作者机构：
[Zhang, Man; Zhang, Jiawei; Zhang, M] Cent China Normal Univ, Sch Foreign Languages, Wuhan, Peoples R China.;[Zhang, Man; Zhang, M] Humboldt Univ, Fac Language Literature & Humanities, Berlin, Germany.
通讯机构：
[Zhang, M ] C;Cent China Normal Univ, Sch Foreign Languages, Wuhan, Peoples R China.;Humboldt Univ, Fac Language Literature & Humanities, Berlin, Germany.
作者：
Gong, Xin;Yu, Shufan;Xu, Jie;Qiao, Ailing;Han, Han
期刊：
Education and Information Technologies,2024年29(5):6383-6405 ISSN：1360-2357
通讯作者：
Qiao, AL;Yu, SF
作者机构：
[Gong, Xin; Qiao, Ailing] Capital Normal Univ, Coll Educ, 105 West Third Ring North Rd, Beijing 100048, Peoples R China.;[Yu, Shufan] Cent China Normal Univ, Fac Artificial Intelligence Educ, Sch Educ Informat Technol, Wuhan 430079, Hubei, Peoples R China.;[Xu, Jie] Zhejiang Univ, Coll Educ, 866 Yuhangtang Rd,Zijingang Campus, Hangzhou 310058, Peoples R China.;[Han, Han] Beijing Normal Univ, Fac Educ, 19 Xinjiekou Outer St, Beijing 100875, Peoples R China.;[Yu, Shufan] Cent China Normal Univ, Fac Artificial Intelligence Educ, Sch Educ Informat Technol, Wuhan 430079, Hubei, Peoples R China.
通讯机构：
[Yu, SF ; Qiao, AL ] ;Capital Normal Univ, Coll Educ, 105 West Third Ring North Rd, Beijing 100048, Peoples R China.;Cent China Normal Univ, Fac Artificial Intelligence Educ, Sch Educ Informat Technol, Wuhan 430079, Hubei, Peoples R China.
作者机构：
[Li, Guang; Xu, Weiwei; Hameed, Muhammad Salman; Yang, Qinglin; Li, Haibing; Qu, Haonan] Cent China Normal Univ, Coll Chem, Natl Key Lab Green Pesticide, Wuhan 430079, Peoples R China.;[Quan, Jiaxin; Quan, JX] Hanjiang Normal Univ, Dept Chem Biol & Environm Engn, Shiyan 442000, Peoples R China.;[Zhang, J; Zhang, Jin] Yunnan Normal Univ, Coll Chem & Chem Engn, Kunming 650092, Peoples R China.;[Sun, Zhongyue] Hubei Univ Chinese Med, Sch Lab Med, Wuhan 430065, Peoples R China.
通讯机构：
[Quan, JX ; Sun, ZY ] H;[Li, HB ] C;[Zhang, J ] Y;Cent China Normal Univ, Coll Chem, Natl Key Lab Green Pesticide, Wuhan 430079, Peoples R China.;Hanjiang Normal Univ, Dept Chem Biol & Environm Engn, Shiyan 442000, Peoples R China.
关键词：
arginine;biomimetic;mimic Cyt C transport;nanochannel;pH
摘要：
Proteins are vital components in cells, biological tissues, and organs, playing a pivotal role in growth and developmental processes in living organisms. Cytochrome C (Cyt C) is a class of heme proteins found in almost all life and is involved in cellular energy metabolic processes such as respiration, mainly as electron carriers or terminal reductases. It binds cardiolipin in the inner mitochondrial membrane, leading to apoptosis. It is a challenge to design a simple and effective artificial system to mimic the complex Cyt C biological transport process. In this paper, an asymmetric biomimetic pH-driven protein gate is described by introducing arginine (Arg) at one end of an hourglass-shaped nanochannel. The nanochannel shows a sensitive protonation-driven protein gate that can be "off" at pH = 7 and "on" at pH = 2. Further studies show that differences in the binding of Arg and Cyt C at different levels of protonation lead to different switching behaviors within the nanochannels, which in turn lead to different surface charges within the nanochannels. It can be used for detecting Cyt C and as an excellent and robust gate for developing integrated circuits and nanoelectronic logic devices.
期刊：
Archives of Sexual Behavior,2024年53(1):247-261 ISSN：0004-0002
通讯作者：
He, XY
作者机构：
[He, Xianyou; Zhang, Siyue; He, Chunyan; Liang, Fuqun; He, XY; Wu, Hairu] South China Normal Univ, Key Lab Brain Cognit & Educ Sci, Minist Educ, Guangzhou, Peoples R China.;[He, Xianyou; Zhang, Siyue; He, Chunyan; Liang, Fuqun; He, XY; Wu, Hairu] South China Normal Univ, Guangdong Key Lab Mental Hlth & Cognit Sci, Guangzhou, Peoples R China.;[He, Xianyou; Zhang, Siyue; He, Chunyan; Liang, Fuqun; He, XY; Wu, Hairu] South China Normal Univ, Ctr Studies Psychol Applicat, Guangzhou, Peoples R China.;[He, Xianyou; Zhang, Siyue; He, Chunyan; Liang, Fuqun; He, XY; Wu, Hairu] South China Normal Univ, Sch Psychol, Zhongshan Ave West 55, Guangzhou 510631, Peoples R China.;[Lei, Yatian] Cent China Normal Univ, Sch Psychol, Wuhan, Peoples R China.
通讯机构：
[He, XY ] S;South China Normal Univ, Key Lab Brain Cognit & Educ Sci, Minist Educ, Guangzhou, Peoples R China.;South China Normal Univ, Guangdong Key Lab Mental Hlth & Cognit Sci, Guangzhou, Peoples R China.;South China Normal Univ, Ctr Studies Psychol Applicat, Guangzhou, Peoples R China.;South China Normal Univ, Sch Psychol, Zhongshan Ave West 55, Guangzhou 510631, Peoples R China.
摘要：
Contemporary women frequently employ beautification strategies. The impact of such strategies, such as plastic surgery, on mating popularity in different mate contexts remains unclear. To investigate this issue, the current study conducted two experiments. In Experiment 1, beautification strategies were manipulated using three images of the same female with different conditions (natural, makeup, and plastic surgery). The results indicated that when the beautification strategies were not informed, surgical-enhanced and makeup targets were perceived as significantly more attractive, loyal, and popular among potential mates than natural targets. However, when participants were informed of the beautification strategies, both natural and makeup targets showed a significant increase in perceived loyalty and mating popularity. In contrast, surgically enhanced targets saw a reduction in these dimensions. Experiment 2 aimed to reduce the confounding effect of facial attractiveness by using vignettes. The results indicated that the mating popularity of natural targets was significantly higher than that of makeup or surgically enhanced targets, with surgically enhanced targets being the least popular. Moreover, the results revealed the mediating role of perceived loyalty in the impact of beautification strategies on long-term mating popularity. This study sheds light on the potential stigmatization and negative bias toward beautification strategies in the mating market. Additionally, it provides guidance for women who intend to enhance their mate popularity through plastic surgery.
关键词：
Compressible Navier-Stokes-Allen-Cahn system;Strong/classical solutions;Density-dependent viscosity;Large initial data
摘要：
This paper is concerned with a one-dimensional isentropic compressible Navier-Stokes-Allen-Cahn system with density-dependent viscosity, which models the motion of a mixture of two viscous compressible fluids. The case when the pressure $ p(\rho) = \rho^\gamma $, the viscosity $ \nu(\rho, \chi) = \rho^\alpha $, the interface thickness $ \delta(\rho) = \rho^\beta $ and the relaxation time function $ a(\rho, \chi, \chi_y) = \rho^\lambda $ is considered, where $ \rho $ and $ \chi $ are the density and the phase variable, respectively, and $ \gamma, \alpha, \beta, \lambda\in\mathbb{R} $ are parameters. Under some suitable assumptions on the parameters $ \gamma , \alpha, \beta, \lambda $ and the initial data, we prove the global existence and large-time behavior of nonvacuum strong and classical solutions to its Cauchy problem with large initial data. This appears to be the first global existence result on the Cauchy problem of the compressible Navier-Stokes-Allen-Cahn system with density-dependent viscosity and large data.
作者机构：
[Manso, F; Bastid, N; Acharya, S; Tang, S; Lopez, X; Barret, V; Porteboeuf-Houssais, S; Dupieux, P; Crochet, P] Université Clermont Auvergne, CNRS/IN2P3, LPC, Clermont-Ferrand, France;[Grecka, E; Isakov, A; Adamová, D; Kushpil, S; Bielčíková, J; Krizek, F; Kotliarov, A] Nuclear Physics Institute of the Czech Academy of Sciences, Husinec-Řež, Czech Republic;[Kebschull, U; Janson, T; Adler, A] Johann-Wolfgang-Goethe Universität Frankfurt Institut für Informatik, Fachbereich Informatik und Mathematik, Frankfurt, Germany;[Wenzel, S C; Fuchs, U; Kundu, S; Zardoshti, N; Kalweit, A; Kluge, A; Shahoyan, R; Kučera, V; Larionov, P; Chochula, P; Schmidt, M O; Pinazza, O; Hillemanns, H; Riegler, W; Alkin, A; Jowett, J M; Schukraft, J; Lamanna, M; Chibante Barroso, V; Wegrzynek, A; Vande Vyvre, P; Innocenti, G M; Bond, P M; Reidt, F; Keil, M; Konopka, P J; Aglieri Rinella, G; Mazzilli, M; Ferrer, M B; Lautner, L; Morsch, A; Rohr, D; Trogolo, S; Mager, M; Parkkila, J E; Divià, R; Martinengo, P; von Haller, B; Klein, J; Grosa, F; Sanna, I; Costa, F; Tauro, A; Hristov, P; Musa, L; Telesca, A; Grosse-Oetringhaus, J F; Mrnjavac, T; Chapeland, S; Di Mauro, A; Carballo, A A; Barth, K; Colocci, M; Carnesecchi, F; Gargiulo, C; Laudi, E; Suljic, M; Eulisse, G; Mazuecos, A L; Zampolli, C; Jacazio, N; Augustinus, A; Volkel, B; Puccio, M; Betev, L; Kabus, M J; Grigoras, C; Junique, A] European Organization for Nuclear Research (CERN), Geneva, Switzerland;[Ciacco, M; Agnello, M; Balbino, A; Catalano, F; Fecchio, P; Politano, S; Bufalino, S] Dipartimento DISAT del Politecnico and Sezione INFN, Turin, Italy
摘要：
The production of the ψ(2S) charmonium state was measured with ALICE in Pb-Pb collisions at sqrt[s_{NN}]=5.02 TeV, in the dimuon decay channel. A significant signal was observed for the first time at LHC energies down to zero transverse momentum, at forward rapidity (2.5<y<4). The measurement of the ratio of the inclusive production cross sections of the ψ(2S) and J/ψ resonances is reported as a function of the centrality of the collisions and of transverse momentum, in the region p_{T}<12 GeV/c. The results are compared with the corresponding measurements in pp collisions, by forming the double ratio [σ^{ψ(2S)}/σ^{J/ψ}]_{Pb-Pb}/[σ^{ψ(2S)}/σ^{J/ψ}]_{pp}. It is found that in Pb-Pb collisions the ψ(2S) is suppressed by a factor of ∼2 with respect to the J/ψ. The ψ(2S) nuclear modification factor R_{AA} was also obtained as a function of both centrality and p_{T}. The results show that the ψ(2S) resonance yield is strongly suppressed in Pb-Pb collisions, by a factor of up to ∼3 with respect to pp. Comparisons of cross section ratios with previous Super Proton Synchrotron findings by the NA50 experiment and of R_{AA} with higher-p_{T} results at LHC energy are also reported. These results and the corresponding comparisons with calculations of transport and statistical models address questions on the presence and properties of charmonium states in the quark-gluon plasma formed in nuclear collisions at the LHC.
期刊：
Journal of Carbohydrate Chemistry,2024年 ISSN：0732-8303
通讯作者：
Guo, J
作者机构：
[Zhang, Ru-Yan; Liu, Yan-Ling; Ding, Dong; Guo, J; Wen, Yu; Guo, Jun; Zhou, Shi-Hao; Zou, Yong-Ke] Cent China Normal Univ, Coll Chem, Int Joint Res Ctr Intelligent Biosensing Technol &, Natl Key Lab Green Pesticide, Wuhan 430079, Peoples R China.
通讯机构：
[Guo, J ] C;Cent China Normal Univ, Coll Chem, Int Joint Res Ctr Intelligent Biosensing Technol &, Natl Key Lab Green Pesticide, Wuhan 430079, Peoples R China.
关键词：
Cancer vaccine;c-GAMP;MUC1;MUC1 glycopeptide;poly(I:C);ternary adjuvant system
摘要：
The highly glycosylated mucin 1 (MUC1) serves as a promising target for cancer vaccines. However, the weak immunogenicity of MUC1 greatly impedes its application. Here, we covalently linked a MUC1 glycopeptide to carrier protein bovine serum albumin (BSA), and the resulting BSA-MUC1 conjugate was integrated with a ternary adjuvant system comprising TLR3 agonist poly(I:C), STING agonist c-GAMP, and Alum adjuvant. Compared to adjuvant-free and Alum-adjuvanted groups, the ternary adjuvant group induced 18.3- and 10.9-fold increases in MUC1-specific IgG titers, and effectively suppressed tumor growth. These findings may propose a straightforward yet highly effective strategy for designing vaccines, offering promising prospects in cancer treatment.
期刊：
Educational Research Review,2024年43:100591 ISSN：1747-938X
通讯作者：
Chai, HY
作者机构：
[Chai, Huanyou; Hu, Tianhui] Cent China Normal Univ, Fac Artificial Intelligence Educ, Wuhan 430079, Hubei, Peoples R China.;[Chai, Huanyou] Beijing Normal Univ, Res Ctr Distance Educ, Beijing, Peoples R China.;[Wu, Li] Cent China Normal Univ, Sch Educ, Wuhan 430079, Hubei, Peoples R China.
通讯机构：
[Chai, HY ] C;Cent China Normal Univ, Fac Artificial Intelligence Educ, Wuhan 430079, Hubei, Peoples R China.
关键词：
Computer-based assessment;Collaborative problem solving skills;21st century skills;Theoretical model;Evaluation methodologies
摘要：
Given the widespread concern on collaborative problem solving (CPS) skills, there has been an increasing interest in the last few years to explore how to assess them with digital technologies. This study systematically reviewed how CPS skills have been assessed with digital technologies in the literature. A total of 40 articles were reviewed to analyze specific computer-based assessment instruments of CPS skills from four perspectives: research context, theoretical model for assessment, assessment type, and reliability and validity evidence. The results indicate that most tests target a sample of less than 500 junior students. Nine theoretical models are employed for assessing CPS skills, most of which treat these skills as an explicit combination of social and cognitive skills and are applied to a limited range of participants' age levels, collaboration features, and team compositions. A total of 22 tests have been employed and fallen into four types, i. e., the ones with specific predefined messages in human-agent mode, and those with online chat box, videoconferencing, and face-to-face collaboration in human-human mode. Each type of these tests demonstrates great diversities in participants' age levels, types of CPS task(s), team compositions, types of assessment data, and methods of data recording and scoring. A certain number of tests lack reliability and validity evidence. Our findings are expected to benefit relevant researchers and test developers in terms of providing suggestions for future research which include testing the applicability of theoretical models for assessing CPS skills across a wide range of assessment contexts. In addition, future researchers should improve the development, data processing, and report of those four types of computer-based assessment instruments of CPS skills through different approaches, respectively.
作者机构：
[Wang, Yizhou; Wang, YZ; Chen, Xiaoxiao; Lu, Xinyuan] Cent China Normal Univ, Sch Informat Management, Wuhan 430079, Peoples R China.;[Lu, Xinyuan] Hubei Elect Commerce Res Ctr, Wuhan 430079, Peoples R China.;[Lu, Quan] Hubei Univ Technol, Sch Econ & Management, Wuhan 430068, Peoples R China.
通讯机构：
[Wang, YZ ] C;Cent China Normal Univ, Sch Informat Management, Wuhan 430079, Peoples R China.
关键词：
PLS-SEM;cognitive–affective personality systems theory;conservation of resources theory;cyberloafing;role stress
摘要：
This investigation delves into the pervasive yet insufficiently examined phenomenon of "cyberloafing", characterized by employees engaging in non-work-related internet activities during office hours. Despite its frequent occurrence in contemporary work environments, the fundamental mechanisms underpinning cyberloafing remain largely uncharted. This study uses the conservation of resources theory and the cognitive-affective personality system framework to demystify the relationship between role stress and cyberloafing. We developed a dual-path model to assess the mediating roles of perceived insider status and emotional exhaustion. Employing SPSS and Smart PLS for data analysis, our research sampled 210 corporate employees. The findings reveal that role stress predicts perceived insider status and emotional exhaustion significantly. Notably, while perceived insider status negatively correlates with cyberloafing, emotional exhaustion shows a positive correlation. These factors mediate the relationship between role stress and cyberloafing, underscoring a multifaceted dynamic. Our results provide new theoretical insights into the mechanisms of employee counterproductive behavior, specifically in the context of cyberloafing, and broaden our understanding of its determinants. This study illuminates theoretical nuances and offers practical implications for managerial strategies and future scholarly inquiries into organizational behavior.
摘要：
The intervention of nectar robbers in plant pollination systems will cause some pollinators to modify their foraging behavior to act as secondary robbers, consequently adopting a mixed foraging strategy. The influence of nectar robbing on pollinator behavior may be affected by spatio-temporal difference of robbing intensity, and consequently, may have different effects on the pollination of host plants. However, whether and how the nectar robbing might influence pollinators under different robbing intensity still needs further investigation. In this study, Symphytum officinale was used to detect the effect of nectar robbers on pollinators under different robbing intensity as well as their effects on plant reproductive success. Six robbing levels and three bumblebees with mixed foraging behaviors were used to evaluate the effect of different robbing intensity on pollinator behavior, visitation rate, flower longevity and pollen deposition. Our results indicated that the robbing rate increased gradually with the proportion of robbed flowers, but which did not affect the frequency of legitimate visits. The increase of robbing rate promoted the corolla abscission, and then enhanced the self-pollen deposition, but which had no significant effect on cross-pollen deposition. These results indicate that the overall fitness of S. officinale was improved by combined self and cross-pollination modes when visited by both pollinators and nectar robbers simultaneously. Although nectar robbing is not uncommon, its consequences for pollination in the interaction web have not been well studied. Our results emphasize the significance of indirect impacts in mediating the adaptive outcomes of species interactions.
