期刊：
INDOOR AIR 2005: PROCEEDINGS OF THE 10TH INTERNATIONAL CONFERENCE ON INDOOR AIR QUALITY AND CLIMATE, VOLS 1-5,2005年15:3691-3695 ISSN：0908-5920
通讯作者：
Yang, X
作者机构：
[He, HJ; Lu, ZS; Wu, J; Yan, Y; Li, CM; Liu, HL; Yang, X] Cent China Normal Univ, Coll Life Sci, Wuhan 430079, Peoples R China.
通讯机构：
[Yang, X] C;Cent China Normal Univ, Coll Life Sci, Wuhan 430079, Peoples R China.
会议名称：
10th International Conference on Indoor Air Quality and Climate (Indoor Air 2005)
会议时间：
SEP 04-09, 2005
会议地点：
Beijing, PEOPLES R CHINA
会议主办单位：
Cent China Normal Univ, Coll Life Sci, Wuhan 430079, Peoples R China.
关键词：
IAQ;formaldehyde;blinking frequency;irritant intensity;substance P
摘要：
To find out reliable biomarkers in China for acute irritation caused by indoor air pollutants, we carried out this study. A controlled human exposure experiment was used as the main research method. Subject eyes were exposed to gaseous formaldehyde at different doses (0 mg/m(3), 1.0 mg/m(3) 2.0 mg/m(3), 3.0 mg/m(3)) five minutes a day for 4 days. The content of substance P in nasal lavage was determined by radio immune assay (RIA), and the blinking frequency and irritant intensity of their eyes were measured at the same time. The results showed that there were dose-dependent effects between blinking frequency and formaldehyde levels (r=0.980, P < 0.05), and so were there between irritant intensity and formaldehyde levels (r=0.985, P < 0.05). The content of substance P in nasal lavage increased after exposures, especially after the exposure of 3mg/m(2) formaldehyde (p < 0.05). This might explain that formaldehyde could stimulate trigeminal nerve ends of the eyes, which would release substance P from its nasal branches through axon reflex.
摘要：
To explore if the NOS level in airway is associated with air formaldehyde. In this study 24 male Kun Ming mice were divided into 4 exposure groups (0 mg/m(3), 0.5 mg/m(3), 1.0 mg/m(3), 3.0 mg/m(3)) for 72h continuously. After exposure the NOS activities and the NO detection rate in lungs of mice were measured with reagent kits. The results showed that along with the formaldehyde ascension the NOS activities were restrained at first and then improved significantly (P<0.05), while the NO detection rate showed the similar regulation. We suggest that formaldehyde play dual effects in vivo: at a low formaldehyde exposure (<= 0.5 mg/m(3)), the NOS activities in lungs is restrained. However, the repeated high formaldehyde exposure would alter the VR1 mRNA expression levels in the lung of mice, then the NOS activities shall be increased and the NO concentration in airway will also be ascended.
期刊：
Journal of Phycology,2005年41(2):366-369 ISSN：0022-3646
通讯作者：
Guo, HL
作者机构：
[Guo, HL] Wuhan Univ, Coll Life Sci, Wuhan 430072, Peoples R China.;Wuhan Univ, Coll Chem & Mol Sci, Wuhan 430072, Peoples R China.;Cent China Normal Univ, Coll Life Sci, Wuhan 430079, Peoples R China.
通讯机构：
[Guo, HL] W;Wuhan Univ, Coll Life Sci, Wuhan 430072, Peoples R China.
作者机构：
College of Life Science, Central China Normal University, Wuhan 430079, China;Nanyang Technological;Nanyang Technological University, Nanyang Avenue, 639798, Singapore
会议名称：
第十届室内空气品质和质量国际学术会议(Proceedings of the 10th International Conference on Indoor Air Quality and Climate)
摘要：
Formaldehyde, which is well known as a toxic gas and an exogenous compound, is also produced endogenously via cytochrome P450 (CYP) mediated demethylation of compounds containing the CH3N or CH3O functionality.As the similarity to the accepted novel signaling molecules endogenous nitric oxide (NO), carbon monoxide (CO),and hydrogen sulfide (H2S), we hypothesized that endogenous formaldehyde may be another novel signaling molecule. We first compared the three signaling molecules to give the minimal sense criteria for signaling molecule. Formaldehyde fits with all the criteria. We also proposed the possible roles of endogenous formaldehyde in order to give a basis for further study. Formaldehyde may regulate NO level, can influence the structure of macromolecules such as DNA and proteins at molecular level. This hypothesis may start a new direction in the further study on endogenous formaldehyde.
摘要：
Formaldehyde, which is well known as a toxic gas and an exogenous compound, is also produced endogenously via cytochrome P450 (CYP) mediated demethylation of compounds containing the CH3N or CH3O functionality. As the similarity to the accepted novel signaling molecules endogenous nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S), we hypothesized that endogenous formaldehyde may be another novel signaling molecule. We first compared the three signaling molecules to give the minimal sense criteria for signaling molecule. Formaldehyde fits with all the criteria. We also proposed the possible roles of endogenous formaldehyde in order to give a basis for further study. Formaldehyde may regulate NO level, can influence the structure of macromolecules such as DNA and proteins at molecular level. This hypothesis may start a new direction in the further study on endogenous formaldehyde.
作者机构：
[邱保胜] Cent China Normal Univ, Coll Life Sci, Wuhan 430079, Peoples R China.;Nanjing Univ, Coll Life Sci, Nanjing 210093, Peoples R China.
通讯机构：
[Qiu, BS] C;Cent China Normal Univ, Coll Life Sci, Wuhan 430079, Peoples R China.
关键词：
photoperiod-sensitive genic male-sterile rice;Nongken 58S;JIP test;photoinhibition;reaction center inactivation;D1 protein turnover;xanthophylls cycle
摘要：
The diurnal photosynthesis and photoinhibition in the photoperiod-sensitive genic male-sterile rice (Oryza sativa L.), Nongken 58S (NK58S), were investigated in this paper. From 06:00 to 09:00, no remarkable photoinhibition occurred, and the down-regulation of photosynthesis might be due to the running of xanthophylls cycle. From 10:00 to 12:00, the specific energy flux for dissipation (DIo/RC) and the net rate of reaction centers (RCs) closure (dV/dto) were increased, while the probability of electron transport at the acceptor side (yo) and the density of active RCs (Do) were decreased. These indicated that the photoinhibition of NK58S was exacerbated with the inactivation of PSⅡ RCs. Fluorescence dark relaxation analysis and inhibitor treatment suggested that all of state transition, xanthophyll cycle and inactivation of PSⅡ RCs could contribute to protect NK58S against photodamage. Compared with the inactivation of PSⅡRCs, xanthophyll cycle had an immediate response to high light stress, which functioned mainly in the period of relatively low light intensity. However, the inactivation of PSⅡ RCs played an important role in protecting the remaining active RCs when xanthophyll cycle was saturated.
