作者机构:
[韩贤权; 朱庆; 丁雨淋] State Key Laboratory of Information Engineering in Surveying Mapping and Remote Sensing, Wuhan University, Wuhan , China;[周东波] National Engineering Research Center for E-Learning Science Hall, Huazhong Normal University, Wuhan , China;[丁雨淋] Institute of Space and Earth Information Science, The Chinese University of Hong Kong, Hong Kong , Hong Kong;[朱庆] Faculty of Geosciences and Environmental Engineering, Southwest Jiaotong University, Chengdu , China;[韩贤权] Engineering Safety and Disaster Prevention Department, Yangtze River Scientific Research Institute, Wuhan , China
通讯机构:
State Key Laboratory of Information Engineering in Surveying Mapping and Remote Sensing, Wuhan University, Wuhan, China
期刊:
IEEE Transactions on NanoBioscience,2014年13(2):80-88 ISSN:1536-1241
通讯作者:
Zhao, Junmin
作者机构:
[Zhao, Junmin] Henan Univ Urban Construct, Pingdingshan 467036, Peoples R China.;[He, Tingting; Shen, Xianjun; Hu, Xiaohua; Li, Peng; Zhang, Ming] Cent China Normal Univ, Sch Comp, Wuhan 430079, Peoples R China.;[Zhao, Junmin] Natl Engn Res Ctr E Learning, Wuhan 430079, Peoples R China.
通讯机构:
[Zhao, Junmin] N;Natl Engn Res Ctr E Learning, Wuhan 430079, Peoples R China.
关键词:
Biological network;gene co-express;protein complex;weighted PPI network
摘要:
Recent studies have shown that protein complex is composed of core proteins and attachment proteins, and proteins inside the core are highly co-expressed. Based on this new concept, we reconstruct weighted PPI network by using gene expression data, and develop a novel protein complex identification algorithm from the angle of edge (PCIA-GeCo). First, we select the edge with high co-expressed coefficient as seed to form the preliminary cores. Then, the preliminary cores are filtered according to the weighted density of complex core to obtain the unique core. Finally, the protein complexes are generated by identifying attachment proteins for each core. A comprehensive comparison in term of F-measure, Coverage rate, P-value between our method and three other existing algorithms HUNTER, COACH and CORE has been made by comparing the predicted complexes against benchmark complexes. The evaluation results show our method PCIA-GeCo is effective; it can identify protein complexes more accurately.
作者机构:
[Liu, Sanya; Tie, Lu; Liu, Zhi; Shi, Yinghui; Min, Lei] National Engineering Research Center for E-Learning, Central China Normal University, No. 152, Luoyu Road, Wuhan 430079, China
作者:
Yang, Hongyun;Chen, Xuhui*;Yang, Zongkai;Zhu, Xiaoliang;Chen, Yi
期刊:
International Journal of Future Generation Communication and Networking,2014年7(6):165-180 ISSN:2233-7857
通讯作者:
Chen, Xuhui
作者机构:
[Yang, Hongyun] College of Education, Hubei University, Hubei, China;[Chen, Yi] Computer School, Central China Normal University, Hubei, China;[Yang, Zongkai; Zhu, Xiaoliang] National Engineering Research Center for E-learning, Central China Normal University, Hubei, China;[Chen, Xuhui] College of Mathematics and Computer Science, Wuhan Textile University, Hubei, China
作者机构:
[Wu, Di; Peng, Xian] Cent China Normal Univ, Natl Engn Res Ctr E Learning, Wuhan, Peoples R China.
会议名称:
International Conference on Intelligent Environments (IE)
会议时间:
JUN 30-JUL 04, 2014
会议地点:
Shanghai, PEOPLES R CHINA
会议主办单位:
[Wu, Di;Peng, Xian] Cent China Normal Univ, Natl Engn Res Ctr E Learning, Wuhan, Peoples R China.
关键词:
cloud computing;E-Learning standard;cloud-based education standard
摘要:
Cloud computing technology provides a convenient way for the distribution and application of educational resource, which becomes the hotspot of ICT in education. Based on in-depth study of standards in cloud computing and E-Learning, the paper analyzes the requirement, key techniques and actual application of cloud computing education, constructs a standard architecture, elaborates the relationship between different standards in this architecture.
期刊:
2011 INTERNATIONAL CONFERENCE ON FUZZY SYSTEMS AND NEURAL COMPUTING (FSNC 2011), VOL I,2014年643:142-147 ISSN:1662-7482
通讯作者:
Wang, Min
作者机构:
[Gu Caidong; Wang Min; Dai Minli] Suzhou Vocat Univ, Dept Comp Engn, Suzhou, Peoples R China.;[Sun Chuanming] Huazhong Normal Univ, Natl Engn Res Ctr e Learning, Wuhan, Peoples R China.
会议名称:
2014 2nd Asian Pacific Conference on Mechatronics and Control Engineering(APCMCE 2014)
会议时间:
2014-01-01
会议地点:
Hong Kong,China
会议主办单位:
[Wang, Min;Dai, Minli] Suzhou Vocat Univ, Dept Comp Engn, Suzhou, Peoples R China.^[Sun, Chuanming] Cent China Normal Univ, Natl Res Ctr Cultural Ind, Wuhan, Peoples R China.
摘要:
It is important to research the application of virtual world used in special education to promote the informatization of special education. Firstly, this paper analyzes the current problems faced by special education. Secondly, an application structure of virtual world for special education is designed based on Second Life. Finally, its advantages and the likely problems for Educators are discussed. This research can provide some reference for educators who should bring virtual world into special education classroom in future.