biol, Wuhan 430079, Peoples R China.
摘要：
In the title compound, C23H32ClNO3S, molecules are linked via C—H⋯N/O interactions, forming two-dimensional sheets parallel to the (100) plane.
语种：
英文
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Synthesis and Crystal Structure of [CpRu(η_5-C_5H_5)(dppc)Cl][PF_6]
作者：
Wu Xiang-Hua;Yu Guang-Ao* ;Meng Xiang-Gao;Chen Yan;Ren Yong;...
期刊：
Chinese Journal of Structural Chemistry ,2006年25(12):1471-1474 ISSN：0254-5861
通讯作者：
Yu Guang-Ao
作者机构：
[Meng Xiang-Gao; Yu Guang-Ao; Ren Yong; Wu Xiang-Hua; Liu Sheng-Hua; Chen Yan; Yu, GA] Cent China Normal Univ, Coll Chem, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China.
通讯机构：
[Yu Guang-Ao] C;Cent China Normal Univ, Coll Chem, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China.
关键词：
ruthenium;1,1'-bis(diphenylphosphino)cobaltocenium hexafluorophospate;crystal structure
摘要：
The title complex [Ru(η_5-C_5H_5)(dppc)Cl][PF_6] has been synthesized by the reaction of [Ru(η_5-C_5H_5)(PPh_3)_2Cl] with [dppc][PF_6] (1,1'-bis(diphenylphosphino)cobaltocenium hexaflurophospate) in CH_2Cl_2, and its crystal structure was determined by single-crystal X-ray diffraction analysis. It crystallizes in monoclinic, space group P2_1/n with a = 15.754(8), b =13.704(7), c=19.120(10) (A),β=106.148(9)°, V=3965(4) (A)3, Z=4, C_(40)H_(35)Cl_3CoF_6P_3Ru, Mr=988.94, D_c=1.657 g/cm~3, F(000) = 1984 and μ(MoKα) = 1.181 mm~(-1). The final R = 0.0425 and wR = 0.1001 for 7002 independent reflections. The title complex shows a mononuclear Ru(Ⅱ)capped by an η_5-Cp ring, a chelating η_2-dppc and a terminal chloride to assume a three-legged piano-stool configuration.
语种：
英文
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(-)-N-[(3S)-3-(4-fluorophenyl-4-methyl)hexanoyl]bornane-10,2-sultam
作者：
Cao, Xiu-Fang;Yu, Guang-Ao;Liu, Sheng-Hua* ;Meng, Xiang-Gao
期刊：
ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY ,2006年62(10):o4458-o4459 ISSN：2053-2296
通讯作者：
Liu, Sheng-Hua
作者机构：
[Meng, Xiang-Gao; Liu, Sheng-Hua; Cao, Xiu-Fang; Yu, Guang-Ao] Cent China Normal Univ, Minist Educ, Coll Chem, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China.
通讯机构：
[Liu, Sheng-Hua] C;Cent China Normal Univ, Minist Educ, Coll Chem, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China.
摘要：
In the title compound, C 22 H 30 FNO 3 S, molecules are linked via C-H⋯O interactions. © 2006 International Union of Crystallography. All rights reserved.
语种：
英文
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Chloro[(di-tert-butylphosphino)cobalto-cenium-κP]gold(I) hexafluorophosphate
作者：
Li, LY;Ren, Y;Yu, GA* ;Liu, SH
期刊：
ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY ,2006年62(2):m249-m250 ISSN：2053-2296
通讯作者：
Yu, GA
作者机构：
[Li, LY; Ren, Y; Liu, SH; Yu, GA] Cent China Normal Univ, Key Lab Pesticides & Chem Biol, Minist Educ, Coll Chem, Wuhan 430079, Peoples R China.
通讯机构：
[Yu, GA] C;Cent China Normal Univ, Key Lab Pesticides & Chem Biol, Minist Educ, Coll Chem, Wuhan 430079, Peoples R China.
摘要：
In the crystal structure of the title compound, [AuCl{Co-(C 5H5)(C5H4PtBu 2)}]PF6 or [AuCo(C5H5)(C 13H22P)Cl]PF6, hexafluorophosphate is an uncoordinated anion. The structure contains η5~-(C 5H5C-H⋯F hydrogen bonds. © 2006 International Union of Crystallography All rights reserved.
语种：
英文
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(+)-N-[(3S)-3-(2,4-dichlorophenyl-4-methyl)-pentanoyl]bornane-10,2-sultam
作者：
Cao, Xiu-Fang;Yu, Guang-Ao* ;Lu, Wen-Chang;Meng, Xiang-Gao;Liu, Sheng-Hua
期刊：
ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY ,2006年62(7):o3069-o3070 ISSN：2053-2296
通讯作者：
Yu, Guang-Ao
作者机构：
[Meng, Xiang-Gao; Liu, Sheng-Hua; Yu, Guang-Ao; Cao, Xiu-Fang; Lu, Wen-Chang; Yu, GA] Cent China Normal Univ, Key Lab Pesticides & Chem Biol, Minist Educ, Coll Chem, Wuhan 430079, Peoples R China.
通讯机构：
[Yu, Guang-Ao] C;Cent China Normal Univ, Key Lab Pesticides & Chem Biol, Minist Educ, Coll Chem, Wuhan 430079, Peoples R China.
摘要：
In the crystal structure of the title compound, C22H 29Cl2NO3S, molecules are linked via C-H⋯O interactions, forming chains along the a axis. © 2006 International Union of Crystallography. All rights reserved.
语种：
英文
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具有光致变色性能的二芳基乙烯类大环化合物的合成及性质
作者：
尹军;余广鳌;刘盛华
作者机构：
[尹军; 余广鳌; 刘盛华] 华中师范大学化学学院农药与化学生物学教育部重点实验室
会议名称：
中国化学会全国第十三届大环化学暨第五届超分子化学学术讨论会
会议时间：
2006-08
会议地点：
中国河南洛阳
关键词：
光致变色;二芳基乙烯;大环化合物
摘要：
采用一锅合成法合成了第一个具有空腔的二芳基乙烯类大环化合物,测定了其光致变色的性质。
语种：
中文
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5-Methyl-2-morpholino-3-p-tolyl-8,9,10,11-tetra-hydro-2- benzothieno[2′,3′:6,5]pyrido[4,3-d]-pyrimidin-4(3H)-one
作者：
Chen, HL;He, HW*
期刊：
ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY ,2006年62(4):o1226-o1227 ISSN：2053-2296
通讯作者：
He, HW
作者机构：
[He, HW; Chen, HL] Cent China Normal Univ, Coll Chem, Key Lab Pesticides & Chem Biol, Wuhan 430079, Peoples R China.
通讯机构：
[He, HW] C;Cent China Normal Univ, Coll Chem, Key Lab Pesticides & Chem Biol, Wuhan 430079, Peoples R China.
摘要：
In the title compound, C25H26N4O 2S, the central tricyclic system is essentially planar. The crystal stacking is governed mainly due to π-π interactions. © 2006 International Union of Crystallography All rights reserved.
语种：
英文
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2-(3,5-Difluorophenoxy)-5-methyl-3-phenyl-8,9,10,11-tetrahydro-4H-benzo[4', 5']thieno-[3',2':5,6]pyrido[4,3-d]pyrimidin-4(3H)-one
作者：
Ren, Qing-Yun;He, Hong-Wu* ;Meng, Xiang-Gao
期刊：
ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY ,2006年62(11):o5029-o5031 ISSN：2053-2296
通讯作者：
He, Hong-Wu
作者机构：
[He, Hong-Wu; Meng, Xiang-Gao; Ren, Qing-Yun] Cent China Normal Univ, Coll Chem, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China.
通讯机构：
[He, Hong-Wu] C;Cent China Normal Univ, Coll Chem, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China.
摘要：
The asymmetric unit of the title compound, C26H19F2N3O2S, contains two independent molecules. In one of the independent molecules, the cyclohexene ring adopts a half-chair conformation, while in the other it is in an envelope conformation. In both molecules, the thiatriazacyclopenta[a]naphthalen-6-one ring system is approximately planar.
语种：
英文
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Synthesis of derivatives of pyrido[4,3-d]pyrimidin-4(3H)-one via an iminophosphorane
作者：
Liu, Jian-Chao;He, Hong-Wu* ;Ren, Qing-Yun;Ding, Ming-Wu
期刊：
Helvetica Chimica Acta ,2006年89(7):1337-1343 ISSN：0018-019X
通讯作者：
He, Hong-Wu
作者机构：
[He, Hong-Wu; Ren, Qing-Yun; Liu, Jian-Chao; Ding, Ming-Wu] Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China.
通讯机构：
[He, Hong-Wu] C;Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China.
关键词：
Iminophosphorane;Carbodiimide;Pyrido[4;3‐d]pyrimidin‐4(3H)‐ones;Aza‐Wittig reaction
摘要：
A series of new, 2-substituted 3-aryl-8,9,10,11-tetrahydro-5-methyl[1] benzothieno[3′,2′:5,6]pyrido[4,3-d]pyrimidin-4(3H)-ones, compounds 5a-q, were designed and synthesized via the aza-Wittig reaction as the key step. The iminophosphorane 1 reacted with phenyl isocyanate (or 4-chlorophenyl isocyanate) to the carbodiimide 4, which was cyclized to 5 upon addition of different amines, EtOH, or phenols in the presence of a catalytic amount of EtONa or K2CO3 (Schemes 1 and 2). The structures of compounds 5 were confirmed by IR, 1H- and 13C-NMR, EI-MS, elemental analyses, and, in the case of 51, by single-crystal X-ray diffraction (Figure). © 2006 Verlag Helvetica Chimica Acta AG.
语种：
英文
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2-(4-Chlorophenoxy)-3-isopropyl-5,6,7,8-tetrahydro-2-benzothieno[2,3-d] pyrimidin-4(3H)-one
作者：
Zeng, XH;Ding, MW* ;He, HW
期刊：
ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY ,2006年62(2):o731-o732 ISSN：2053-2296
通讯作者：
Ding, MW
作者机构：
[He, HW; Zeng, XH; Ding, MW] Cent China Normal Univ, Key Lab Pesticides & Chem Biol, Minist Educ, Coll Chem, Wuhan 430079, Peoples R China.
通讯机构：
[Ding, MW] C;Cent China Normal Univ, Key Lab Pesticides & Chem Biol, Minist Educ, Coll Chem, Wuhan 430079, Peoples R China.
摘要：
In the title compound, C19H19ClN2O 2S, the thiophene and pyrimidine rings are almost coplanar. Intramolecular C - H⋯O hydrogen bonds stabilize the molecular structure. The crystal packing is determined by van der Waals forces. No intermolecular hydrogen bonding interactions or π-π stacking interactions are present in the crystal structure. © 2006 International Union of Crystallography All rights reserved.
语种：
英文
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2-(4-Methoxyphenoxy)-1,9-diphenyl-1,9-dihydropurin-6-one
作者：
Huang, NY;Ding, MW* ;Luo, ZG;Zuo, N;Zeng, XH;...
期刊：
ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY ,2006年62(3):o1022-o1024 ISSN：2053-2296
通讯作者：
Ding, MW
作者机构：
[Ding, MW] Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticides & Chem Biol, Wuhan 430079, Peoples R China.;Cent China Normal Univ, Coll Chem, Wuhan 430079, Peoples R China.
通讯机构：
[Ding, MW] C;Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticides & Chem Biol, Wuhan 430079, Peoples R China.
摘要：
The title compound, C24H18N4O3, has a planar bicyclic imidazolo[5,4-d]pyrimidine core. The planes of the phenyl and methoxyphenoxy substituents form substantial (>30°) dihedral angles with the imidazolopyrimidine plane. Inter-molecular C - H⋯O interactions link the molecules into infinite chains running along the a axis of the crystal structure. © 2006 International Union of Crystallography All rights reserved.
语种：
英文
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具有生物活性的α-(取代苯氧乙酰氧基)烃基(次)膦酸酯的研究与开发
作者：
贺红武
作者机构：
[贺红武] 华中师范大学化学学院教育部农药与化学生物学重点实验室农药化学研究所
会议名称：
第七届全国磷化学化工暨第四届海峡化学生物学、生物技术与医药发展讨论会
会议时间：
2006-04
会议地点：
中国河南郑州
摘要：
<正>大量研究结果表明膦酸衍生物是一类具有开发潜力的活性物质,为了获得具有农药活性的膦酸衍生物,为创制新靶标新结构的农药品种提供科学依据,本课题组在前期开展了对α-氧代膦酸衍生物性的系统研究。设计合成了13系列新型的芳(杂环)氧基烃基膦酸衍生物,发现了以丙酮酸脱氢酶系为靶标的-取代苯氧基乙酰氧基烃基(次)膦酸酯类化合物,近几年本研究重点选择取代苯氧乙酰氧基烃基膦酸酯(Ⅰ)为先导体,设计合成了多系列
语种：
中文
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丙酮酸脱氢酶系抑制剂-O,O-二烷基α-氧代烃基膦酸酯类化合物的定量构效关系研究
作者：
陈婷;贺红武
作者机构：
[陈婷; 贺红武] 华中师范大学化学学院教育部农药与化学生物学重点实验室农药化学研究所
会议名称：
第七届全国磷化学化工暨第四届海峡化学生物学、生物技术与医药发展讨论会
会议时间：
2006-04
会议地点：
中国河南郑州
会议论文集名称：
第七届全国磷化学化工暨第四届海峡化学生物学、生物技术与医药发展讨论会论文集
摘要：
<正>α-氧代烃基膦酸酯(盐)类化合物是本课题组在前期研究中发现的一类具有良好除草活性的化合物。初步的生化实验表明,该类化合物为植物体内的重要代谢酶丙酮酸脱氢酶系的抑制剂。为了进一步明确影响除草活性的主要因素,利用Tripos公司的Sybyl软件,采用比较分子场分析(CoMFA)及比较分子相似性指数分析 (CoMSIA)方法,从三维空间上对本课题组前期研究中合成的32个O,O-二烷基α-氧代烃基膦
语种：
中文
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[3,5-dibromosalicylaldehyde (2-hydroxybenzoyl)-hydrazonato- κ3O,N,O′]bis(pyridine-κN)zinc(II)
作者：
Wu, Y;Shi, SM;Jia, B;Hu, ZQ*
期刊：
ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY ,2006年62(3):m648-m649 ISSN：2053-2296
通讯作者：
Hu, ZQ
作者机构：
[Hu, ZQ] Cent China Normal Univ, Dept Chem, Wuhan 430079, Hubei, Peoples R China.;Sichuan Univ Sci & Technol, Dept Chem, Sichuan 643000, Peoples R China.
通讯机构：
[Hu, ZQ] C;Cent China Normal Univ, Dept Chem, Wuhan 430079, Hubei, Peoples R China.
摘要：
In the title compound, [Zn(C14H8Br2N 2O3)(C5H5N)2], the ZnII ion is coordinated by one N and two O atoms from a Schiff base ligand and by the N atoms of two pyridine molecules to form a distorted trigonal-bipyramidal geometry. © 2006 International Union of Crystallography All rights reserved.
语种：
英文
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芘冠醚双功能化杯[4]芳烃的合成与表征
作者：
张德华;吕鉴泉
期刊：
化学试剂 ,2006年28(10):627-628,631 ISSN：0258-3283
作者机构：
[吕鉴泉; 张德华] 湖北师范学院;华中师范大学
关键词：
芘;冠醚;杯芳烃;合成
摘要：
以杯[4]芳烃为原料，经碱催化合成了26，28-双(1-乙酰基芘)-5，11，17，23-四叔丁基杯[4]-冠-6，产物结构经IR、~1HNMR和元素分析表征。该衍生物为锥形结构。
语种：
中文
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An effective bifunctional thiourea catalyst for highly enantio- and diastereoselective Michael addition of cyclohexanone to nitroolefins
作者：
Cao, Yi-Ju;Lu, Hai-Hua;Lai, Yuan-Yuan;Lu, Liang-Qiu;Xiao, Wen-Jing*
期刊：
Synthese ,2006年2006(22):3795-3800 ISSN：1111-4924
通讯作者：
Xiao, Wen-Jing
作者机构：
[Lai, Yuan-Yuan; Lu, Liang-Qiu; Lu, Hai-Hua; Xiao, WJ; Cao, Yi-Ju] Cent China Normal Univ, Key Lab Pesticide & Chem Biol, Minist Educ, Coll Chem, Wuhan 430079, Hubei, Peoples R China.;[Xiao, Wen-Jing] Cent China Normal Univ, Key Lab Pesticide & Chem Biol, Minist Educ, Coll Chem, 152 Luoyu Rd, Wuhan 430079, Hubei, Peoples R China.
通讯机构：
[Xiao, Wen-Jing] C;Cent China Normal Univ, Key Lab Pesticide & Chem Biol, Minist Educ, Coll Chem, 152 Luoyu Rd, Wuhan 430079, Hubei, Peoples R China.
关键词：
Asymmetric catalysis;Michael addition;bifunctional thiourea catalyst;organocatalysis;nitroolefins
摘要：
A series of new tunable and bifunctional thiourea catalysts have been synthesized and their catalytic activities are evaluated in the direct Michael addition of cyclohexanone to nitroolefins. High isolated yields (up to 97%), enantioselectivities (up to 98%) and diastereoselectivities (up to 99:1) were obtained under the optimal conditions. ©Georg Thieme Verlag Stuttgart.
语种：
英文
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