摘要：
Previous studies have found working memory (WM) advantages of the pathological smartphone use (PSU) group, but most of which were emphasized in the network-related domain. Whether the advantages can transfer to other domains has yet to be confirmed. In particular, exploring from a brain mechanism perspective is necessary. Using the classical N-back paradigm, this study selected network-related words and neutral words as materials combined with fNIRS to probe the verbal WM characteristics of the PSU group. The results showed that β in channel 3, channel 4, and channel 5 were significantly lower in the PSU group than those in the control group The analysis of the region of interest revealed that the PSU group showed significantly lower β in the l-DLPFC and frontopolar. Granger Causality results showed that functional connectivity between frontopolar and R-DLPFC for the PSU group was significantly higher than for the control group in the network word condition. These results demonstrate that the PSU group has an advantage in WM, transferring from the network-related stimulus to the neutral stimulus. The advantages of network stimulus were related to bidirectional connectivity between frontopolar and R-DLPFC. Also, the l-DLPFC and frontopolar are associated with the cross-material consistency of WM.
期刊：
Journal of Affective Disorders,2023年333:331-341 ISSN：0165-0327
通讯作者：
Chen, H
作者机构：
[Liu, Xinyuan; Chen, Ximei; Chen, Hong; Ling, Ying; Li, Wei; Liu, Yong; Zheng, Anqi] Minist Educ, Key Lab Cognit & Personal SWU, Chongqing 400715, Peoples R China.;[Liu, Xinyuan; Chen, Ximei; Chen, Hong; Ling, Ying; Li, Wei; Chen, H; Liu, Yong; Zheng, Anqi] Southwest Univ, Fac Psychol, 2 Tiansheng Rd, Chongqing 400715, Peoples R China.;[Li, Qingqing] Cent China Normal Univ, Sch Psychol, Wuhan, Peoples R China.;[Chen, Hong] Res Ctr Psychol & Social Dev, Chongqing 400715, Peoples R China.
通讯机构：
[Chen, H ] S;Southwest Univ, Fac Psychol, 2 Tiansheng Rd, Chongqing 400715, Peoples R China.
关键词：
Eating disorder symptoms;Fractional amplitude of low-frequency fluctuations;Functional connectivity;Resting-state fMRI;Type A personality
摘要：
BACKGROUND: Type A personality (TAP) was characterized by impatience, competitiveness, aggressiveness, and hostility. Higher TAP was proved to be associated with more eating disorder symptoms (EDS). While little is known about the underlying neural substrates of TAP and how TAP is linked to EDS at the neural level. METHODS: To investigate the neural basis of TAP, we adopted fractional amplitude of low-frequency fluctuations (fALFF) and resting-state functional connectivity (RSFC) via resting-state functional magnetic resonance imaging (rs-fMRI) (N=1620). Mediation models were examined to explore the relationship between TAP, EDS, and brain activity. RESULTS: TAP was associated with decreased fALFF in the left middle frontal gyrus (MFG) and increased fALFF in the left precentral gyrus (PreCG). Furthermore, TAP was positively correlated to RSFC between the left MFG and left inferior temporal gyrus (ITG) and between the left PreCG and right middle temporal gyrus (MTG). Mediation analysis showed TAP fully mediated the association of the left MFG activity, MFG-ITG connectivity, and PreCG-MTG connectivity with EDS. LIMITATIONS: The cross-sectional design of this study precludes us from specifying the causal relationship in the associations we observed. CONCLUSIONS: Our results suggested spontaneous activity in the left MFG and PreCG is associated with TAP, and even in general sample, people with higher TAP showed more EDS. The present study is the first to investigate the neurobiological underpinnings of TAP in a large sample and further offered new insights into the relation between TAP and EDS from a neural basis perspective.
摘要：
The prevalence of the novel coronavirus (COVID-19) has been considered a major threat to physical and mental health around the world, causing great pressure and mortality threat to most people. The current study aimed to investigate the neurological markers underlying the relationship between perceived mortality threat (PMT) and negative affect (NA). We examined whether the regional amplitude of low-frequency fluctuations (ALFF) and resting-state functional connectivity (RSFC) before the COVID-19 outbreak (October 2019 to December 2019, wave 1) were predictive for NA and PMT during the mid-term of the COVID-19 pandemic (February 22 to 28, 2020, wave 2) among 603 young adults (age range 17-22, 70.8% females). Results indicated that PMT was associated with spontaneous activity in several regions (e.g., inferior temporal gyrus, medial occipital gyrus, medial frontal gyrus, angular gyrus, and cerebellum) and their RSFC with the distributed regions of the default mode network and cognitive control network. Furthermore, longitudinal mediation models showed that ALFF in the cerebellum, medial occipital gyrus, medial frontal gyrus, and angular gyrus (wave 1) predicted PMT (wave 2) through NA (wave 2). These findings revealed functional neural markers of PMT and suggest candidate mechanisms for explaining the complex relationship between NA and mental/neural processing related to PMT in the circumstance of a major crisis.(c) 2023 IBRO. Published by Elsevier Ltd. All rights reserved.
通讯机构：
[Ma, HY ] C;Cent China Normal Univ, Sch Psychol, Wuhan 430079, Peoples R China.;Minist Educ, Key Lab Adolescent Cyberpsychol & Behav CCNU, Wuhan 430079, Peoples R China.
关键词：
problem-solving demands;thriving at work;challenge appraisal;hindrance appraisal;organizational identity
摘要：
In globalized markets, it is important for companies to cultivate a thriving workforce that is motivated to grow and develop. Based on the transactional theory of stress, we discussed how the way people appraise their problem-solving demands, either as a challenge or a hindrance, impacts employees’ thriving at work. Data were collected from employees of a state-owned enterprise in China at two separate points with a 4-week interval. The results showed that problem-solving demands have a positive impact on employees’ thriving at work through challenge appraisal and a negative impact on employees’ thriving at work through hindrance appraisal. Additionally, we observed a moderated mediation effect in which organizational identity strengthened the positive effects of problem-solving demands on challenge appraisal, which in turn promoted employees’ thriving at work. The findings highlight the role of cognitive appraisal in interpreting employees’ responses to work stress.
期刊：
PHYSICAL CHEMISTRY CHEMICAL PHYSICS,2023年26(1):130-143 ISSN：1463-9076
通讯作者：
Zhao, YJ
作者机构：
[Zhao, Yunjie; Zeng, Chengwei; Li, Anbang; Zhuo, Chen] Cent China Normal Univ, Inst Biophys, Wuhan 430079, Peoples R China.;[Zhao, Yunjie; Zeng, Chengwei; Li, Anbang; Zhuo, Chen] Cent China Normal Univ, Dept Phys, Wuhan 430079, Peoples R China.;[Jian, Yiren] Dartmouth Coll, Dept Comp Sci, Hanover, NH 03755 USA.;[Zeng, Chen] George Washington Univ, Dept Phys, Washington, DC 20052 USA.
通讯机构：
[Zhao, YJ ] C;Cent China Normal Univ, Inst Biophys, Wuhan 430079, Peoples R China.;Cent China Normal Univ, Dept Phys, Wuhan 430079, Peoples R China.
摘要：
Biological processes such as transcription, repair, and regulation require interactions between DNA and proteins. To unravel their functions, it is imperative to determine the high-resolution structures of DNA-protein complexes. However, experimental methods for this purpose are costly and technically demanding. Consequently, there is an urgent need for computational techniques to identify the structures of DNA-protein complexes. Despite technological advancements, accurately identifying DNA-protein complexes through computational methods still poses a challenge. Our team has developed a cutting-edge deep-learning approach called DDPScore that assesses DNA-protein complex structures. DDPScore utilizes a 4D convolutional neural network to overcome limited training data. This approach effectively captures local and global features while comprehensively considering the conformational changes arising from the flexibility during the DNA-protein docking process. DDPScore consistently outperformed the available methods in comprehensive DNA-protein complex docking evaluations, even for the flexible docking challenges. DDPScore has a wide range of applications in predicting and designing structures of DNA-protein complexes. Biological processes such as transcription, repair, and regulation require interactions between DNA and proteins.
摘要：
Time pressure affects multiple cognitive processes but how it affects attention capture remains unclear. Two experiments were carried out in the present study to assess whether time pressure prevents attention from capturing by salient distractors and explore the underlying neural mechanisms using functional near-infrared spectroscopy. The results of behavioral tests showed that the singleton effect decreased (Experiment 2) or even disappeared (Experiment 1) when the subject was under time pressure. Neuroimaging data showed that under time pressure, a salient distractor elicited greater activation in the left middle frontal gyrus/inferior frontal gyrus and bilateral superior parietal lobule, brain areas that are thought to be involved in cognitive inhibition and control of spatial attentional shifts. These findings suggest that the reduction or disappearance of the singleton effect under time pressure results from enhanced inhibition of and/or accelerated disengagement from salient distractors.
期刊：
International Journal of Mental Health and Addiction,2023年21(6):3735-3748 ISSN：1557-1874
通讯作者：
Quanlei Yu
作者机构：
[Li, Junzhi; Zhang, Hongpo] Henan Univ Chinese Med, Mental Hlth Educ & Counseling Ctr, Zhengzhou, Peoples R China.;[Peng, Shun] Jianghan Univ, Sch Educ, Wuhan, Peoples R China.;[Li, Songqing; Yu, Quanlei] Cent China Normal Univ, Sch Psychol, Wuhan, Peoples R China.;[Yu, Quanlei] Minist Educ, Key Lab Modern Educ, Xian, Peoples R China.
通讯机构：
[Quanlei Yu] S;School of Psychology, Central China Normal University, Wuhan, China<&wdkj&>The Key Laboratory of Modern Education, Ministry of Education, Xi’an, China
关键词：
Online social support;Depressive symptoms;Self-esteem;Gender;Undergraduates
摘要：
Online communication has become an increasingly common phenomenon; however, the relationship between online social support and depressive symptoms and its mechanisms is unclear. This study aims to explore the mediating effect of self-esteem and the moderating effect of gender on the relationship between online social support and depressive symptoms. A total of 706 undergraduates completed anonymous questionnaires regarding online social support, self-esteem, and depressive symptoms. The results indicated that online social support was negatively associated with depressive symptoms and that self-esteem mediated the relationship between online social support and depressive symptoms. Moreover, gender moderated the first part of the mediation process, and the effect of online social support on self-esteem was more pronounced in the male group than in the female group. These findings can advance the understanding of how online social support is related to depressive symptoms, which has implications for the prevention and intervention of depressive symptoms in undergraduate students.
期刊：
International Journal of Environmental Research and Public Health,2023年20(2):1105- ISSN：1661-7827
通讯作者：
Junmei Xiong
作者机构：
[Xiong, Junmei; Xie, Weiwei; Zhang, Tong] Minist Educ, Key Lab Adolescent Cyberpsychol & Behav CCNU, Wuhan 430079, Peoples R China.;[Xiong, Junmei; Xie, Weiwei; Zhang, Tong] Cent China Normal Univ, Sch Psychol, Key Lab Human Dev & Mental Hlth Hubei Prov, Wuhan 430079, Peoples R China.;[Xiong, Junmei; Xie, Weiwei; Zhang, Tong] Cent China Normal Univ, Sch Psychol, Wuhan 430079, Peoples R China.
通讯机构：
[Junmei Xiong] K;Key Laboratory of Adolescent Cyberpsychology and Behavior (CCNU), Ministry of Education, Wuhan 430079, China<&wdkj&>School of Psychology, Central China Normal University, Wuhan 430079, China<&wdkj&>Key Laboratory of Human Development and Mental Health of Hubei Province, School of Psychology, Central China Normal University, Wuhan 430079, China<&wdkj&>Author to whom correspondence should be addressed.
关键词：
dual-factor model of mental health;cumulative risk;coping style;gratitude;left-behind children in China
摘要：
Based on the dual-factor model of mental health (DFM) and the cumulative risk (CR) model, this study aimed to investigate the impact of CR on left-behind children's mental health and the underlying mechanism involved, specifically the mediating role of coping style and the moderating role of gratitude in the relationship between CR and mental health. The random cluster sampling method was applied to collect data on CR, coping style, gratitude, life satisfaction, and depression from 705 left-behind children (374 boys, M-age = 12.20 +/- 1.25). The moderated mediation analyses indicated that: (1) the moderated mediation model of CR and depression was significant: coping style mediated the relationship between CR and depression, and gratitude moderated this mediating effect with gratitude strengthening the negative association between CR and coping style; and (2) gratitude moderated the relationship between CR and life satisfaction and it also strengthened the negative association between CR and life satisfaction. The findings suggest that the mechanisms of coping style may differ in the relationships between CR and positive and negative indicators of mental health in left-behind children and that gratitude as a protective factor has limited capacity to buffer the negative effect of accumulated risk. These findings provide evidence for differentiated intervention approaches to promote disadvantaged children's life satisfaction and depression.
摘要：
Previous research has presented conflicting evidence regarding whether Chinese characters are processed holistically. In past work, we applied Systems Factorial Technology (SFT) and discovered that native Chinese speakers exhibited limited capacity when processing characters and words. To pinpoint the source of this limitation, our current research delved further into the mental architecture involved in processing Chinese characters and English words, taking into consideration information from each component. In our current study, participants were directed to make the same/different judgments on characters/words presented sequentially. Our results indicated that participants utilized a parallel self-terminating strategy when both or neither of the left/right components differed (Experiment 1). Faced with the decisional uncertainty that either the left/right component would also differ, most participants processed with a parallel exhaustive architecture, while a few exhibited the coactive architecture (Experiment 2). Taken together, our work provides evidence that in word/character perception, there is weak holistic processing (parallel self-terminating processing) when partial information is sufficient for the decision; robust holistic processing (coactive or parallel exhaustive processing) occurs under decisional uncertainty. Our findings underscore the significant role that the task and presentation context play in visual word processing.
期刊：
Journal of Hazardous Materials,2023年457:131837 ISSN：0304-3894
通讯作者：
Lu, C
作者机构：
[Liu, Zijing; Yang, Wenhui; Lu, Chan; Liao, Hongsen] Cent South Univ, XiangYa Sch Publ Hlth, Changsha 410078, Hunan, Peoples R China.;[Wang, Faming] Katholieke Univ Leuven, Dept Biosyst, Div Anim & Human Hlth Engn, B-3001 Leuven, Belgium.;[Wang, Faming] Xian Univ Sci & Technol, Occupat Safety & Publ Hlth Grp, Xian 710054, Shanxi, Peoples R China.;[Li, Bin] Cent China Normal Univ, Sch Psychol, Wuhan 430070, Hubei, Peoples R China.
通讯机构：
[Lu, C ] C;Cent South Univ, XiangYa Sch Publ Hlth, Changsha 410078, Hunan, Peoples R China.
关键词：
Childhood pneumonia;Gaseous air pollution;Particulate matters;Postnatal;Pregnancy
摘要：
BACKGROUND: Despite mounting evidence linked pneumonia with air pollution, it is unclear what main pollutant(s) exposure in which critical window(s) play a key role in pneumonia. OBJECTIVE: To examine effects of intrauterine and post-natal exposure to air pollution on children's doctor-diagnosed pneumonia (DDP). METHODS: A combination of cross-sectional and retrospective cohort study was conducted at Changsha, China during 2019-2020. Personal exposure to outdoor air pollutants at each child's home address was estimated using inverse distance weighted (IDW) method based on data from 10 air quality monitoring stations. Associations between personal air pollution exposure and DDP were evaluated. RESULTS: Children's DDP was associated with intrauterine and post-natal exposure to PM(2.5), PM(2.5-10), and PM(10), adjusted ORs (95% CI) of 1.17 (1.04-1.30), 1.09 (1.01-1.17), and 1.07 (1.00-1.14) for IQR increase in intrauterine exposure and 1.12 (1.02-1.22), 1.13 (1.06-1.21), and 1.28 (1.16-1.41) for post-natal exposure. Intrauterine PM(2.5) exposure and post-natal PM(10) exposure were associated with a higher risk of pneumonia. We identified the 2nd trimester, 3rd trimester, and first year as critical windows respectively for PM(2.5), PM(2.5-10), and PM(10) exposure. Daytime exposure to traffic-related air pollution especially during early life increased DDP. CONCLUSION: Intrauterine and post-natal exposure to particulate matters played a dominant role in children's DDP.
作者机构：
[Liu, Xue-Feng; Tan, Xin-Guan; Wang, Yu-Qing; Pang, Ming-Hui] Chengdu Univ Technol, Coll Math & Phys, Chengdu 610059, Peoples R China.;[Zhao, Yun-Jie; Zhao, YJ] Cent China Normal Univ, Inst Biophys, Wuhan 430079, Peoples R China.;[Zhao, Yun-Jie; Zhao, YJ] Cent China Normal Univ, Dept Phys, Wuhan 430079, Peoples R China.
通讯机构：
[Zhao, YJ ; Liu, XF ] C;Chengdu Univ Technol, Coll Math & Phys, Chengdu 610059, Peoples R China.;Cent China Normal Univ, Inst Biophys, Wuhan 430079, Peoples R China.;Cent China Normal Univ, Dept Phys, Wuhan 430079, Peoples R China.
关键词：
comprehensive molecular dynamics (MD) simulation;drug design;human serotonin transporter (SERT);molecular mechanics/generalized Born surface area (MM/GBSA) method
作者机构：
[Liu, Qinxue; Wu, Jiayin] Cent China Normal Univ, Sch Psychol, Wuhan, Peoples R China.;[Liu, Qinxue; Wu, Jiayin] Cent China Normal Univ, Key Lab Adolescent Cyberpsychol & Behav, Minist Educ, Wuhan, Peoples R China.;[Liu, Qinxue; Wu, Jiayin] Key Lab Human Dev & Mental Hlth Hubei Prov, Wuhan, Peoples R China.
关键词：
COVID-19;Depressive symptoms;College students;Latent growth curve model
摘要：
The ongoing COVID-19 pandemic is not only an immediate hazard but also a long-term risk to the development of depressive symptoms. However, it remains unclear how people's depressive symptoms change with the process of COVID-19. Further, there is also a paucity of research on the underlying antecedents and outcomes of depressive symptoms during this global health crisis. In this study, a longitudinal study was conducted in China and the data of 559 participants were collected from the outbreak period to the normalization period of the pandemic through self-report questionnaires. Depressive symptoms were longitudinally analyzed using Patient Health Questionnaire-9. Core variables involving society, family, individual cognition, and behaviors were studied as determinants or consequences. Latent growth curve model analyses indicated that college students had mild depressive symptoms at the initial stage of COVID-19 with a subsequent decreasing linear slope. Depressive symptoms were significantly predicted by college students' risk perception of COVID-19, social support, family functioning, and smartphone addiction tendency. Further, their depressive symptoms predicted the changes in smartphone addiction tendency and levels of hope. In conclusion, current findings can provide implications for future prevention and intervention of mental disorders to assist college students through such challenging times.
摘要：
Objectives: This study aimed to clarify the relationship between Mycoplasma pneumoniae (M. pneumoniae) and Kawasaki disease by conducting an updated systemic review and meta-analysis of published studies.Materials and methods: Studies mentioning M. pneumoniae and Kawasaki disease before October 2022 were included in this meta-analysis. The pooled prevalence was calculated, and the log odds ratio in the random effects model was applied to estimate the pooled prevalence of M. pneumoniae infection in pediatric patients with Kawasaki disease. In addition, the clinical parameters, such as hemoglobin and erythrocyte sedimentation rate, were analyzed. Six studies with a total of 1,859 pediatric patients with Kawasaki disease were enrolled. The focused outcome was the pooled prevalence and clinical parameters.Results: The pooled prevalence of M. pneumoniae infection was statistically significant in pediatric patients with Kawasaki disease. In addition, the values of hemoglobin and erythrocyte sedimentation rate were significantly different between M. pneumoniae-infected and non -M. pneumoniae- infected patients with Kawasaki disease. Other clinical parameters were not significantly different between M. pneumoniae-infected and non -M. pneumoniae-infected patients with Kawasaki disease. Conclusion: The results suggest that M. pneumoniae infection is significantly prevalent in pediatric patients with Kawasaki disease. The lower values of hemoglobin and erythrocyte sedimentation rate in M. pneumoniae-infected patients with Kawasaki disease might be needed to investigate further.
期刊：
International Journal of Mental Health and Addiction,2023年21(5):2824-2841 ISSN：1557-1874
通讯作者：
Quanlei Yu<&wdkj&>Qing Xiong
作者机构：
[Zheng, Xintong; Chen, Jianwen] Huazhong Univ Sci & Technol, Sch Educ, Wuhan 430074, Hubei, Peoples R China.;[Li, Congcong; Yu, Quanlei] Cent China Normal Univ, Sch Psychol, Wuhan 430079, Hubei, Peoples R China.;[Shi, Shuping] RDFZ Chaoyang Branch Sch, Beijing, Peoples R China.;[Yu, Quanlei] Minist Educ, Key Lab Adolescent Cyberpsychol & Behav CCNU, Wuhan, Peoples R China.;[Yu, Quanlei] Cent China Normal Univ Branch, Collaborat Innovat Ctr Assessment Basic Educ Qual, Wuhan, Peoples R China.
通讯机构：
[Quanlei Yu] S;[Qing Xiong] J;School of Psychology, Central China Normal University, Wuhan, China<&wdkj&>Key Laboratory of Adolescent Cyberpsychology and Behavior (CCNU), Ministry of Education, Wuhan, China<&wdkj&>Collaborative Innovation Center of Assessment Toward Basic Education Quality, Central China Normal University Branch, Wuhan, China<&wdkj&>Jiangxi University of Finance and Economics, Nanchang, China
关键词：
Stressful life events;Adolescents;Problematic Internet use;Self-worth orientation theory;Physical activity
期刊：
International Journal of Psychophysiology,2023年188:1-11 ISSN：0167-8760
通讯作者：
Ming Peng
作者机构：
[Peng, Ming; Chen, Tianlong; Yang, Xiaoying; Tang, Rui] Cent China Normal Univ, Sch Psychol, Minist Educ, Key Lab Adolescent Cyberpsychol & Behav, Wuhan, Peoples R China.;[Peng, Ming; Chen, Tianlong; Yang, Xiaoying; Tang, Rui] Cent China Normal Univ, Sch Psychol, 152 Luoyu Rd, Wuhan 430079, Hubei, Peoples R China.;[Peng, Ming] Key Lab Human Dev & Mental Hlth Hubei Prov, Wuhan 430079, Peoples R China.;[Cai, Mengfei] Manhattanville Coll, Dept Psychol, New York, NY USA.
通讯机构：
[Ming Peng] K;Key Laboratory of Adolescent Cyberpsychology and Behavior of the Ministry of Education and School of Psychology, Central China Normal University, Wuhan, China<&wdkj&>School of Psychology, Central China Normal University, Wuhan, China<&wdkj&>Key Laboratory of Human Development and Mental Health of Hubei Province, Wuhan 430079, China
关键词：
EEG;ERP;Fairness consideration;Moral transgression;Ultimatum game
摘要：
People tend to dislike and punish unfair behaviors in social interactions, and this disposition may be moderated by the characteristics of their interaction partner. We used a modified ultimatum game (UG) to investigate players' responses to fair and unfair offers from proposers described as having performed either a moral transgression or a neutral behavior, and recorded an electroencephalogram. The participants' behavior in the UG suggests that people quickly demand more fairness from proposers who have committed moral transgressions rather than neutral behavior. Event-related potentials (ERPs) revealed a significant effect of offer type and of proposer type on P300 activity. The prestimulus α-oscillation power in the neutral behavior condition was significantly lower than that in the moral transgression condition. The post-stimulus β-event-related synchronization (β-ERS) was larger for the moral transgression condition than the neutral behavior condition in response to the least fair offers, and larger for neutral behavior than the moral transgression condition in response to the fairest offers. In summary, β-ERS was influenced by both proposer type and offer type, which revealed different neural responses to the offer from either a morally transgressive or a neutral behavior proposer.
摘要：
The purpose of this study was to examine the antecedents of academic emotions among university students through real-time and multilevel analyses. We explored the link between state self-control and academic emotions, the influence of self-determination on the relationship between them, and the moderating role of trait self-control. The data was collected over seven consecutive days during which university students (N=155) completed smartphone questionnaires. Data was organized into hierarchical two-level structures, where situations (Level 1) nested within individuals (Level 2). The results showed that positive emotions were negatively predicted by state self-control while negative emotions were positively predicted by state self-control. Moreover, state self-control under low self-determination was a significant negative predictor of positive emotions, whereas high self-determination had no predictive effect on positive emotions. The relationship between self-determination and negative emotions was further moderated by trait self-control. The limitations of this study and future research directions are also discussed.
摘要：
The world can be represented by two layers of information: How it appears on the outside (outward appearance) and what it is on the inside (inner state). To what extent an outward appearance is assumed to reflect the inner state is fundamental to social inference and judgments. Conceptualizing inference in terms of the relationship between the outward appearance and the inner state generates an integrative interpretation for a wide range of phenomena. We showed that Chinese were more likely than Euro-Canadians to make inference of inner state that deviated from outward appearance, whereas Euro-Canadians were more likely than Chinese to infer a convergence between outward appearance and inner state (Studies 1-5). We observed these cross-cultural patterns in various contexts involving people or physical structures. Individual differences in correspondence bias or response bias did not explain these patterns. The lay belief that outward appearance can be misleading mediated the cultural effects (Study 4). To probe the underlying process, two additional experiments showed that highlighting the misleading nature of appearance, but not highlighting the power of the situation, reduced Americans' beliefs (Study 6) and inference (Study 7) that the outward appearance reflects the inner state. By focusing on the assumed relationship between the outward appearance and inner state, these findings provide a unique angle for understanding cross-cultural phenomena and have practical implications in daily life. (PsycInfo Database Record (c) 2023 APA, all rights reserved).
期刊：
PHYSICAL CHEMISTRY CHEMICAL PHYSICS,2023年25(41):27967-27980 ISSN：1463-9076
通讯作者：
Zhao, YJ;Gong, Z
作者机构：
[Ning, Shangbo; Zhao, Yunjie; Li, Anbang] Cent China Normal Univ, Dept Phys, Wuhan 430079, Peoples R China.;[Ning, Shangbo; Zhao, Yunjie; Li, Anbang] Cent China Normal Univ, Inst Biophys, Wuhan 430079, Peoples R China.;[Liu, Maili; Gong, Zhou; Sun, Min; Dong, Xu] Chinese Acad Sci, Innovat Acad Precis Measurement Sci & Technol, State Key Lab Magnet Resonance & Atom Mol Phys, Wuhan 430071, Hubei, Peoples R China.;[Zeng, Chen] George Washington Univ, Dept Phys, Washington, DC 20052 USA.
通讯机构：
[Zhao, YJ ; Gong, Z ] C;Cent China Normal Univ, Dept Phys, Wuhan 430079, Peoples R China.;Cent China Normal Univ, Inst Biophys, Wuhan 430079, Peoples R China.;Chinese Acad Sci, Innovat Acad Precis Measurement Sci & Technol, State Key Lab Magnet Resonance & Atom Mol Phys, Wuhan 430071, Hubei, Peoples R China.
摘要：
Designing inhibitors for RNA is still challenging due to the bottleneck of maintaining the binding interaction of inhibitor-RNA accompanied by subtle RNA flexibility. Thus, the current approach usually needs to screen thousands of candidate inhibitors for binding. Here, we propose a dynamic geometry design approach to enrich the hits with only a tiny pool of designed geometrically compatible scaffold candidates. First, our method uses graph-based tree decomposition to explore the complementarity rigid binding cyclic peptide and design the amino acid side chain length and charge to fit the RNA pocket. Then, we perform an energy-based dynamical network algorithm to optimize the inhibitor-RNA hydrogen bonds. Dynamic geometry-guided design yields successful inhibitors with low micromolar binding affinity scaffolds and experimentally competes with the natural RNA chaperone. The results indicate that the dynamic geometry method yields higher efficiency and accuracy than traditional methods. The strategy could be further optimized to design the length and chirality by adopting nonstandard amino acids and facilitating RNA engineering for biological or medical applications. Designing inhibitors for RNA is still challenging due to the bottleneck of maintaining the binding interaction of inhibitor-RNA accompanied by subtle RNA flexibility.
作者机构：
[Zhang, LS; Wang, Shuwen; Feng, Shuo; Zhang, Lishan] Cent China Normal Univ, Fac Artificial Intelligence Educ, Wuhan, Peoples R China.;[Cai, Zhihui] Cent China Normal Univ, Sch Psychol, Wuhan, Peoples R China.
通讯机构：
[Zhang, LS ] C;Cent China Normal Univ, Fac Artificial Intelligence Educ, Wuhan, Peoples R China.
关键词：
Architectures for educational technology;systems;Improving classroom teaching;Human-computer interface;Teaching;learning strategies
摘要：
Researchers have designed a series of classroom orchestration systems (COSs) to support teachers' real-time classroom management of multiple social planes. However, few studies have systematically summarized the implementation of COSs’ general functions (teacher awareness, class instruction, and student coordination) and investigated the effect sizes of COSs on teachers and students. This work identified 67 systems and 22 empirical papers reporting 57 studies with effect sizes to address the research gaps. The qualitative analyses summarized the foci and implementation methods of each general function. The quantitative analyses showed that the overall effects of COSs were medium: g = 0.603 for studies with the no-treatment control, g = 0.536 for studies with the treatment control. No publication bias existed, and the results were robust. Moderator analyses determined two important moderators (teacher awareness and measurement type) of the effects. Overall, the current study revealed the effectiveness of COSs in broad contexts and explained how teacher, machine and student could work together in classroom to some extent.
通讯机构：
[Xin Hao] S;School of Psychology, Central China Normal University, Wuhan, China<&wdkj&>Key Laboratory of Adolescent Cyberpsychology and Behavior (CCNU), Ministry of Education, Wuhan, China
关键词：
Perceived support from family;Perceived support from friends;Resilience;Loneliness;Problematic social media usage
摘要：
Problematic social media use (PSMU) among adolescents has raised global concern in the current digital age. Despite the important role of perceived social support in adolescents’ PSMU has been examined, possible different influences between perceived support from family and friends are still unknown. To address the gap, the present study aimed to examine how perceived support from family and friends is associated differently with PSMU and the mediating roles of resilience and loneliness therein. A sample of 1056 adolescents was recruited to complete standard questionnaires. Mediation analysis showed that resilience and loneliness mediated this association partially between perceived support from family and PSMU but totally between perceived support from friends and PSMU. Further, ANOVA-based analysis showed that influences of perceived support from family and friends on PSMU were mutually independent, and there was no interaction between them. Our results not only highlight different and independent impacts of perceived support from family and friends on PSMU, but also clarify the mediating mechanisms linking perceived social support to adolescent PSMU.
