Governmental policies drive the LUCC trajectories in the Jianghan Plain
作者：
Wang, Hongzhi* ;Shao, Qihui;Li, Rendong;Song, Mingjie;Zhou, Yong
期刊：
Environmental Monitoring and Assessment ,2013年185(12):10521-10536 ISSN：0167-6369
通讯作者：
Wang, Hongzhi
作者机构：
[Zhou, Yong; Shao, Qihui; Wang, Hongzhi; Song, Mingjie] Cent Normal Univ, Fac Urban & Environm Sci, Wuhan 430079, Hubei Province, Peoples R China.;[Li, Rendong] Chinese Acad Sci, Inst Geodesy & Geophys, Wuhan 430077, Hubei Province, Peoples R China.
通讯机构：
[Wang, Hongzhi] C;Cent Normal Univ, Fac Urban & Environm Sci, Wuhan 430079, Hubei Province, Peoples R China.
关键词：
Jianghan Plain;LUCC;Change trajectories;Green policy;Rise of Central China Strategy;Grain Direct Subsidy Policy
摘要：
The prosperity of farmers is closely tied to governmental policies. The Jianghan Plain is an important region for commodity grains, cotton and edible oil for China. The trajectories of land use and land cover change (LUCC) of the study area from 1995 to 2010 were studied based on the LUCC database of the Chinese Academy of Sciences. The LUCC was characterised by a continuous decrease of arable land and continuous increase of waters and construction land. The LUCC was obviously concurrent with the implementation of related national policies. The transition to construction land was ever well controlled by 'Notice regarding the further strengthening of land management and arable land protection' promulgated in 1997. However, it flourished again with the 'Rise of Central China Strategy' taking effect since 2006. The transition of construction land to others reflects an uncommon trend, which must be strengthened with the strict implementation of the overall plan, which imposes a limited acreage quota of construction land to each district. The policies were quite contradictory to the transition of waters. LUCC related to waters is most active, which was driven by both natural forces and national policies. Just after the devastating flood of 1998, the state council of China put forward the Green Policy to govern the major rivers. As to the study area, it is mainly to 'push over dykes to let flood through and return farmland to lakes'. In 2004, the Grain Direct Subsidy Policy was implemented, which, along with the surge in the price of rice, resulted in a strengthening trend of conversion of ponds to paddy fields. © 2013 Springer Science+Business Media Dordrecht.
语种：
英文
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Aging-associated excess formaldehyde leads to spatial memory deficits
作者：
Tong, Zhiqian;Han, Chanshuai;Luo, Wenhong;Li, Hui;Luo, Hongjun;...
期刊：
Scientific Reports ,2013年3(1):1807 ISSN：2045-2322
通讯作者：
Cui, Dehua
作者机构：
[Su, Tao; Wu, Beibei; He, Rongqiao; Qiang, Min; Liu, Ying; Tong, Zhiqian; Han, Chanshuai] Chinese Acad Sci, Inst Biophys, State Key Lab Brain & Cognit Sci, Beijing 100101, Peoples R China.;[Luo, Hongjun; Li, Hui; Luo, Wenhong] Shantou Univ, Coll Med, Cent Lab, Shantou 515041, Guangdong, Peoples R China.;[Yang, Xu] Huazhong Normal Univ, Lab Environm Sci, Wuhan 430079, Peoples R China.;[Su, Tao; Wu, Beibei; Qiang, Min; Han, Chanshuai] Grad Univ, Chinese Acad Sci, Beijing 100049, Peoples R China.;[Wan, You; Tong, Zhiqian; Cui, Dehua] Peking Univ, Neurosci Res Inst, Beijing 100191, Peoples R China.
通讯机构：
[Cui, Dehua] P;Peking Univ, Neurosci Res Inst, Beijing 100191, Peoples R China.
摘要：
Recent studies show that formaldehyde participates in DNA demethylation/methylation cycle. Emerging evidence identifies that neuronal activity induces global DNA demethylation and re-methylation; and DNA methylation is a critical step for memory formation. These data suggest that endogenous formaldehyde may intrinsically link learning-responsive DNA methylation status and memory formation. Here, we report that during spatial memory formation process, spatial training induces an initial global DNA demethylation and subsequent re-methylation associated with hippocampal formaldehyde elevation then decline to baseline level in Sprague Dawley rats. Scavenging this elevated formaldehyde by formaldehyde-degrading enzyme (FDH), or enhancing DNA demethylation by a DNA demethylating agent, both led to spatial memory deficits by blocking DNA re-methylation in rats. Furthermore, we found that the normal adult rats intrahippocampally injected with excess formaldehyde can imitate the aged-related spatial memory deficits and global DNA methylation decline. These findings indicate that aging-associated excess formaldheyde contributes to cognitive decline during aging.
语种：
英文
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Intraperitoneal injection of magnetic Fe3O4-nanoparticle induces hepatic and renal tissue injury via oxidative stress in mice
作者：
Ma, Ping;Luo, Qing;Chen, Jiaoe;Gan, Yaping;Du, Juan;...
期刊：
INTERNATIONAL JOURNAL OF NANOMEDICINE ,2012年7:4809-4818 ISSN：1178-2013
通讯作者：
Yang, Xu
作者机构：
[Chen, Jiaoe; Gan, Yaping; Ma, Ping] Hubei Univ Sci & Technol, Coll Basic Med Sci, Xianning, Peoples R China.;[Luo, Qing; Yang, Xu; Du, Juan; Ma, Ping; Ding, Shumao] Cent China Normal Univ, Coll Life Sci, Hubei Key Lab Genet Regulat & Integrat Biol, Wuhan, Peoples R China.;[Xi, Zhuge] Tianjin Inst Hlth & Environm Med, Tianjin, Peoples R China.;[Yang, Xu] Huazhong Normal Univ, Coll Life Sci, Lab Environm Sci, Bldg 5,152 Luo Yu Rd, Wuhan 430079, Peoples R China.
通讯机构：
[Yang, Xu] H;Huazhong Normal Univ, Coll Life Sci, Lab Environm Sci, Bldg 5,152 Luo Yu Rd, Wuhan 430079, Peoples R China.
关键词：
8-hydroxy-2'-deoxyguanosine;DNA-protein crosslinks;Fe3O4-nanoparticles;glutathione;malondialdehyde;reactive oxygen species
摘要：
Because of its unique magnetic properties, the iron oxide (Fe3O4) nanoparticle has been widely exploited and its application in various fields has promised immense benefits. However, doubts exist over the use of Fe3O4-nanoparticles in human beings. Thus, the aim of the current study was to find out the potential safety range of medical use. Twenty-five Kunming mice were exposed to Fe3O4-nanoparticles via intraperitoneal injection daily for 1 week at doses of 0, 5, 10, 20, and 40 mg/kg. Hepatic and renal tissues were sliced for physiological observation. Injuries were observed in the high-dose groups (20 and 40 mg/kg) compared with the control group (0 mg/kg). Biomarkers of reactive oxygen species, glutathione, malondialdehyde, DNA-protein crosslinks, and 8-hydroxy-2′-deoxyguanosine in the hepatic and renal tissues were detected. Injury to tissues and oxidative damage to cells at the molecular level was found. The safest dose recommended from the results of this study is 5 mg/kg, as we believe this to be an upper limit balancing the benefits and risks for sub-long-term exposure. © 2012 Ma et al, publisher and licensee Dove Medical Press Ltd.
语种：
英文
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Adjuvant effects of gaseous formaldehyde on the hyper-responsiveness and inflammation in a mouse asthma model immunized by ovalbumin
作者：
Liu, Dandan;Zheng, Yuduo;Li, Bing;Yao, Hanchao;Li, Rui;...
期刊：
Journal of Immunotoxicology ,2011年8(4):305-314 ISSN：1547-691X
通讯作者：
Yang, Xu
作者机构：
[Yao, Hanchao; Liu, Dandan; Li, Rui; Yang, Xu; Li, Bing; Zheng, Yuduo] Huazhong Normal Univ, Lab Environm Sci, Wuhan 430079, Peoples R China.;[Zhang, Yinping] Tsinghua Univ, Dept Bldg Sci, Beijing 100084, Peoples R China.;[Yang, Xu] Huazhong Normal Univ, Hubei Key Lab Genet Regulat & Integrat Biol, Bldg 5,152 Luo Yu Rd, Wuhan 430079, Peoples R China.
通讯机构：
[Yang, Xu] H;Huazhong Normal Univ, Hubei Key Lab Genet Regulat & Integrat Biol, Bldg 5,152 Luo Yu Rd, Wuhan 430079, Peoples R China.
关键词：
Formaldehyde;asthma;airway hyper-responsiveness;pulmonary histopathology;eosinophil;IL-4;IL-6;IFN gamma
摘要：
Asthma is a complex pulmonary inflammatory disease, which is characterized by airway hyper-responsiveness, airflow obstruction, and airway inflammation. Exposure to a number of chemicals including formaldehyde (FA) can lead to asthma. This study aimed to explore the underlying role of FA exposure in occupational asthma, especially when it is combined with allergen exposure. Balb/c mice were randomly divided into six groups (n=6/group): (1) saline control; (2) ovalbumin (OVA)-immunized (OVAimm) only; (3) 0.5mg FA/m 3 exposure; (4) OVAimm+0.5mg FA/m 3 ; (5) 3.0mg FA/m 3 FA exposure; and, (6) OVAimm+3.0mg FA/m 3 . These low and high exposure FA levels were adopted from current (0.5mg/m 3 ) and original (3.0mg/m 3 ) Chinese Occupational Threshold Limit Values. Experiments were conducted after 3 week of combined exposure and a 1-week challenge with aerosolized OVA. Airway hyper-responsiveness, pulmonary tissue damage, eosinophil infiltration, and increased interleukin (IL)-4 and IL-6 levels in lung tissues were found in the OVA+3.0mg FA/m 3 hosts as compared to values seen in the OVA-immunized only mice. The results here suggest to us that FA exposure can induce and aggravate asthma in Balb/c mice when it is combined with OVA immunization. © 2011 Informa Healthcare USA, Inc.
语种：
英文
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Induction of GSNO reductase but not NOS in the lungs of mice exposed to glucan-spiked dust
作者：
Cao, Yi;Liang, Sisi;Zheng, Yuduo;Liu, Dandan;Zhang, Benyan;...
期刊：
ENVIRONMENTAL TOXICOLOGY ,2011年26(3):279-286 ISSN：1520-4081
通讯作者：
Yang, Xu
作者机构：
[Liu, Dandan; Liang, Sisi; Yang, Xu; Cao, Yi; Zheng, Yuduo] Huazhong Normal Univ, Coll Life Sci, Lab Environm Sci, Wuhan 430079, Peoples R China.;[Liu, Dandan; Liang, Sisi; Yang, Xu; Cao, Yi; Zheng, Yuduo] Huazhong Normal Univ, Coll Life Sci, Hubei Key Lab Genet Regulat & Integrat Biol, Wuhan 430079, Peoples R China.;[Zhang, Benyan] Wuhan Univ Sci & Technol, Coll Med, Dept Environm & Occupat Hlth, Wuhan 430065, Peoples R China.;[Xu, Dongqun] China Natl Ctr Dis Control & Prevent, Inst Environm Hlth & Related Prod Safety, Beijing 100021, Peoples R China.
通讯机构：
[Yang, Xu] H;Huazhong Normal Univ, Coll Life Sci, Lab Environm Sci, Wuhan 430079, Peoples R China.
关键词：
glucan-spiked dust;GSNO reductase;nitric oxide;NOS
摘要：
Both in vivo and in vitro studies have suggested that airborne organic dusts may induce inflammatory responses in the lungs, characterized by typical patterns of cytokine up-regulation and secretion. Recent work showed that exposure to glucan-spiked dust might influence nasal and pulmonary function, without an accompanying inflammatory response. However, effects of glucan-spiked dust exposure on NOS and GSNO reductase (enzymes important to NO signaling) remain less clear. This study aims to determine the effects of simultaneous exposure to glucan-spiked dust on NO signaling pathway in the airway. Danish Office dust was spiked with 1% (1-3)-β-glucan (curdlan). Mice were exposed to 20 μL PBS (controls), 20 μL 25 μg/20 μL OVA and 20 μL 100 μg/20 μL glucan-spiked dust, respectively, daily for 12 days. NOS and GSNO reductase activity were measured in lung homogenate. Glutathione concentration and SOD activity in lung tissue were also determined to evaluate changes in oxidative stress. IL-6 concentration was measured in lungs to quantify the inflammatory response. Results showed that 12 day OVA and glucan-spiked dust exposure did not significantly influence NOS activity, GSH concentration, SOD activity, or IL-6 concentration. An insignificant increase in GSNOR activity and expression was observed in 12 day OVA-exposed mice, whereas glucan-spiked dust exposure significantly increased GSNOR activity and expression. Our results suggested that repeated glucan-spiked dust exposure to the airway could activate GSNO reductase but not NOS. Since GSNO reductase plays a pivotal role in NO signaling, these results may have clinical importance. © 2009 Wiley Periodicals, Inc.
语种：
英文
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盐酸头孢噻呋对苦参碱大鼠体内药动学的影响
作者：
赵晨光;左华;廖丹丹;何小燕;李逐波
期刊：
中国中药杂志 ,2010年35(14):1859-1861 ISSN：1001-5302
通讯作者：
Zhao, C.
作者机构：
华中师范大学城市与环境科学学院;[左华] 左华;[李逐波] 李逐波;[赵晨光] 赵晨光;[廖丹丹] 廖丹丹
通讯机构：
College of Pharmaceutical Sciences, Southwest University, China
关键词：
苦参碱;盐酸头孢噻呋;药代动力学;药物相互作用
摘要：
目的:研究盐酸头孢噻呋对苦参碱在大鼠体内药动学的影响.方法:采用HPLC-UV测定苦参碱单独给药组与盐酸头孢噻呋和苦参碱联合给药组中苦参碱在大鼠体内的血药浓度, 用DAS2.1.、1药动学程序处理苦参碱的血药浓度一时间数据对, 比较两者的药动学参数.结果:苦参碱单独给药组苦参碱的C_(mar)为21. 113 9 mg.L~(-1), T_(mar)为0.75h, t_(1/2a)为1.34h, t_(1/2a)为3.509h, AUC_(o_t)为90. 984mg.h~(-1).L~(-1), AUC_(0_x)为100.346mg.h~(-1).L~(-1).盐酸头孢噻呋和苦参碱联合给药组苦参碱的C_(max)为11. 707mg'L~(-1)T_(max)为0.917h, t_(l/2a)为1.598h, t_(1/2a)为3.247h, AUC_(o-t)为53.28mg.h~(-l).L~(-1), AUC_(o_x)为60.035 mg'h~(-1).L~(-1)结论:苦参碱与盐酸头孢噻呋联合给药时苦参碱的血药浓度、生物利用度显著降低, 在外周室的分布减少, 中央室的努布增加, 体内清除率亦有所增加.
语种：
中文
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On the intensity and type transition of land use at the basin scale using RS/GIS: A case study of the Hanjiang River Basin
作者：
Yu, Guangming
* （ ;Zeng, Qun;Yang, Shan;Hu, Limei;Lin, Xiaowei;...
期刊：
Environmental Monitoring and Assessment ,2010年160(1-4):169-179 ISSN：0167-6369
通讯作者：
Yu, Guangming
（ 作者机构：
[Yu, Guangming; Zeng, Qun; Hu, Limei; Lin, Xiaowei; Che, Yi; Zheng, Yuge; Yang, Shan] Cent China Normal Univ, Coll Urban & Environm Sci, Wuhan 430079, Peoples R China.
通讯机构：
[Yu, Guangming] C;Cent China Normal Univ, Coll Urban & Environm Sci, Wuhan 430079, Peoples R China.
关键词：
Land use;Land use structure;Intensity coefficient;Rate of change in double-directions;RS/GIS
摘要：
The purpose of this study is to investigate the land use intensity and land use change type at the basin scale in the middle and lower reaches of the Hanjiang River Basin (in Hubei Province, China) by combining the Landsat TM images in 1995 and 2000 with the land use database (in scale 1:10,000) and relative data. In this study, the basic data is acquired from the interpretation of remote sensing (RS) images. The intensity of land use and the rate of change in double-directions of land use dynamics are calculated with the support of software ARC/INFO. The intensity of land use is indicated by the intensity coefficient of land use, and the transition of land use types is quantified as the rate of change in double-direction of land use types and also expressed as the transition matrix of land use types. The results are expressed in space by Geographic Information System (GIS) software. Results of this study show that (1) the intensity of land use is high in the study region, the intensity coefficients of land use in 1995 and 2000 are 260.025 and 290.526, respectively, and the intensity of development and utilization of land is trend to increscent; and (2) the rate of land use change in double directions in the whole study region is 0.52 with great spatial variation and the differentiation of land use types. In the differentiation of land use types, the unutilized land (with the rate to 4.391) is developed fast, the grassland (with 2.836) and water area (with 1.664) are disturbed severely, and these changes will influence the eco-environment in the Hanjiang River Basin and all the Yangtze Basin. The rates of the farmland and the woodland are 0.424 and 0.344, respectively, meaning that the fundamentals of regional human-environmental system are relative stable. With this study, we can conclude that (1) the patterns of land use are increasingly changing in the study region, the environmental impacts are escalated on this stage, and the further outcomes are destined to change the stability of the regional human-environmental system; and (2) the most useful method to study the present land use and its change is through the use of the RS/GIS with the land use database (in scale 1:10,000). © 2008 Springer Science+Business Media B.V.
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英文
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Phytotoxic effects of cyanobacteria extract on Lemna minor and Myriophyllum spicatum phyto-tolerance and superoxide dismutase activity
作者：
Ding Yi;Zhao Yijun;Bai Xue;Fang Zhihui;Cheng Kai*
期刊：
ENVIRONMENTAL TOXICOLOGY ,2009年24(3):304-308 ISSN：1520-4081
通讯作者：
Cheng Kai
作者机构：
[Ding Yi; Cheng Kai; Zhao Yijun; Bai Xue; Fang Zhihui] Cent China Normal Univ, Hubei Key Lab Urban Environm Ecol, Wuhan 430079, Peoples R China.
通讯机构：
[Cheng Kai] C;Cent China Normal Univ, Hubei Key Lab Urban Environm Ecol, Wuhan 430079, Peoples R China.
关键词：
microcystin;Lemna minor;Myriophyllum spicatum;SOD;CAT
摘要：
The research on the effects of microcystins on aquatic plants has increased. Some aquatic plants have some tolerance to microcystins but the mechanism of the tolerance is still unknown. In this experiment, we used microcystins of different concentrations to study the toxic effect in Lemna minor and Myriophyllum spicatum. Experiments were carried out with a range of microcysitns levels (equivalent to 0, 0.1, 0.5, 1.0, and 4.3 mg/L). The growth of L. minor (as fresh weight) and chlorophyll a content were significantly reduced and superoxide dismutase (SOD) activity was significantly decreased at microcystins concentration up to 0.5 mg/L. The growth of M. spicatum was affected, only weakly, by microcystins and 0.5 mg/L and these treatments caused significant decrease in chlorophyll a content. Besides, the SOD activity of M. spicatum positively correlated to microcystins concentration (P < 0.01). The result indicated that M. spicatum was more tolerant to microcystins than L. minor and the induced SOD activity may contribute to the tolerance. The experiment also indicated that catalase (CAT) activity was not significantly influenced by microcystin for both the two tested aquatic plants. © 2008 Wiley Periodicals, Inc.
语种：
英文
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Impacts of cage-culture of Oreochromis niloticus on organic matter content, fractionation and sorption of phosphorus, and alkaline phosphatase activity in a hypereutrophic lake, People's Republic of China
作者：
Zhang, M;Zhou, Y* ;Xie, P;Xu, J;Li, J;...
期刊：
Bulletin of Environmental Contamination and Toxicology ,2004年73(5):927-932 ISSN：0007-4861
通讯作者：
Zhou, Y
作者机构：
[Zhou, Y] Chinese Acad Sci, Inst Hydrobiol, Donghu Lake Ecosyst Expt Stn, Wuhan 430072, Peoples R China.;Huazhong Normal Univ, Coll Resources & Environm, Wuhan 430070, Peoples R China.;Nanjing Agr Univ, Coll Resources & Environm Sci, Nanjing 210095, Peoples R China.
通讯机构：
[Zhou, Y] C;Chinese Acad Sci, Inst Hydrobiol, Donghu Lake Ecosyst Expt Stn, Wuhan 430072, Peoples R China.
摘要：
No abstract available
语种：
英文
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铜对大叶相思-根瘤菌共生固氮体系的影响
作者：
聂湘平;蓝崇钰;张志权;束文圣;黄铭洪
期刊：
应用生态学报 ,2002年13(2):137-140 ISSN：1001-9332
作者机构：
中山大学生命科学学院,广州,510275;香港浸会大学生物系,香港,九龙塘;[聂湘平; 蓝崇钰; 张志权; 束文圣] 中山大学;[黄铭洪] 香港浸会大学
关键词：
铜;根瘤菌;大叶相思;生长;结瘤;固氮酶活性
摘要：
报道了两种根瘤菌(大叶相思、美丽胡枝子)对Cu2+的耐受性以及植物-根瘤菌共生固氮体系在Cu2+胁迫下结瘤、固氮和生长的变化,讨论了大叶相思在矿山尾矿废弃地作为先锋植物结瘤固氮的可能性.结果表明,大叶相思根瘤菌对Cu2+离子的耐受性较强,可以耐受Cu2+＜0.80mmol的离子浓度,Cu2+对它的半致死浓度为0.129mmol.在无菌砂培无重金属影响条件下,其固氮酶活性为2.7 C2H4*μg*g-1*h-1,当Cu2+>0.125mmol会导致大叶相思固氮酶活性急剧下降,其有效半抑制浓度(EC50)为0.151mmol,Cu2+为0.50mmol完色抑制大叶相思固氮酶活性,不阻碍结瘤,但严重抑制植物生长发育,引起植物叶片白化、植株矮化.在外加N源不接菌和不加N源接菌两种处理组间,Cu2+＜0.125mmol时,以不加N接菌处理对大叶相思生长有利.大叶相思对Cu2+吸收积累根部高于地上组织.
语种：
中文
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