作者机构：
[Yang, Jiao-Yan] Cent China Normal Univ, Coll Life Sci, Wuhan 430079, Peoples R China.;[Lu, Liang-Qiu; Ming, Zhi-Hui; An, Jing; Hua, Qiu-Lin] Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticides & Chem Biol, Wuhan 430079, Peoples R China.
通讯机构：
[Lu, Liang-Qiu] C;Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticides & Chem Biol, Wuhan 430079, Peoples R China.
摘要：
The crystal structure of the title compound, C14H11NO4, is influenced by N - H⋯O and O - H⋯O hydrogen bonds, linking mol-ecules into one-dimensional tapes running along the [010] direction.
摘要：
<正>Listeria monocytogenes is able to efficiently utilize glycerol as carbon source.In a defined minimal medium the growth rate is similar(during balanced growth) in presence of glycerol as in presence
通讯机构：
[Li, Xue-Bao] H;Hua Zhong Normal Univ, Hubei Key Lab Genet Regulat & Integrat Biol, Coll Life Sci, Wuhan 430079, Peoples R China.
摘要：
Fasciclin-like arabinogalactan proteins (FLAs), a subclass of arabinogalactan proteins (AGPs), are usually involved in cell development in plants. To investigate the expression profiling as well as the role of FLA genes in fiber development, 19 GhFLA genes (cDNAs) were isolated from cotton (Gossypium hirsutum). Among them, 15 are predicted to be glycosylphosphatidylinositol anchored to the plasma membranes. The isolated cotton FLAs could be divided into four groups. Real-time quantitative reverse transcriptase polymerase chain reaction results indicated that the GhFLA genes are differentially expressed in cotton tissues. Three genes (GhFLA1/2/4) were specifically or predominantly expressed in 10 days post-anthesis fibers, and the transcripts of the other four genes (GhFLA6/14/15/18) were accumulated at relatively high levels in cotton fibers. Furthermore, expressions of the GhFLA genes are regulated in fiber development and in response to phytohormones and NaCl. The identification of cotton FLAs will facilitate the study of their roles in cotton fiber development and cell wall biogenesis.
作者机构：
College of Life Science, Central China Normal University, Wuhan 430079
会议名称：
第十届室内空气品质和质量国际学术会议(Proceedings of the 10th International Conference on Indoor Air Quality and Climate)
会议时间：
2005-09-04
会议地点：
北京
会议论文集名称：
第十届室内空气品质和质量国际学术会议
关键词：
Formaldehyde;Toxicological study;Physiological study
摘要：
This paper is a review on recent developments of the toxicological and physiological studies on formaldehyde.Hotspots involved in this topic include: (1) Formaldehyde-induced gene expression; (2) Formaldehyde-induced asthma; (3) Airway neurogenic inflammation (4) formaldehyde working as signaling molecule in body;, (5)Epigenesis: methylation of DNA and proteins; (6) DNA-protein crosslink; (7) Lysine-DPC repair enzyme; (8)Formaldehyde-induced Apoptosis.
作者机构：
College of Life Science, Central China Normal University (CCNU);College of Life Science, Central China Normal University (CCNU) State Key Laboratory of Virology, Wu;Key Laboratory of Pesticide & Chemical Biology of Ministry of Education, College of Chemistry (CCNU)
会议名称：
The 2nd International Conference on Bioinformatics and Biomedical Engineering(iCBBE 2008)(第二届生物信息与生物医学工程国际会议)
会议时间：
2008-05-16
会议地点：
上海
会议论文集名称：
The 2nd International Conference on Bioinformatics and Biomedical Engineering(iCBBE 2008)(第二届生物信息与生物医学工程国际会议)论文集
摘要：
Rice blast, caused by the ascomycete fungus Magnaporthe grisea, is one of the most serious diseases for cultivated rice. Sterol 14α-demethylase (CYP51) is one of the key enzymes of sterol biosynthesis in biological kingdoms and an important drug target for microbial pathogenic infections. In the present study CYP51 with truncation of N-terminal residues from M. grisea (MGCYP51) was cloned and expressed in E. coli, drug binding spectrum of MGCYP51 induced by addition of diniconazole was determined. In order to exploit more selective and effective fungicides for M. grisea, homology model of MGCYP51 was established based on crystal structure of Mycobacterium tuberculosis and diniconazole was docked into the active site by FlexX. The spectral data showed that diniconazole exhibited a high affinity for MGCYP51, coincided with the implication of molecular docking. The results in a way elucidated the reasonability and reliability of the 3D model and docking model, which can be hopefully used to virtually screen the more potent azole fungicides for MGCYP51.
