摘要：
在中国的制造业已建成了门类齐全、独立完整的产业体系的今天,制造业的重要性已经被越来越多的人所认识.作为制造业后备军培养基地的理工类高职院校,其自身有着与普通高校不同的特点.在理工类院校高职英语课程中实施模块式教学模式,不仅着重语言学习的实用性,也能引起学生跨学科、将文理相结合的学习兴趣,能很好地完成英语教学.目前对模块式教学的相关研究已很多,但如何在理工类高职院校开展主题英语课程的模块式教学研究并不多.本文从分析目前高职院校教学现状开始,分析了工学背景下理工类高职院校英语教学中实施模块化教学的意义,并以"Made in China"产业发展主题为例,详细阐述了课程实施的过程、内容、教学实例、教学策略与实施效果.
摘要：
The rice -crayfish field (i.e., RCF), a recently emerged rice cultivation pattern, has experienced remarkable growth in China over the last decade due to its significant socioeconomic advantages. However, the impacts of expanding RCF areas on the regional -scale ecological environment, particularly concerning methane (CH4) emissions, remain unclear. A major obstacle in addressing this knowledge gap is the absence of accurate and upto-date spatial distribution information on RCF across years. Here, we selected Jianghan Plain which has the largest RCF area in China as the study area. First, we developed a phenology-based identification algorithm using Landsat-7/8 satellite data, which considered the distinctive flooding signatures of RCF during the rice fallow periods, to identify RCF at the regional scale. Second, we employed the DeNitrification-DeComposition (DNDC) model to simulate the CH4 fluxes of various rice cropping systems, including RCF, rice monoculture (RM), ricerapeseed rotation (RR), and rice -wheat rotation (RW). Finally, the effects of RCF expansion during 2014-2019 on regional CH4 emissions were analyzed by comparing six scenarios that simulated the conversion of different rice cropping systems to RCF. Results showed the phenology-based algorithm performed well in extracting RCFs, achieving an overall accuracy >92 % for all years based on 1025 RCF and 2096 non-RCF validation samples. RCF generated the least CH4 flux, followed by RM, RR, and RW. Moreover, shifting from traditional rice cropping systems to RCF reduced CH4 emissions across all cases, with mitigation rates ranging from 4.82 % to 21.85 %, indicating RCF's substantial CH4 mitigation potential. These findings significantly improve our understanding of the ecological effects of RCF cultivation, which is critical for advancing land use planning and decision -making for sustainable agricultural development in China. Our presented evaluation method of integrating the remote sensing mapping algorithm and DNDC model can be easily generalized for other crop types in other regions.
作者机构：
[Guan, Rui; Sun, Yao; Li, Junrong; Liu, Guorong] Cent China Normal Univ, Coll Chem, Int Joint Res Ctr Intelligent Biosensor Technol &, Natl Key Lab Green Pesticide, Wuhan 430079, Peoples R China.;[Yan, Mingzhe] Huazhong Univ Sci & Technol, Wuhan Jinyintan Hosp, Tongji Med Coll, Wuhan 430023, Peoples R China.;[Cheng, Jing] Wuhan Univ Sci & Technol, Sch Publ Hlth, Wuhan 430072, Peoples R China.;[Zhan, Jianbo] Hubei Prov Ctr Dis Control & Prevent, Inst Hlth Inspect & Testing, Wuhan 430072, Peoples R China.;[Wuethrich, Alain; Trau, Matt; Wuethrich, A] Univ Queensland, Australian Inst Bioengn & Nanotechnol, Ctr Personalized Nanomed, Brisbane, Qld 4072, Australia.
通讯机构：
[Wuethrich, A ] U;[Sun, Y ] C;Cent China Normal Univ, Coll Chem, Int Joint Res Ctr Intelligent Biosensor Technol &, Natl Key Lab Green Pesticide, Wuhan 430079, Peoples R China.;Univ Queensland, Australian Inst Bioengn & Nanotechnol, Ctr Personalized Nanomed, Brisbane, Qld 4072, Australia.
摘要：
The molecular detection of multiple respiratory viruses provides evidence for the rational use of drugs and effective health management. Herein, we developed and tested the clinical performance of an electrohydrodynamic-driven nanobox-on-mirror platform (E-NoM) for the parallel, accurate, and sensitive detection of four respiratory viral antigens. The E-NoM platform uses gold-silver alloy nanoboxes as the core material with the deposition of a silver layer as a shell on the core surfaces to amplify and enable a reproducible Raman signal readout that facilitates accurate detection. Additionally, the E-NoM platform employs gold microelectrode arrays as the mirror with electrohydrodynamics to manipulate the fluid flow and enhance molecular interactions for an improved biosensing response. The presence of viral antigens binds the nanobox-based core-shell nanostructure on the gold microelectrode and creates the nanocavity with extremely strong "hot spots" to benefit sensitive analysis. Significantly, in a large clinical cohort with 227 patients, the designed E-NoM platform demonstrates the capability of screening respiratory infection with achieved clinical specificity, sensitivity, and accuracy of 100.0, 96.48, and 96.91%, respectively. It is anticipated that the E-NoM platform can find a position in clinical usage for respiratory disease diagnosis.
期刊：
Science of The Total Environment,2024年922:171299 ISSN：0048-9697
通讯作者：
Mingqing Chen
作者机构：
[Xu, Ke; Jiang, Mengling; Wang, Shuxin; Han, Qi; Gao, Xiao; Du, Wanting; Wang, Yunyi] Hubei Key Laboratory of Genetic Regulation and Integrative Biology, School of Life Sciences, Central China Normal University, Wuhan 430079, Hubei, China;[Chen, Mingqing] Hubei Key Laboratory of Genetic Regulation and Integrative Biology, School of Life Sciences, Central China Normal University, Wuhan 430079, Hubei, China. Electronic address: chenmq@mail.ccnu.edu.cn
通讯机构：
[Mingqing Chen] H;Hubei Key Laboratory of Genetic Regulation and Integrative Biology, School of Life Sciences, Central China Normal University, Wuhan 430079, Hubei, China
摘要：
After aging in the environment, some nanoplastics will carry different charges and functional groups, thereby altering their toxicological effects. To evaluate the potential impact of aging of nanoplastics on the mammalian reproductive system, we exposed C57BL/6 male mice to a dose of 5mg/kg/d polystyrene nanoparticles (PS-NPs) with different functional groups (unmodified, carboxyl functionalized and amino functionalized) for 45days for this study. The results suggest that PS-NPs with different functional groups triggered oxidative stress, a decreased in the testis index, disruption of the outer wall of the seminiferous tubules, reduction in the number of spermatogonia cells and sperm counts, and an increased in sperm malformations. We performed GO and KEGG enrichment analysis on the differentially expressed proteins, and found they were mainly enriched in protein transport, RNA splicing and mTOR signaling. We confirmed that the PI3K-AKT-mTOR pathway is over activated, which may lead to reduction of spermatogonia stem cells by over differentiation. Strikingly, PS-NPs with functional group modifications are more toxic than those of unmodified polystyrene, and that PS-NPs with positively charged amino modifications are the most toxic. This study provides a new understanding for correctly evaluating the toxicological effects of plastic aging, and of the mechanism responsible for the reproductive toxicity caused by nanoplastics.
期刊：
Journal of Mathematical Analysis and Applications,2024年530(1):127636 ISSN：0022-247X
通讯作者：
Duan, R
作者机构：
[Duan, Ran; Chang, Shengchuang] Cent China Normal Univ, Sch Math & Stat, Hubei Key Lab Math Sci, Wuhan 430079, Peoples R China.
通讯机构：
[Duan, R ] C;Cent China Normal Univ, Sch Math & Stat, Hubei Key Lab Math Sci, Wuhan 430079, Peoples R China.
关键词：
Navier-Stokes-quantum equations;Rayleigh-Taylor instability;Hadamard sense
摘要：
Consider the linear and nonlinear Rayleigh-Taylor instability of the three-dimensional incompressible viscous Navier-Stokes-Quantum equations. For linearized problem, we determine the critical number.cprecisely. Then, we construct a linear growth solution by a modified variational method for k <.k(c). In addition, we show that.cis infinite for a special steady state <(rho)over bar>, which implies that quantum potential inhibit the instability instead of cutting it off. Based on this unstable linear solution and the priori estimates of the smooth solution to the perturbed problem, we establish the nonlinear instability of the density and the velocities in the sense of Hadamard. Compared with the related study on Navier-Stokes-Korteweg equations (Zhang (2022) [41]), we do not ask the capillarity coefficient to be small. (c) 2023 Elsevier Inc. All rights reserved.
关键词：
Compressible Navier-Stokes-Allen-Cahn system;Strong/classical solutions;Density-dependent viscosity;Large initial data
摘要：
This paper is concerned with a one-dimensional isentropic compressible Navier-Stokes-Allen-Cahn system with density-dependent viscosity, which models the motion of a mixture of two viscous compressible fluids. The case when the pressure $ p(\rho) = \rho^\gamma $, the viscosity $ \nu(\rho, \chi) = \rho^\alpha $, the interface thickness $ \delta(\rho) = \rho^\beta $ and the relaxation time function $ a(\rho, \chi, \chi_y) = \rho^\lambda $ is considered, where $ \rho $ and $ \chi $ are the density and the phase variable, respectively, and $ \gamma, \alpha, \beta, \lambda\in\mathbb{R} $ are parameters. Under some suitable assumptions on the parameters $ \gamma , \alpha, \beta, \lambda $ and the initial data, we prove the global existence and large-time behavior of nonvacuum strong and classical solutions to its Cauchy problem with large initial data. This appears to be the first global existence result on the Cauchy problem of the compressible Navier-Stokes-Allen-Cahn system with density-dependent viscosity and large data.
摘要：
This paper focuses on the existence of positive solutions for the following weakly coupled Schrödinger system with supercritical growth except at the origin: $ \begin{equation*} \left\{ \begin{array}{ll} -\Delta u_1 = \mu_1|u_{1}|^{p(r) - 2}u_1 + \beta|u_{2}|^{\frac{p(r)}{2}}|u_1|^{\frac{p(r)}{2}-2}u_{1}, & x\in B_1(0), \\ -\Delta u_2 = \mu_2|u_{2}|^{p(r) - 2}u_{2} + \beta|u_{1}|^{\frac{p(r)}{2}}|u_2|^{\frac{p(r)}{2}-2}u_{2}, & x\in B_1(0), \end{array} \right. \end{equation*} $ where $ B_1(0) $ is an unit ball $ {\mathbb{R}^N} $ with $ N\ge 3 $, $ \beta\in\mathbb{R} $ is a coupling constant, $ \mu_1,\mu_2\in {\mathbb R} $ are constants, $ p(r) = 2^* + r^{\alpha} $ with $ 2^* = \frac{2N}{N-2} $. Assuming that $ 0<{\alpha}<\min\{\frac{N}{2},N-2\} $, we apply concentration-compactness idea to show that the problem has a positive solution provided that $ \beta>0 $ if $ N\ge 5 $ and $ \beta\in(0,\beta_0]\cup[\beta_1,+\infty) $ for some positive constants $ \beta_0<\beta_1 $ if $ N = 3,4 $.
作者机构：
[Jian Feng Wang] School of Mathematics and Statistics, Shandong University of Technology, Zibo, P. R. China;[Xing Yu Lei; Shu Chao Li] Faculty of Mathematics and Statistics, Central China Normal University, Wuhan, P. R. China;[Zoran Stanić] Faculty of Mathematics, University of Belgrade, Belgrade, Serbia
通讯机构：
[Zoran Stanić] F;Faculty of Mathematics, University of Belgrade, Belgrade, Serbia
摘要：
The eccentricity matrix of a graph is obtained from the distance matrix by keeping the entries that are largest in their row or column, and replacing the remaining entries by zero. This matrix can be interpreted as an opposite to the adjacency matrix, which is on the contrary obtained from the distance matrix by keeping only the entries equal to 1. In the paper, we determine graphs having the second largest eigenvalue of eccentricity matrix less than 1.
作者机构：
[Huang, Jing] Guangzhou Univ, Sch Math & Informat Sci, Guangzhou, Peoples R China.;[Geng, Xianya] Anhui Univ Sci & Technol, Sch Math & Big Data, Huainan, Peoples R China.;[Zhou, Zihan] Cent China Normal Univ, Fac Math & Stat, Wuhan, Peoples R China.;[Zhou, Zihan] Cent China Normal Univ, Key Lab Nonlinear Anal & Applicat, Minist Educ, Wuhan, Peoples R China.
通讯机构：
[Zhou, ZH ] C;Cent China Normal Univ, Fac Math & Stat, Wuhan, Peoples R China.;Cent China Normal Univ, Key Lab Nonlinear Anal & Applicat, Minist Educ, Wuhan, Peoples R China.
摘要：
Identifying the graph with maximum or minimum spectral radius among a given class of graphs is a central problem in extremal spectral graph theory, known as the Brualdi- Solheid problem. For a graph G = (V-G, E-G), a subset S subset of V-G is called a maximum dissociation set if the induced subgraph G[S] does not contain P-3 as its subgraph, and the subset has maximum cardinality. The dissociation number of G is the number of vertices in a maximum dissociation set of G. In this paper, we first characterize all the connected graphs (resp. bipartite graphs, trees) having maximum spectral radius among connected graphs (resp. bipartite graphs, trees) with given order and dissociation number. Secondly, we show that the connected n-vertex graph with dissociation number phi having minimum spectral radius is a tree, where phi >= [2/3n] . Finally, we determine the graphs having minimum spectral radius with fixed order n and dissociation number phi is an element of {2, [2n/3], n - 1, n - 2}.(c) 2023 Elsevier B.V. All rights reserved.
作者机构：
[Zhou, Zihan; Li, Shuchao] Cent China Normal Univ, Fac Math & Stat, Wuhan 430079, Peoples R China.;[Zhou, Zihan; Li, Shuchao] Cent China Normal Univ, Key Lab Nonlinear Anal & Applicat, Minist Educ, Wuhan 430079, Peoples R China.;[Sun, Wanting] Shandong Univ, Data Sci Inst, Jinan 250100, Peoples R China.;[Wei, Wei] Shanghai Univ Engn Sci, Ctr Intelligent Comp & Appl Stat, Sch Math Phys & Stat, Shanghai 201620, Peoples R China.;[Zhang, Minjie; Zhang, MJ] Hubei Univ Arts & Sci, Sch Math & Stat, Xiangyang 441053, Peoples R China.
通讯机构：
[Zhang, MJ ] H;Hubei Univ Arts & Sci, Sch Math & Stat, Xiangyang 441053, Peoples R China.
关键词：
Signed mixed graph;Eisenstein matrix;Spectral radius
摘要：
A mixed graph M-G is obtained from a simple graph G by orienting an edge subset of G. A signed mixed graph is a mixed graph with arcs and edges signed + or -. The unit Eisenstein matrix (epsilon-matrix for short) of a signed mixed graph was recently introduced by Wissing and van Dam [32]. This novel matrix is indexed by the vertices of the signed mixed graph, and the entry corresponding to a positive arc from u to v is equal to omega = 1+i root 3/2 (and its symmetric entry is (omega) over bar = 1-i root 3/2); the entry corresponding to a negative arc is equal to -omega (and its symmetric entry is -(omega) over bar); the entry corresponding to a positive edge is equal to 1; the entry corresponding to a negative edge is equal to -1; and 0 otherwise. In this paper, we study the spectral properties of this epsilon-matrix. We characterize all the signed mixed graphs whose eigenvalues are contained in (-alpha, alpha) for alpha is an element of {root 2, root 3, root 2} .(c) 2023 Elsevier B.V. All rights reserved.
作者机构：
[Zhao, Qinqin] MianYang Teachers Coll, Deans Off, Mianyang, Peoples R China.;[Wang, Zheng; Bian, Yueran; Zeb, Irum; Zhang, Yan] Huazhong Univ Sci & Technol, Sch Educ, Wuhan, Peoples R China.;[Yang, Caihong] Cent China Normal Univ, Sch Psychol, Wuhan, Peoples R China.;[Chen, Han] MianYang Teachers Coll, President Off, Mianyang, Peoples R China.;[Wang, Pu; Wang, P] Sun Yat Sen Univ, Affiliated Hosp 7, Dept Rehabil Med, Shenzhen, Peoples R China.
通讯机构：
[Wang, P ] S;[Zhang, Y ] H;[Yang, CH ] C;Cent China Normal Univ, Sch Psychol, Wuhan, Peoples R China.;Sun Yat Sen Univ, Affiliated Hosp 7, Dept Rehabil Med, Shenzhen, Peoples R China.
关键词：
anxiety;anxiety without depression;cognitive control network;depression;fNIRS
摘要：
Anxiety is a common psychological disorder associated with other mental disorders, with depression being the most common comorbidity. Few studies have examined the neural mechanisms underlying anxiety after controlling for depression. This study aimed to explore whether there are differences in cortical activation in anxiety patients with different severities whose depression are normal. In the current study, depression levels were normal for 366 subjects-139 healthy subjects, 117 with mild anxiety, and 110 with major anxiety. Using the Hospital Anxiety and Depression Scale (HADS) and a verbal fluency task (VFT) to test subjects' anxiety and depression and cognitive function, respectively. A 53-channel guided near-infrared spectroscopic imaging technology (fNIRS) detected the concentration of oxyhemoglobin (oxy-Hb). Correlation analysis between anxiety severity and oxy-Hb concentration in the brain cortex was performed, as well as ANOVA analysis of oxy-Hb concentration among the three anxiety severity groups. The results showed that anxiety severity was significantly and negatively correlated with oxy-Hb concentrations in the left frontal eye field (lFEF) and in the right dorsolateral prefrontal area (rDLPFC). The oxy-Hb concentration in the lFEF and the rDLPFC were significantly lower in the major anxiety disorder group than that in the control group. This suggests that decreased cortical activity of the lFEF and rDLPFC may be neural markers of anxiety symptoms after controlling for depression. Anxiety symptoms without depression may be result from the dysfunction of the cognitive control network (CCN) which includes the lFEF and rDLPFC. Anxiety disorders often experience an internal sense of loss of control and often be associated with depression. This study aimed to explore the neural mechanisms underlying anxiety after controlling for depress ive symptoms. We found that decreased cortical activity of the lFEF and rDLPFC may be neural markers of anxiety symptoms after control depressive symptoms. Anxiety symptoms without depressive symptoms may be result from the dysfunction of cognitive control network including lFEF and rDLPFC.
作者机构：
[Zhang, Jisha] School of Geography and Environmental Science, Guizhou Normal University, Guiyang. 1300565804@qq.com;[Zhang, Chunyan; Luo, Jing] Hubei Provincial Key Laboratory for Geographical Process Analysis and Simulation & College of Urban and Environmental Sciences, Central China Normal University, Wuhan;[Luo, Jing] Hubei High-quality Development Research Institute, Research Office of Hubei Provincial People's Government and Central China Normal University, Wuhan. luojing@mail.ccnu.edu.cn;[Chen, Guolei] School of Geography and Environmental Science, Guizhou Normal University, Guiyang. 201907008@gznu.edu.cn;[Zhang, Chunyan] Hubei High-quality Development Research Institute, Research Office of Hubei Provincial People's Government and Central China Normal University, Wuhan. rhea@mail.ccnu.edu.cn
摘要：
The public health level in a country is closely related to national development and quality of life. In order to appraise the level of health services in the western region of China, panel data of 124 prefecture-level units covering the period 2011 to 2021 was used together with a health evaluation index system based on four dimensions: quality of life, environmental situation, the level of health services and longevity. To assess this, we used entropy weights, standard deviation and coefficient of variation together with the geographical detector model that measures the stratified spatial heterogeneity. The results show that although public health services have improved overall, the various dimensions are still not balanced as longevity did not match up everywhere. While the developmental level of the various health dimensions presents a pattern of a relatively smooth increasing gradient in the west-central- east direction, the situation with respect to the north-centralsouth is more uneven with both ups and downs. However, a trend of continuous enhancement of all health dimensions was found with a significant positive correlation of spatial clustering, with hotspots and 'sub-hotspots' contracting from north to south, while coldspots and 'sub-coldspots' expanded from west to east. This can be seen as the result of multiple factors, with the level of urbanization and economic level as the dominant factors and government guidance, agglomeration capacity and industrial structure being auxiliary.
摘要：
Infiltration is the process of water entering into, and routings through, the subsurface. It has a profound impact on hillslope and catchment runoff. However, because of the hidden and complex subsurface structures, our understanding of rainfall-related infiltration and how it partitions along a topographic gradient remains challenging. In this study, we used two years of field observations of volumetric soil moisture at 25 combinations of topographic positions and soil depths along a steep subtropical forested hillslope. The lateral partition patterns of infiltration and its control factors were investigated based on a new index, percentage of soil water storage increment at each site to all hillslope sites during a rainfall event (PWSI). Our results showed that the active soil layer involved in hillslope lateral flow was distributed within the depths of 10–40 cm. In deep soil depths (i.e., 40–80 cm), lateral flow was more evident under wet initial moisture conditions than under dry initial moisture conditions, whereas rainfall characteristics had a relatively weak effect on it. Unexpectedly, we found the variability of infiltration partitioning remained high in the deeper soil layers. Among the soil properties, sand, bulk density, n, KS, and SOM were conducive to infiltration, whereas clay had the opposite effect. The dominant factors controlling the lateral partition patterns of infiltration across soil depths were sand in the depths of 0–10 cm, topographic gradient in depths of 10–40 cm, and n (parameter of soil retention curve) in the depths of 40–80 cm. Findings of this study reveal the infiltration partitioning indices were useful to quantitatively describe the distribution patterns of infiltration after rainfall events at the hillslope, and provide new insights into the detection of hillslope lateral flow, which is valuable for understanding subsurface hydrological processes and improving water resource management in humid mountain ecosystems.
期刊：
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY,2024年146(9):6307-6316 ISSN：0002-7863
通讯作者：
Chen, FE;Zhou, H
作者机构：
[Zhao, Fei; Dong, Jianghu; Wang, Wei; Chen, Fen-Er; Yan, Qiongjiao; Xuan, Liangming; Chen, Qinlin; Fan, Rundong; Wang, Haifeng] Wuhan Inst Technol, Pharmaceut Res Inst, Sch Chem Engn & Pharm, Wuhan 430205, Peoples R China.;[Zhou, Hui] Cent China Normal Univ, Coll Chem, Wuhan 430079, Hubei, Peoples R China.;[Chen, Fen-Er] Fudan Univ, Engn Ctr Catalysis & Synth Chiral Mol, Dept Chem, Shanghai 200433, Peoples R China.;[Chen, Fen-Er] Shanghai Engn Ctr Ind Catalysis Chiral Drugs, Shanghai 200433, Peoples R China.
通讯机构：
[Zhou, H ] C;[Chen, FE ] W;Wuhan Inst Technol, Pharmaceut Res Inst, Sch Chem Engn & Pharm, Wuhan 430205, Peoples R China.;Cent China Normal Univ, Coll Chem, Wuhan 430079, Hubei, Peoples R China.;Fudan Univ, Engn Ctr Catalysis & Synth Chiral Mol, Dept Chem, Shanghai 200433, Peoples R China.
摘要：
Saturated hydrocarbon bonds are ubiquitous in organic molecules; to date, the selective functionalization of C(sp(3))-H bonds continues to pose a notorious difficulty, thereby garnering significant attention from the synthetic chemistry community. During the past several decades, a wide array of powerful new methodologies has been developed to enantioselectively modify C(sp(3))-H bonds that is successfully applied in asymmetric formation of diverse bonds, including C-C, C-N, and C-O bonds; nevertheless, the asymmetric C(sp(3))-H alkylation is elusive and, therefore, far less explored. In this work, we report a direct and robust strategy to construct highly valuable enantioenriched unnatural α-amino acid (α-AA) cognates and peptides by a copper-catalyzed enantioselective remote C(sp(3))-H alkylation of N-fluorocarboxamides and readily accessible glycine esters under ambient conditions. The key to success lies in the optically active Cu catalyst generated through the coordination of glycine derivatives to enantiopure bisphosphine/Cu(I) species, which is beneficial to the single electronic reduction of N-fluorocarboxamides and the subsequent stereodetermining alkylation. More importantly, all types (primary, secondary, tertiary, and even α-oxy) of δ-C(sp(3))-H bonds could be site- and stereospecifically activated by the kinetically favored 1,5-hydrogen atom transfer (1,5-HAT) step.
