Efficient synthesis of furo[2,3-d]pyrimidin-4(3H)-ones
作者：
Hu, Yang-Gen;Li, Gui-Hua;Ding, Ming-Wu*
期刊：
ARKIVOC ,2008年2008(13):151-158 ISSN：1551-7004
通讯作者：
Ding, Ming-Wu
作者机构：
[Hu, Yang-Gen; Ding, Ming-Wu] Cent China Normal Univ, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China.;[Hu, Yang-Gen; Li, Gui-Hua] Yunyang Med Coll, Dept Med Chem, Shiyan 442000, Peoples R China.
通讯机构：
[Ding, Ming-Wu] C;Cent China Normal Univ, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China.
关键词：
Aza-Wittig reaction;Furo[2,3-d]pyrimidin-4(3H)-one;Iminophosphorane;Isocyanate
摘要：
The carbodiimides 4, obtained from reactions of iminophosphorane 3 with aromatic isocyanates, reacted with amines or phenols to give 2-substituted furo[2,3-d]pyrimidin-4(3H)-ones 6 in the presence of catalytic amount of sodium alkoxide or solid potassium carbonate in good yields. ©ARKAT USA, Inc.
语种：
英文
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新型含噻吡喃环的唑类衍生物的合成及抑菌活性
作者：
黄年玉;钟莹;王文琴;刘明国;丁明武
作者机构：
华中师范大学教育部农药与化学生物学重点实验室
会议名称：
中国化工学会农药专业委员会第十三届年会
会议时间：
2008-05-12
会议地点：
井冈山
会议论文集名称：
中国化工学会农药专业委员会第十三届年会论文集
关键词：
唑类杀菌剂;羟菌唑;噻毗喃;化学合成;抑菌活性
摘要：
唑类杀菌剂显示出优良的抑菌活性，本文以商品化杀菌剂“羟菌唑”为结构先导，设计并合成新型含噻吡喃环的唑类衍生物，并研究了其抑菌活性。
语种：
中文
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2-胺基（芳氧基）-5，8，9-三甲基噻吩并吡啶并[4，3-d]嘧啶-4（3H）-酮的合成和生物活性
作者：
Liu Jian-Chao* ;He Hong-Wu;Ding Ming-Wu
期刊：
有机化学 ,2008年28(4):632-637 ISSN：0253-2786
通讯作者：
Liu Jian-Chao
作者机构：
[Ding Ming-Wu; Liu Jian-Chao; He Hong-Wu] Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China.;[Liu Jian-Chao] Cent S Univ, Coll Chem & Chem Engn, Changsha 410083, Peoples R China.
通讯机构：
[Liu Jian-Chao] C;Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China.
关键词：
Aza-Wittig法;吡啶并[4;3-d]嘧啶;除草活性;杀菌活性
摘要：
利用串联Aza-Wittig法合成了两类共计16个未见文献报道的噻吩并吡啶并嘧啶类化合物,通过IR,1H NMR,EI-MS,元素分析等方法对所合成的化合物进行了结构表征,化合物II-1还通过了X单晶衍射的进一步确证.并初步测定了所合成化合物的杀虫、杀菌和除草活性.结果表明:所测化合物的杀虫活性较差,但大部分化合物具有一定的除草活性和良好的杀菌活性.
语种：
中文
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4,5-二氢咪唑并[1,2-b]-1′,2′,4′-***-4-酮衍生物的合成与杀菌活性
作者：
Fu, Bo-Qiao;Yuan, Ju-Zhen;Ding, Ming-Wu*
期刊：
有机化学 ,2007年27(10):1268-1272 ISSN：0253-2786
通讯作者：
Ding, Ming-Wu
作者机构：
[Yuan, Ju-Zhen; Fu, Bo-Qiao; Ding, Ming-Wu; Ding, MW] Cent China Normal Univ, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China.
通讯机构：
[Ding, Ming-Wu] C;Cent China Normal Univ, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China.
关键词：
4,5-二氢咪唑并[1,2-b]-1′,2′,4′-***-4-酮;氮杂Wittig反应;碳二亚胺;杀菌活性
摘要：
应用芳基异氰酸酯与烯基膦亚胺1的氮杂Wittig反应,得到的碳二亚胺2,再与水合肼作用得到氨基咪唑啉酮衍生物4.而后用4与芳基异氰酸酯(或酰氯)、三苯基膦、六氯乙烷和三乙胺"一锅"反应,得到4,5-二氢咪唑并[1,2-b]-1′,2′,4′-***-4-酮衍生物6或7.探讨了所合成新型稠杂环化合物的生物活性,结果表明部分化合物表现出良好的杀菌活性.如7c在50 mg/L浓度时,对棉花枯萎菌、稻瘟菌、黄瓜灰霉菌和油菜菌核菌的抑制率均达100%.
语种：
中文
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含***基的噻吩并嘧啶酮衍生物的合成与杀菌活性
作者：
孙勇;刘明国;丁明武
作者机构：
华中师范大学教育部农药与化学生物学重点实验室，武汉，430079
会议名称：
国家农药创制工程技术研究中心2007学术研讨会暨第四届湖南省湖北省农药植保学术交流会
会议时间：
2007-08-15
会议地点：
长沙
关键词：
噻吩并嘧啶酮衍生物;稠杂环化合物;合成工艺;杀菌活性;***基
摘要：
噻吩并嘧啶酮衍生物是一类具有良好生物活性的稠杂环化合物，如一些 2-烷氧基及烷基噻吩并嘧啶酮表现出优良的杀菌活性。另外，***类杀菌剂由于具有杀菌谱广、活性高、可内吸传导、价格合理等优点，一直占据了大量的杀菌剂市场。近年来，新型唑类杀菌剂的研究仍然十分活跃，并开发了一些性能更优良的杀菌剂品种。最近，氮杂 Wittig 反应广泛地应用于氮杂环的合成，该反应原料易得、条件温和、反应选择性好，已成为一种合成氮杂环的有效手段。笔者曾报道应用氮杂 Wittig 反应合成噻吩并嘧啶酮杂环的方法，部分化合物表现出抑菌活性，这里进一步报道应用该法合成含***基的噻吩并嘧啶酮杂环。
语种：
中文
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Improved synthesis of 2-(3H)Benzothiazolethiones under microwave irradiation
作者：
Wei Huang;Ying Tan;Ming‐Wu Ding;Guang‐Fu Yang
（ 期刊：
Synthetic Communications ,2007年37(3):369-376 ISSN：0039-7911
通讯作者：
Yang, Guang-Fu
作者机构：
[Guang‐Fu Yang; Ying Tan; Wei Huang; Yang, GF; Ming‐Wu Ding] Cent China Normal Univ, Coll Chem, Key Lab Pesticide & Chem Biol Minist Educ, Wuhan, Peoples R China.
通讯机构：
[Yang, Guang-Fu] C;Cent China Normal Univ, Coll Chem, Key Lab Pesticide & Chem Biol Minist Educ, Wuhan, Peoples R China.
关键词：
2-mercaptobenzothiazole;microwave irradiation;ortho-haloanline;potassium O-ethyl dithiocarbonate
摘要：
Abstract 2‐(3H)Benzothiazolethiones (2‐mercaptobenzothiazole) are prepared by an improved method, which utilizes microwave‐assisted cyclization of the corresponding ortho‐haloanlines with potassium O‐ethyl dithiocarbonate. By using microwave irradiation, the relative reactivity of 2‐chloroanilines was greatly improved to the same level as that of 2‐fluoroanilines and 2‐bromoanilines.
语种：
英文
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Construction of a combinatorial library of 2-(4-oxo-4H-1-benzopyran-3-yl)-4-thiazolidinones by microwave-assisted one-pot parallel syntheses
作者：
Zhou, Zhong‐Zheng;Huang, Wei;Ji, Feng‐Qin;Ding, Ming‐Wu;Yang, Guang‐Fu
（ 期刊：
Heteroatom Chemistry ,2007年18(4):381-389 ISSN：1042-7163
通讯作者：
Yang, Guang-Fu
作者机构：
[Yang, Guang‐Fu; Huang, Wei; Zhou, Zhong‐Zheng; Ji, Feng‐Qin; Yang, GF; Ding, Ming‐Wu] Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China.
通讯机构：
[Yang, Guang-Fu] C;Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China.
摘要：
A one‐pot liquid‐phase combinatorial synthesis of 2‐(4‐oxo‐4H‐1‐benzopyran‐3‐yl)‐4‐thiazolidinones bearing diverse substituents at the 3‐position under microwave irradiation was successfully performed using 3‐formyl chromone, primary amine, and mercaptoacetic acid as reactants. Compared to an identical library generated by conventional parallel synthesis, the microwave‐assisted parallel synthesis approach dramatically decreased the reaction time from an average of 9 h to 5 min, and substantially increased the product yields. The coupling of microwave technology with liquid‐phase combinatorial synthesis constitutes a novel and particularly attractive avenue for the rapid generation of structurally diverse libraries. © 2007 Wiley Periodicals, Inc. Heteroatom Chem 18:381–389, 2007; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20309
语种：
英文
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2-(1-Naphthylmethyl)-1H-benzo[d]imidazole
作者：
Ding, Ming-Wu* ;Hu, Yang-Gen;Liu, Ming-Guo
期刊：
ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY ,2007年63(7):O3184-U3259 ISSN：2053-2296
通讯作者：
Ding, Ming-Wu
作者机构：
[Ding, Ming-Wu] China Gorges Univ 3, Coll Chem & Life Sci, Hubei Key Lab Native Compounds & Chem Biol, Yichang 443002, Peoples R China.;Cent China Normal Univ, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China.;Yunyang Med Coll, Dept Med Chem, Shiyan 442000, Peoples R China.
通讯机构：
[Ding, Ming-Wu] C;China Gorges Univ 3, Coll Chem & Life Sci, Hubei Key Lab Native Compounds & Chem Biol, Yichang 443002, Peoples R China.
摘要：
In the title compound, C18H14N2, the benzimidazole and naphthalene ring systems are planar, making a dihedral angle of 78.71 (1)° with each other. The packing of the mol-ecules in the crystal structure is mainly due to an inter-molecular N - H⋯N hydrogen bond. © International Union of Crystallography 2007.
语种：
英文
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NEW EFFICIENT SYNTHESIS OF 2-SUBSTITUTED BENZOTHIENO[3,2-d]PYRIMIDIN-4(3H)-ONES VIA AN IMINOPHOSPHORANE
作者：
Sheng-Zhen Xu;Yang-Gen Hu;Ming-Wu Ding
作者机构：
[Sheng-Zhen Xu; Yang-Gen Hu; Ming-Wu Ding] Key Laboratory of Pesticide & Chemical Biology of Ministry of Education,Central China Normal University,Wuhan,430079,P.R.China
会议名称：
第17届国际磷化学学术会议(The 17th International Conference on Phosphorus Chemistry)
会议时间：
2007-4-15
会议地点：
厦门
会议主办单位：
中国化学会
会议论文集名称：
第17届国际磷化学学术会议(The 17th International Conference on Phosphorus Chemistry)论文集
语种：
英文
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Synthesis of a library of imidazolin-4-ones using poly(ethylene glycol) as soluble support
作者：
Li, Hong-Xia;Xie, Chang;Ding, Ming-Wu
* ;Liu, Zu-Ming;Yang, Guang-Fu
（ 期刊：
SYNLETT ,2007年2007(14):2280-2282 ISSN：0936-5214
通讯作者：
Ding, Ming-Wu
作者机构：
[Yang, Guang-Fu; Liu, Zu-Ming; Ding, Ming-Wu; Xie, Chang; Li, Hong-Xia; Ding, MW] Cent China Normal Univ, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China.
通讯机构：
[Ding, Ming-Wu] C;Cent China Normal Univ, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China.
关键词：
poly(ethylene glycol);polymer-supported;aza-Wittig reaction;imidazolin-4-one;ylides
摘要：
A library of imidazolin-4-ones has been synthesized using poly(ethylene glycol) (PEG) as soluble polymer support. The imidazolin-4-ones 6 or 7 were synthesized effectively by reaction of primary amine with PEG-supported carbodiimides 4, which were obtained from aza-Wittig reaction of PEG-supported iminophosphoranes 3 with isocyanates. © Georg Thieme Verlag Stuttgart.
语种：
英文
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Synthesis and structure of 2-substituted thieno[3 ',2 ': 5,6]pyrido[4,3-d]pyrimidin-4(3H)-one derivatives
作者：
Liu, Jian-Chao;He, Hong-Wu* ;Ding, Ming-Wu
期刊：
Helvetica Chimica Acta ,2007年90(5):999-1005 ISSN：0018-019X
通讯作者：
He, Hong-Wu
作者机构：
[He, Hong-Wu; Liu, Jian-Chao; Ding, Ming-Wu] Cent China Normal Univ, Key Lab Pesticide & Chem Biol, Minist Educ, Coll Chem, Wuhan 430079, Peoples R China.
通讯机构：
[He, Hong-Wu] C;Cent China Normal Univ, Key Lab Pesticide & Chem Biol, Minist Educ, Coll Chem, Wuhan 430079, Peoples R China.
关键词：
Pyrido[4,3‐d]pyrimidin‐4(3H)‐one;Aza‐Wittig reaction
摘要：
A series of new 2-substituted 3-(4-chlorophenyl)-5,8,9- trimethylthieno[3′,2′:5,6]pyrido[4,3-d]pyrimidin-4(3H)-ones 8 were synthesized via an aza-Wittig reaction. Phosphoranylideneamino derivatives 6a or 6b reacted with 4-chlorophenyl isocyanate to give carbodiimide derivatives 7a or 7b, respectively, which were further treated with amines or phenols to give compounds 8 in the presence of a catalytic amount of EtONa or K 2CO3. The structure of 2-(4-chlorophenoxy)-3-(4- chlorophenyl)-5,8,9-trimethylthieno[3′,2′:5,6]pyrido[4,3-d] pyrimidin-4(3H)-one (8j) was comfirmed by X-ray analysis. © 2007 Verlag Helvetica Chimica Acta AG.
语种：
英文
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Synthesis and properties of novel imidazolone derivatives containing a sulfur atom
作者：
Huang, Xiaobo* ;Liu, Zhaojie;Yang, Fengling;Ding, Mingwu
期刊：
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS ,2007年182(5):939-950 ISSN：1042-6507
通讯作者：
Huang, Xiaobo
作者机构：
[Huang, Xiaobo] Wenzhou Univ, Dept Chem & Mat Sci, Coll Chem, Wenzhou 325027, Peoples R China.;Cent China Normal Univ, Coll Chem, Wuhan 430070, Peoples R China.;Xuchang Univ, Dept Chem, Coll Chem, Xuchang, Peoples R China.
通讯机构：
[Huang, Xiaobo] W;Wenzhou Univ, Dept Chem & Mat Sci, Coll Chem, Wenzhou 325027, Peoples R China.
关键词：
aza-Wittig reaction;crystal structure;fungicidal activities;herbicidal activities;Imidazolinone derivatives;vinyliminophosphorane
摘要：
Novel 5-(2-chlorophenylmethylidene)-2-thio-4-imidazolinones 3 and 2-Alkythio-5-(2-chlorophenylmethylidene)-4H-imidazolin-4-ones 4 have been synthesized via a tandem aza-Wittig reaction to develop more imidazolinones that may possess biological activities. The target compounds were identified by GC-MS, IR, and 1H NMR spectroscopies, and element analysis, and, in the case of 4k, its structure was established by single crystal X-ray diffraction. They showed not only fungicidal activities against Gibberella zeae, Cercospora beticola, Fusarium oxysporium, Rhizoctonia solani, and Botryosphaeria berengeriana, but also growth inhibition of Barnyard grass and Cole root and stalk.
语种：
英文
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2-lsopropylamino-1-phenyl-1H-imidazol-5(4H)-one
作者：
Li, Hong-Xia;Gao, Hai-Tao;Ding, Ming-Wu* ;Zeng, Xiao-Hua
期刊：
ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY ,2006年62(12):o5704-o5706 ISSN：2053-2296
通讯作者：
Ding, Ming-Wu
作者机构：
[Ding, Ming-Wu] Cent China Normal Univ, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China.;Yunyang Med Coll, Dept Med Chem, Shiyan 442000, Peoples R China.
通讯机构：
[Ding, Ming-Wu] C;Cent China Normal Univ, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China.
摘要：
The title compound, C12H15N3O, crystallizes with four independent molecules in the asymmetric unit. The five-membered heterocyclic rings are essentially planar. The crystal packing is stabilized by intra- and intermolecular hydrogen bonds and π-π stacking interactions. © 2006 International Union of Crystallography All rights reserved.
语种：
英文
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New facile synthesis of 3,5-dihydro-6H-imidazo[1,2-b]-1,2,4-triazol-6-ones by an iminophosphorane-mediated annulation
作者：
Yuan, Ju-Zhen* ;Fu, Bo-Qiao;Ding, Ming-Wu;Yang, Guang-Fu
期刊：
ChemInform ,2006年2006(18):4170-4176 ISSN：1099-0690
通讯作者：
Yuan, Ju-Zhen
作者机构：
[Yuan, Ju-Zhen; Fu, Bo-Qiao; Yang, Guang-Fu; Ding, Ming-Wu] Cent China Normal Univ, Key Lab Pesticide & Chem Biol, Minist Educ, Coll Chem, Wuhan 430079, Peoples R China.
通讯机构：
[Yuan, Ju-Zhen] C;Cent China Normal Univ, Key Lab Pesticide & Chem Biol, Minist Educ, Coll Chem, Wuhan 430079, Peoples R China.
关键词：
3,5-Dihydro-6H-imidazo[1,2-b]-1,2,4-triazol-6-one;Abnormal aza-Wittig reaction;Annulation;Carbodiimide;Iminophosphorane;Synthetic methods
摘要：
Iminophosphorane 1 reacted with an aromatic isocyanate to unexpectedly give a mixture of carbodiimides 2, 3 and 4 through both the normal and the abnormal aza-Wittig reactions. 3-Aminoimidazolone 10 was obtained from the reaction of hydrazine hydrate with carbodiimide 2. Reaction of 10 with triphenyphosphane, hexachloroethane and triethylamine produced iminophosphorane 11 in good yield. A tandem aza-Wittig reaction of iminophosphorane 11 with isocyanate or CS2 generated 3,5-dihydro-6H-imidazo[1,2-b]-1,2,4-triazol-6-ones 13 or 15 in satisfactory yield. Carbodiimides 18, obtained from normal aza-Wittig reactions of vinyl iminophosphorane 17 with aromatic isocyanates, reacted with hydrazine to give 2-arylamino-3-amino-4H-imidazol-4-ones 20. One-pot reactions of 2-arylamino-3-amino-4H-imidazol-4-ones 20 with isocyanates (or acyl chlorides), triphenyphosphane, hexachloroethane and triethylamine produced 3,5-dihydro-6H-imidazo[1,2-b]-1,2,4- triazol-6-ones 22 (or 23) in good yields. ((c) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006).
语种：
英文
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Iminophosphorane-mediated efficient synthesis of new tricyclic 3,5-dihydro-1,2,3-triazolo[4,5-d]-1,2,4-triazolo[1,5-a]pyrimidin-9-ones
作者：
Zhao, JF;Xie, C;Xu, SZ;Ding, MW* ;Xiao, WJ
期刊：
Organic & Biomolecular Chemistry ,2006年4(1):130-134 ISSN：1477-0520
通讯作者：
Ding, MW
作者机构：
[Zhao, JF; Xu, SZ; Xiao, WJ; Xie, C; Ding, MW] Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China.
通讯机构：
[Ding, MW] C;Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China.
摘要：
The carbodiimides 2, obtained from aza-Wittig reactions of iminophosphorane 1 with aromatic isocyanates, reacted with hydrazine to give selectively 6-amino-7H-1,2,3-triazolo[4,5-d]pyrimidin-7-ones 5. Compounds 5 were further transformed to iminophosphoranes 6 by reaction with triphenylphosphine, hexachloroethane and triethylamine. A tandem aza-Wittig reaction of iminophosphorane 6 with isocyanate or acyl chloride generated previously unreported 3,5-dihydro-1,2,3-triazolo[4,5-d]-1,2,4-triazolo[1,5-a]pyrimidin-9- ones 10 or 12 in satisfactory yield. X-ray structure analysis of 10g verified the proposed structure and the reaction selectivity. ©The Royal Society of Chemistry 2006.
语种：
英文
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A facile synthesis of 2-substituted thieno[3 ',2 '-5,6]-pyrido[4,3-d]pyrimidin-4(3H)-ones
作者：
Liu, Jian-Chao;He, Hong-Wu* ;Ren, Qing-Yun;Ding, Ming-Wu
期刊：
Journal of Heterocyclic Chemistry ,2006年43(3):803-806 ISSN：0022-152X
通讯作者：
He, Hong-Wu
作者机构：
[He, Hong-Wu; Ren, Qing-Yun; Liu, Jian-Chao; Ding, Ming-Wu] Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China.
通讯机构：
[He, Hong-Wu] C;Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China.
摘要：
The thienopyridine derivative 2, obtained from reaction of acetoacetic ester with 1 in the presence of tin tetrachloride, was treated with triphenylphosphine in hexachloroethane and Et3N to give iminophosphorane 3. Iminophosphorane 3 reacted with phenyl isocyanate to give carbodiimide 4, which was further treated with phenols or ethenol to produce 2-substituted 5,8,9-trimethyl-3-phenyl-thieno[3′,2′-5,6]pyrido[4,3- d]pyrimidin-4(3H)-ones 5 in presence of catalytic amount of K2CO 3 or EtONa. The structures of compounds 5 were confirmed by 1H NMR, IR, MS, and elemental analysis.
语种：
英文
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4-Benzylidene-1-phenyl-2-propylamino-1H-imidazol-5(4H)-one
作者：
Yuan, JZ;Ding, MW*
期刊：
ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY ,2006年62(2):o647-o648 ISSN：2053-2296
通讯作者：
Ding, MW
作者机构：
[Yuan, JZ; Ding, MW] Cent China Normal Univ, Key Lab Pesticides & Chem Biol, Minist Educ, Coll Chem, Wuhan 430079, Peoples R China.
通讯机构：
[Ding, MW] C;Cent China Normal Univ, Key Lab Pesticides & Chem Biol, Minist Educ, Coll Chem, Wuhan 430079, Peoples R China.
摘要：
In the title compound, C19H19N3O, the five-membered imidazolone ring is essentially planar. Intermolecular N - H⋯O hydrogen bonds form an infinite chain. The C - N and C - C bond lengths indicate electron delocalization. © 2006 International Union of Crystallography All rights reserved.
语种：
英文
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Facile synthesis of 2-alkylthio-5,5-dimethyl-4H-imidazol-4-ones
作者：
Yuan, Ju-Zhen;Wei, Jia-Jia;Ding, Ming-Wu*
期刊：
Synthetic Communications ,2006年36(19):2921-2925 ISSN：0039-7911
通讯作者：
Ding, Ming-Wu
作者机构：
[Yuan, Ju-Zhen; Ding, Ming-Wu; Wei, Jia-Jia; Ding, MW] Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China.
通讯机构：
[Ding, Ming-Wu] C;Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China.
关键词：
Aza-Wittig reaction;4H-imidazol-4-one;isothiocyanate;synthesis;EFFICIENT SYNTHESIS;DERIVATIVES
摘要：
The isothiocyanate 3, obtained from aza-Wittig reaction of iminophosphorane 2 with CS2, reacts with phenylhydrazine to give thiosemicarbazide 4. Reactions of 4 with alkyl halides in the presence of K2CO3 directly provided 2-alkylthio-4H-imidazol-4- ones 6 in good yields.
语种：
英文
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具有杀菌活性的咪唑并[2,1-b][1,2,4]***的合成
作者：
袁菊珍;丁明武;杨光富
作者机构：
[袁菊珍; 丁明武; 杨光富] 华中师范大学化学学院教育部农药与化学生物学重点实验室
会议名称：
第七届全国磷化学化工暨第四届海峡化学生物学、生物技术与医药发展讨论会
会议时间：
2006-04
会议地点：
中国河南郑州
摘要：
<正>咪唑啉类杂环化合物具有多种生物活性,如除草、杀菌、抗肿瘤。尤其是一些2-烷硫基咪唑啉酮表现出显著的杀菌活性,如罗纳普朗克公司开发的新杀菌剂RPA407213,就是2-甲硫基咪唑啉酮衍生物。由于咪唑啉酮杂环具有优良的生物活性,应用新的合成方法及生物活性的研究一直十分活跃。我们曾应用氮杂Wittig反应合成具有杀菌活性的咪唑啉酮衍生物(Ⅰ)和(Ⅱ)．
语种：
中文
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2-Ethoxy-3-phenyl-1-benzothieno[3,2-d]pyrimidin-4(3H)-one
作者：
Xu, Sheng-Zhen;Hu, Yang-Gen;Wang, Xiang;Ding, Ming-Wu*
期刊：
ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY ,2006年62(6):o2229-o2230 ISSN：2053-2296
通讯作者：
Ding, Ming-Wu
作者机构：
[Wang, Xiang; Xu, Sheng-Zhen; Ding, Ming-Wu; Hu, Yang-Gen; Ding, MW] Cent China Normal Univ, Coll Chem, Key Lab Pesticides & Chem Biol, Minist Educ, Wuhan 430079, Peoples R China.
通讯机构：
[Ding, Ming-Wu] C;Cent China Normal Univ, Coll Chem, Key Lab Pesticides & Chem Biol, Minist Educ, Wuhan 430079, Peoples R China.
摘要：
In the crystal structure of the title compound, C18H 14N2O2S, the packing of the molecules is mainly governed by intermolecular π-π interactions. © 2006 International Union of Crystallography. All rights reserved.
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英文
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