Bis(benzimidazol-2-ylmethyl)amine tetrahydrate
作者：
Meng, Xiang-Gao* ;Mei, Fu-Sheng;Liao, Zhan-Ru
期刊：
ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY ,2006年62(9):o4120-o4122 ISSN：2053-2296
通讯作者：
Meng, Xiang-Gao
作者机构：
[Meng, Xiang-Gao; Mei, Fu-Sheng; Liao, Zhan-Ru] Cent China Normal Univ, Dept Chem, Wuhan 430079, Peoples R China.
通讯机构：
[Meng, Xiang-Gao] C;Cent China Normal Univ, Dept Chem, Wuhan 430079, Peoples R China.
摘要：
In the title compound, C16H15N5· 4H2O, the two independent molecules of the asymmetric unit are linked into a three-dimensional structure by a combination of classical hydrogen bonds, C-H⋯π and aromatic π-π interactions. © 2006 International Union of Crystallography. All rights reserved.
语种：
英文
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大学化学双语教学浅析
作者：
章骏斌
期刊：
高等继续教育学报 ,2006年20(2):50-52 ISSN：2095-5987
作者机构：
华中师范大学,化学学院,武汉,430079;[章骏斌] 华中师范大学
关键词：
双语教学;高校教育;化学高等教育
摘要：
高校教育中的双语课程已经日趋流行。各高校都力争把双语课程打造为精品课程,但实际中出现良莠不齐的状况;广大学生对双语课程的认同感也存在很大的差异。本文就双语教学的起源、现状和特点进行了分析,并就未来的改进方向提出一些看法。
语种：
中文
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论中学化学教学中创新能力的培养
作者：
安静
期刊：
高等继续教育学报 ,2006年(S1):45-46+58 ISSN：2095-5987
作者机构：
华中师范大学化学学院,武汉430079
关键词：
中学化学教学;创新能力;培养途径
摘要：
化学作为自然学科的一个分支,在人类生活和生产中发挥着极为重要的作用。中学生是推动科技发展的生力军,他们只有具备较强的创新意识和创新能力,才能推动科技的快速发展。本文就如何在化学教学中培养中学生的创新能力进行了初步探讨。
语种：
中文
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人教版新课标高中化学教材实验新增教学要素分析
作者：
朱瑞雪;王文韬
期刊：
高等继续教育学报 ,2006年20(2):62-64 ISSN：2095-5987
作者机构：
华中师范大学,化学学院,武汉,430079;[王文韬; 朱瑞雪] 华中师范大学
关键词：
化学实验教学;实验教学要素;创新能力培养;教学效率
摘要：
传统高中化学教学注重的是培养具有化学专长的人才,把着眼点放在理论水平与知识技能的提高上,把实验的最终目标也定位于知识的验证和基本操作.而人民教育出版社出版的新课程标准实验教科书给高中实验教学重新定位,加入了新思想、新方法、新特色等新鲜教学要素,旨在使学生在兴奋状态下自主的掌握知识,培养学生的科学素养和综合实验能力,从而提高教学效率.
语种：
中文
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中学化学教育中的绿色化学
作者：
曹琼瑶
期刊：
科技资讯 ,2006年(17):195 ISSN：1672-3791
作者机构：
华中师范大学化学学院,430079
关键词：
绿色化学;中学化学教育;化学实验;化学教师
摘要：
随着时代的发展,化学已成为我们生活中密不可分的一部分.但日益严重的环境问题不断冲击着我们的思想.本文就以绿色化学为主线,从中学绿色化学教育、实验改进、教师绿色意识提高三方面来阐述这个问题.>>详细
语种：
中文
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环氧接枝改性水性丙烯酸树脂的合成研究
作者：
王春艳;陈涛;朱传方;李文
期刊：
应用化工 ,2006年35(1):27-29 ISSN：1671-3206
作者机构：
华中师范大学,化学学院,湖北,武汉,430079;[陈涛; 李文; 王春艳; 朱传方] 华中师范大学
关键词：
环氧树脂;丙烯酸树脂;接枝改性
摘要：
通过丙烯酸酯类单体与环氧树脂接枝共聚反应,对水性丙烯酸树脂进行改性.研究了环氧树脂种类、用量、加料方式、反应温度及中和度等因素对其性能的影响.研究结果表明,当环氧树脂E-44在反应前期加入,用量为6%～9% (占总单体质量分数),反应温度为110℃,中和度为110%时,改性树脂具有较好的成膜性能和优异的物理机械性能.红外光谱分析证实接枝产物的存在;用扫描电镜观察了接枝共聚物的水分散体的粒子形态及大小.
语种：
中文
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浅谈化学中自主学习能力的培养
作者：
李锦;高晚霞
期刊：
现代教育科学 ,2006年(04):118-119 ISSN：1005-5843
作者机构：
广东省东莞中学;华中师范大学化学学院 广东东莞523005;湖北武汉430079
关键词：
自主学习;自主学习能力;探究性学习
摘要：
本文旨在阐述自主学习的内涵、意义及如何在化学教学实践中培养这一能力.
语种：
中文
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稀土微肥的林用概述
作者：
章骏斌
期刊：
闽西职业技术学院学报 ,2006年8(2):125-127 ISSN：1673-4823
作者机构：
华中师范大学,化学学院,湖北,武汉,430079;[章骏斌] 华中师范大学
关键词：
稀土;稀土微肥;稀土林用
摘要：
我国自20世纪80年代中期开展了稀土农用的研究，但在林业上的实际稚广应用还十分有限。多年的研究表明。稀土林用是一项低成本、高效益的林业增产技术。概述了稀土微肥的发展概况及其在林业生产中的应用和效果。并对其增产机理、毒理作用、施用技术和注意事项作了分析介绍；最后结合福建省的实际。对稀土徽肥开发应用的前景进行探讨。
语种：
中文
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Chloro[(4R,9R,14R,19R)-24-chloro-2,21 -dimethyl-3,10,13,20,26- pentaazatetracyclo[203.1.04.9.014,19]hexacosa-1 (26),2(3),20(21),22(23), 24-pentaene]-(methoxo)manganese(II) chloride monohydrate
作者：
Tu, HY;Wang, CJ;Meng, XG;Zhang, AD
* （ 期刊：
ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY ,2006年62(3):m500-m501 ISSN：2053-2296
作者机构：
[Zhang, AD; Meng, XG; Wang, CJ; Tu, HY] Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China.
通讯机构：
[Zhang, AD] C;Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China.
摘要：
In the title compound, [Mn(CH3O)Cl(C23H 34ClN52)]Cl.H2O, the Mn atom is coordinated by five N atoms from the macrocyclic ligand in an approximately planar pentagonal configuration. In addition, the Mn atom is axially coordinated by a methoxy group and a Cl atom, one on each side of the plane. © 2006 International Union of Crystallography All rights reserved.
语种：
英文
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Synthesis and Crystal Structure of 4-Azido-2,2,6,6- Tetramethylpiperidine-l-oxyl Free Radical
作者：
Zhou, BH;Chen, YF;Yin, GD;Wu, AX*
期刊：
Chinese Journal of Structural Chemistry ,2006年25(2):127-130 ISSN：0254-5861
通讯作者：
Wu, AX
作者机构：
[Zhou, BH; Chen, YF; Yin, GD; Wu, AX] College of Chemistry, Central China Normal University
通讯机构：
[Wu, AX ] ;Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China.
关键词：
crystal structure;nitroxide radical;synthesis
摘要：
The title compound 4-azido-2,2,6,6-tetramethylpiperidine-l-oxyl （C9H17N4O, Mr = 197.27） has been synthesized and its structure was determined by single-crystal X-ray diffraction. The crystal belongs to triclinic, space group P1^- with a = 5.8464（12）, b = 8.2476（17）, c = 11.954（2） A°, a = 101.973（4）, β = 97.186（3）, γ, = 100.232（3）°, V = 546.98（19） ,A°^3, Z = 2, Dc= 1.198 g/cm^3, μ（MoKa） = 0.082 mm^-1, F（000） = 214, R = 0.0495 and wR = 0.1355 for 1677 observed reflections with I 〉 2σ（I）. X-ray analysis reveals that the six-membered ring adopts a chair conformation and the bond length of N（1）-O（1） is 1.2838（19）A°.
语种：
英文
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2,6-dibenzhydryl-8b,8c-diphenyl-2,3,5,6,8b,8c-hexahydro-2,3a,4a,6,7a, 8a-hexaaza-1H,4Hcyclopenta[def]fluorene-4,8-dione
作者：
Li, YT;Wang, YZ;Wu, AX*
期刊：
ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY ,2006年62(1):o379-o380 ISSN：2053-2296
通讯作者：
Wu, AX
作者机构：
[Li, YT; Wu, AX; Wang, YZ] Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticides & Chem Biol, Wuhan 430079, Peoples R China.
通讯机构：
[Wu, AX] C;Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticides & Chem Biol, Wuhan 430079, Peoples R China.
摘要：
The title compound, C46H40N6O2, is a glycoluril derivative. The molecule contains four fused rings, viz two nearly planar imidazole rings and two non-planar triazine rings. The triazine rings each have a chair conformation. ©2006 International Union of Crystallography Printed in Great Britain - all rights reserved.
语种：
英文
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Diethyl 2,6-bis(4-methylbenzyl)-4,8-dioxo-2,3,6,7-tetrahydro-1H,5H-2,3a,4a, 6,7a,8a-hexaazacyclopenta[def]fluorene-8b,8c-dicarboxylate
作者：
Guo, Hui-Zhen
* ;She, Neng-Fang
（ ;Li, Yi-Tao
期刊：
ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY ,2006年62(12):o5596-o5597 ISSN：2053-2296
通讯作者：
Guo, Hui-Zhen
作者机构：
[She, Neng-Fang; Li, Yi-Tao; Guo, Hui-Zhen; Guo, HZ] Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticides & Chem Biol, Wuhan 430079, Peoples R China.
通讯机构：
[Guo, Hui-Zhen] C;Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticides & Chem Biol, Wuhan 430079, Peoples R China.
摘要：
The title compound, C30H36N6O6, is a glycoluril derivative with two ethyl acetate substituents on the convex face of the glycouril system. Two equivalent six-membered triazine rings bind the N atoms from separate rings of the glycouril unit to form the flexible sidewalls of a molecular clip. One N atom from each ring caries a 4-methylbenzyl substituent. The crystal structure is stabilized by intermolecular C—H⋯O interactions.
语种：
英文
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Double carbonylation reactions of enynols and thiols to form thioester substituted 6-membered ring lactones
作者：
Cao, Hong;Xiao, Wen-Jing* ;Alper, Howard
期刊：
ADVANCED SYNTHESIS & CATALYSIS ,2006年348(14):1807-1812 ISSN：1615-4150
通讯作者：
Xiao, Wen-Jing
作者机构：
Cent China Normal Univ, Minist Educ, Key Lab Posticide & Chem Biol, Wuhan 430079, Hubei, Peoples R China.;Univ Ottawa, Ctr Catalysis Res & Innovat, Dept Chem, Ottawa, ON K1N 6N5, Canada.;[Xiao, Wen-Jing] Cent China Normal Univ, Minist Educ, Key Lab Posticide & Chem Biol, 152 Luoyu Rd, Wuhan 430079, Hubei, Peoples R China.
通讯机构：
[Xiao, Wen-Jing] C;Cent China Normal Univ, Minist Educ, Key Lab Posticide & Chem Biol, 152 Luoyu Rd, Wuhan 430079, Hubei, Peoples R China.
关键词：
6-membered ring lactones;Double carbonylation;Enynols;Homogeneous catalysis;Palladium;Thiols
摘要：
The double carbonylation reaction of enynols with thiols affords functionalized 6-membered ring lactones. Two kinds of 6-membered ring lactones were obtained by the use of different palladium complexes with added phosphine ligands. © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.
语种：
英文
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2-氨基苯并噻吩并[3,2-d]嘧啶-4(3H)-酮的合成
作者：
徐胜臻;丁明武;肖文精
作者机构：
[徐胜臻; 丁明武; 肖文精] 华中师范大学化学学院教育部农药与化学生物学重点实验室
会议名称：
第七届全国磷化学化工暨第四届海峡化学生物学、生物技术与医药发展讨论会
会议时间：
2006-04
会议地点：
中国河南郑州
摘要：
<正>噻吩并嘧啶酮作为喹啉生物等排体,是一类具有良好的杀菌活性和药理活性的杂环化合物。一些二位取代烷(氧)基噻吩并嘧啶酮显示出较强的杀菌和抗真菌活性,已有很多文献报道了多种该类杂环化合物的合成方法。最近,氮杂Wittig反应广泛地应用于氮杂环的合成,该类反应原料易得、条件温和,已成为一种合成氮杂环的有效手段。我们曾报道应用氮杂Wittig反应合成噻吩并嘧啶酮衍生物(Ⅰ)和(Ⅱ),部分化合物表现出良
语种：
中文
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2-Morpholino-3-p-tolylbenzo[4,5]thieno-[3,2-d]pyrimidin-4(3H)-one
作者：
Xu, Sheng-Zhen;Hu, Yang-Gen;Liu, Ming-Guo;Ding, Ming-Wu*
期刊：
ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY ,2006年62(8):o3428-o3429 ISSN：2053-2296
通讯作者：
Ding, Ming-Wu
作者机构：
[Xu, Sheng-Zhen; Ding, Ming-Wu; Hu, Yang-Gen; Liu, Ming-Guo; Ding, MW] Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticides & Chem Biol, Wuhan 430079, Peoples R China.
通讯机构：
[Ding, Ming-Wu] C;Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticides & Chem Biol, Wuhan 430079, Peoples R China.
摘要：
In the crystal structure of the title compound, C21H 19N3O2S, there are two crystallographically independent molecules, which are linked by C-H⋯O hydrogen bonds and π-π interactions. © 2006 International Union of Crystallography. All rights reserved.
语种：
英文
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3-(4-chlorophenyl)-5-ethyl-6-methyl-2-morpholino-thieno[2,3-d] pyrimidin-4(3H)-one
作者：
Fang, Zheng-Dong* ;Ding, Ming-Wu
期刊：
ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY ,2006年62(7):o2869-o2871 ISSN：2053-2296
通讯作者：
Fang, Zheng-Dong
作者机构：
[Fang, Zheng-Dong] Hubei Normal Univ, Dept Environm Chem & Engn, Huangshi 435002, Peoples R China.;Cent China Normal Univ, Key Lab Pesticides & Chem Biol, Minist Educ, Coll Chem, Wuhan 430079, Peoples R China.
通讯机构：
[Fang, Zheng-Dong] H;Hubei Normal Univ, Dept Environm Chem & Engn, Huangshi 435002, Peoples R China.
摘要：
In the title compound, C19H20ClN3O 2S, the two fused rings of the thieno[2,3-d]pyrimidin-4(3H)-one system are almost coplanar. The packing of the molecules in the crystal structure is mainly governed by intermolecular C-H⋯O hydrogen-bonding and π-π interactions. © 2006 International Union of Crystallography. All rights reserved.
语种：
英文
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Synthesis and Bioactivities 2-Alkylthio-5-chlorophenyl) methylidene-4H-Imidazolin-4-ones
作者：
杨风岭;丁明武;刘钊杰
作者机构：
[杨风岭; 丁明武; 刘钊杰] Department of Chemistry,Xuchang University, Xuchang 461000,P.R.China;[杨风岭; 丁明武; 刘钊杰] College of Chemistry,Central China Normal University,Wuhan 430079,P.R.China;[杨风岭; 丁明武; 刘钊杰] College of Chemistry,entral China Normal University,Wuhan 430079,P.R.China
会议名称：
第七届全国磷化学化工暨第四届海峡化学生物学、生物技术与医药发展讨论会
会议时间：
2006-04
会议地点：
中国河南郑州
摘要：
<正>4H-Imidazolin-4-ones due to their uses as herbicides and fungicides, one of the most flourish in the research and development of agrochemicals, are important heterocycles, especial some 2-methylthioimidazolinone derivatives as fungicides.Since a novel mitochondrial respiratory inhibitor （5-methyl-2-methylthio -5-phenyl-3-phenyl-amino -3,5-dihydro-imidazol-4-one） was found to show high fungicidal activities, many other 2-methylthio-imidazolinone
语种：
中文
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Insecticidal lead identification by screening benzopyrano[4,3-c] pyrazol-3(2H)-ones library constructed from multiple-parallel synthesis under microwave irradiation
作者：
Zhou, Zhong-Zheng;Yang, Guang-Fu*
期刊：
Bioorganic & Medicinal Chemistry ,2006年14(24):8666-8674 ISSN：0968-0896
通讯作者：
Yang, Guang-Fu
作者机构：
[Yang, Guang-Fu; Zhou, Zhong-Zheng; Yang, GF] Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China.
通讯机构：
[Yang, Guang-Fu] C;Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China.
关键词：
Benzopyrano[4,3-c]pyrazol-3(2H)-ones;Combinatorial chemistry;Insecticidal activity;Lead structure;Microwave-assisted parallel synthesis
摘要：
A rapid library-generation via liquid-phase multiple-parallel synthesis of 2-(substituted)benzyl-1-benzopyrano[4,3-c]pyrazol-3(2H)-ones, bearing two points of diversity, under microwave irradiation was successfully performed using chromenone-3-carboxylic acids as starting materials. Compared to an identical library generated by conventional parallel synthesis, microwave-assisted parallel synthesis dramatically decreased reaction times from an average of 16 h to 13 min, and the yields of products and intermediates were improved in most cases. A bioassay indicated that the compounds of the library exhibited excellent insecticidal activity against T. cinnabarinus at the dosage of 250 mg L-1, and some compounds still exhibited insecticidal activity when the dosage was reduced to 50 mg L-1. This shows that 2-(substituted) benzyl-1-benzopyrano[4,3-c]pyrazol-3(2H)-ones might be used as lead structures for further optimization. To our knowledge, this is the first report about the application of solution-phase multiple-parallel synthesis under microwave irradiation to construct libraries of benzopyrano-[4,3-c]pyrazol-3(2H)-ones with insecticidal activity. The coupling of microwave technology with liquid-phase parallel synthesis constitutes a novel and particularly attractive avenue for the rapid generation of structurally diverse libraries for lead discovery. © 2006 Elsevier Ltd. All rights reserved.
语种：
英文
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Understanding the structure–activity and structure–selectivity correlation of cyclic guanine derivatives as phosphodiesterase-5 inhibitors by molecular docking, CoMFA and CoMSIA analyses
作者：
Yang, GF
* （ ;Lu, HT;Xiong, Y;Zhan, CG
期刊：
Bioorganic & Medicinal Chemistry ,2006年14(5):1462-1473 ISSN：0968-0896
作者机构：
[Yang, GF] Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China.;Univ Kentucky, Coll Pharm, Dept Pharmaceut Sci, Lexington, KY 40536 USA.
通讯机构：
[Yang, GF] C;Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China.
关键词：
Binding mode;Enzyme;Inhibitor;Phosphodiesterase;Selective inhibition;Structure-activity correlation
摘要：
Molecular docking and 3D-QSAR analyses were performed to understand how PDE5 and PDE6 interact with a series of (49) cyclic guanine derivatives. Using the conformations of the compounds revealed by molecular docking, CoMFA and CoMSIA analyses resulted in the first quantitative structure-activity relationship (QSAR) and first quantitative structure-selectivity relationship (QSSR) models (with high cross-validated correlation coefficient q(2) and conventional correlation coefficient r(2) values) for predicting the inhibitory activity against PDE5 and the selectivity against PDE6. The high q(2) and r(2) values, along with further testing, indicate that the obtained 3D-QSAR and 3D-QSSR models will be valuable in predicting both the inhibitory activity and selectivity of cyclic guanine derivatives for these protein targets. A set of 3D contour plots drawn based on the 3D-QSAR and 3D-QSSR models reveal some useful clues to improve both the activity and selectivity by modifying structures of the compounds. It has been demonstrated that both the steric and electrostatic factors should appropriately be taken into account in future rational design and development of more active and more selective PDE5 inhibitors for the therapeutic treatment of erectile dysfunction (ED). (c) 2005 Elsevier Ltd. All rights reserved.
语种：
英文
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An efficient intramolecular Stetter reaction in room temperature ionic liquids promoted by microwave irradiation
作者：
Zhou, Zhong-Zhen;Ji, Feng-Qing;Cao, Min;Yang, Guang-Fu*
期刊：
ADVANCED SYNTHESIS & CATALYSIS ,2006年348(14):1826-1830 ISSN：1615-4150
通讯作者：
Yang, Guang-Fu
作者机构：
[Yang, Guang-Fu; Cao, Min; Zhou, Zhong-Zhen; Ji, Feng-Qing; Yang, GF] Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China.
通讯机构：
[Yang, Guang-Fu] C;Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China.
关键词：
Chroman-4-ones;Ionic liquids;Microwave heating;Stetter reaction
摘要：
This communication describes the first report of a microwave-assisted intramolecular Stetter reaction using imidazolium-type room temperature ionic liquids (RTILs) as solvents, with thiazolium salts and Et3N as catalysts. The features such as good to excellent yields, shorter reaction time (5-20 min), and recyclable and reusable ionic liquid and catalyst make this method an environmentally benign and highly efficient procedure for the preparation of chromanone derivatives. © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.
语种：
英文
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