作者机构:
[Fu, Zhenrong; Zhou, Zongkui] Minist Educ, Key Lab Adolescent Cyberpsychol & Behav CCNU, Wuhan, Peoples R China.;[Fu, Zhenrong; Zhou, Zongkui] Cent China Normal Univ, Sch Psychol, Key Lab Human Dev & Mental Hlth Hubei Prov, Wuhan, Peoples R China.;[Zhao, Mingyan] Tangshan Gongren Hosp, Dept Psychol, Tangshan, Peoples R China.;[Li, Yuxia] Tangshan Cent Hosp, Dept Neurol, Tangshan, Peoples R China.;[Han, Ying; Li, Yuxia] Capital Med Univ, Dept Neurol, Xuanwu Hosp, Beijing, Peoples R China.
通讯机构:
[Han, Y ] C;[Li, SY ] B;Beijing Normal Univ, State Key Lab Cognit Neurosci & Learning, Haikou 570228, Peoples R China.;Capital Med Univ, Dept Neurol, Xuanwu Hosp, Beijing 100053, Peoples R China.
摘要:
We empirically derived subgroups from the SILCODE SCD cohort using cluster analysis based on eight neuropsychological measures and examined patterns of structural and functional indices of each cluster‐derived subgroup relative to NC. Four SCD subgroups emerged: dysexecutive/mixed, neuropsychiatric, amnestic, and a cluster‐derived normal group. Abstract Aims We evaluated whether Subjective Cognitive Decline (SCD) subtypes could be empirically derived within the Sino Longitudinal Study on Cognitive Decline (SILCODE) SCD cohort and examined associated neuroimaging markers, biomarkers, and clinical outcomes. Methods A cluster analysis was performed on eight neuropsychological test scores from 124 SCD SILCODE participants and 57 normal control (NC) subjects. Structural and functional neuroimaging indices were used to evaluate the SCD subgroups. Results Four subtypes emerged: (1) dysexecutive/mixed SCD (n = 23), (2) neuropsychiatric SCD (n = 24), (3) amnestic SCD (n = 22), and (4) cluster‐derived normal (n = 55) who exhibited normal performance in neuropsychological tests. Compared with the NC group, each subgroup showed distinct patterns in gray matter (GM) volume and the amplitude of low‐frequency fluctuations (ALFF). Lower fractional anisotropy (FA) values were only found in the neuropsychiatric SCD group relative to NC. Conclusion The identification of empirically derived SCD subtypes demonstrates the presence of heterogeneity in SCD neuropsychological profiles. The cluster‐derived normal group may represent the majority of SCD individuals who do not show progressive cognitive decline; the dysexecutive/mixed SCD and amnestic SCD might represent high‐risk groups with progressing cognitive decline; and finally, the neuropsychiatric SCD may represent a new topic in SCD research.
期刊:
Journal of Interpersonal Violence,2023年38(13-14):7911-7940 ISSN:0886-2605
通讯作者:
Yu, Quanlei;Zhang, Lin;Xiong, Qing
作者机构:
[Zheng, Xintong; Chen, Jianwen] Huazhong Univ Sci & Technol, Wuhan, Peoples R China.;[Li, Congcong; Yu, Quanlei] Cent China Normal Univ, Wuhan, Peoples R China.;[Yu, Quanlei] East China Normal Univ, Shanghai, Peoples R China.;[Yu, Quanlei] Minist Educ, Key Lab Adolescent Cyberpsychol & Behav CCNU, Wuhan, Peoples R China.;[Xiong, Qing] Jiangxi Univ Finance & Econ, Nanchang, Peoples R China.
通讯机构:
[Yu, Quanlei] C;[Zhang, Lin] S;[Xiong, Qing] J;Cent China Normal Univ, Sch Psychol, 152 Luoyu Rd, Wuhan 430079, Hubei, Peoples R China.;Shandong Univ Tradit Chinese Med, Changqing Univ Sci & Technol Pk, Sch Hlth, Jinan 250355, Shandong, Peoples R China.
关键词:
peer victimization;problematic Internet use;depression;humor;general strain theory
摘要:
With the increasing development of science and technology, the Internet has become an essential part of people's daily lives providing great convenience. However, the Internet also leads to problematic Internet use (PIU) among adolescents, which has attracted increasing attention from the academic community. Peer victimization is a pervasive stressor among adolescents and has been proven to lead to a series of mental health challenges. Although the association between peer victimization and PIU has been well documented, the underlying mechanism remains unclear. This study aimed to understand how and when peer victimization increases the risk of PIU among adolescents. Building on Agnew's general strain theory, this study hypothesized that depression mediates the relationship between peer victimization and PIU and humor moderates the mediating model. To examine these hypotheses, 469 middle school students were recruited to complete a series of questionnaires on peer victimization, depression, humor, and PIU. The results showed that depression partially mediated the relationship between peer victimization and PIU. A moderated mediation analysis indicated that humor moderated the indirect pathway, consistent with the reverse stress-buffering model, the relationship between peer victimization and depression was stronger for adolescents with high humor. However, the relationship between depression and PIU was weaker in adolescents with high humor, which is in line with the stress-buffering model. These findings could be of significance in understanding the underlying mechanism of PIU associated with peer victimization and provide a new perspective for preventing PIU among adolescents, especially those experiencing peer victimization. The limitations and considerations for future research are discussed.
摘要:
The current methods for measuring patient-reported outcomes for amphetamine (speed) craving have limitation ability to adapt to the needs of individual patients while maintaining consistency in their scores. This study aimed to investigate whether the 40-item Desires for Speed Questionnaire (DSQ) could be improved for assessing clinical subjects using computerized adaptive testing (CAT). A sample of 677 participants from four drug addiction treatment centers in China was utilized in the study. Two types of analysis were conducted using the response data. First, the psychometric properties of all items were evaluated to meet the requirements of CAT. Second, multiple CAT simulations were carried out using real response data. The results indicated that the CAT method, which only required a small number of items (50%-75%), produced results that were only slightly different from the full DSQ assessment in terms of measuring amphetamine craving and criterion validity. In conclusion, this study suggests that developing a DSQ CAT for clinical subjects is useful as it leads to more efficient measurement without compromising the reliability of the test outcomes. (PsycInfo Database Record (c) 2023 APA, all rights reserved).
通讯作者:
Hongyu Ma<&wdkj&>Hongyu Ma Hongyu Ma Hongyu Ma
作者机构:
[Su, Jingxuan; Ma, Hongyu; Shi, Yanwei] Cent China Normal Univ, Sch Psychol, Wuhan, Peoples R China.;[Su, Jingxuan; Ma, Hongyu; Shi, Yanwei] Minist Educ, Key Lab Adolescent Cyberpsychol & Behav CCNU, Wuhan, Peoples R China.;[Shi, Yanwei] Shanghai Normal Univ, Dept Human Resource Management, Shanghai, Peoples R China.;[Zhang, Nan] Beijing Normal Univ, Fac Psychol, Natl Demonstrat Ctr Expt Psychol Educ, Beijing Key Lab Appl Expt Psychol, Beijing, Peoples R China.;[Ma, Hongyu] Cent China Normal Univ, Sch Psychol, Wuhan 430079, Peoples R China.
通讯机构:
[Hongyu Ma; Hongyu Ma Hongyu Ma Hongyu Ma] S;School of Psychology, Central China Normal University;Key Laboratory of Adolescent Cyberpsychology and Behavior (CCNU), Ministry of Education, Wuhan, China
关键词:
conservation of resources theory;job crafting;recovery experience;work demand;work-nonwork conflict
摘要:
Based on the conservation of resources theory, this two-wave study investigated the mediating role of work-nonwork conflict in the relationship between job crafting and employee recovery experience and examined the moderating role of work demands in this relationship. Participants were 486 employees (39.3% male and 60.7% female) from a medical company in the central region of China who responded to a paper-and-pencil survey twice with a 1-month interval. Regression-based results indicated that job crafting positively predicted recovery experience after work through lower work-nonwork conflict. Furthermore, the association between job crafting and work-nonwork conflict was moderated by work demands, such that the effect was stronger for employees with higher work demands. The present study explains how job crafting may improve employees' after-work recovery experience and addresses whether this process could be more significant for employees with higher work demands. The conclusion has practical implications for improving employee recovery experience.
摘要:
With the implementation of China's one-child policy and the increasing living costs, a large number of young people are expected to postpone reaching adulthood. However, little research has explored the patterns of Chinese young people's transition to adulthood. Using a person-centred approach, the current study examined the commonly accepted markers of adulthood status endorsed and attained by 1203 Chinese emerging adults aged 18-29 years. We further compared the distinct adulthood statuses with regard to perceptions of stress and well-being. Latent profile analysis identified four adulthood status profiles: diffused (16.0%), moratorium (45.3%), transitional (23.3%) and achieved (15.4%). Females, those who had no job or came from low family socioeconomics, were more likely to be in the moratorium status. Compared to the other two profiles, participants in diffused and moratorium profiles reported higher levels of perceived stress and lower well-being. These results suggest that there are distinct profiles of Chinese emerging adults on the transition path to adulthood, with a large proportion of them not yet reaching adulthood, and that different statuses of adulthood may be associated with different psychological outcomes.
摘要:
BACKGROUND: Little is known about whether and how contextual appraisals relate to emotion regulation (ER) strategy use across the ultra-high risk and first episode stages of psychosis. The present study extends previous research by investigating the extent to which different appraisal dimensions of the most negative and positive events of the day are associated with ER strategy use in individuals with ultra-high risk (UHR) and first-episode psychosis (FEP). METHOD: Sixty-eight UHR individuals and fifty-five FEP individuals filled out an experience sampling evening questionnaire for six consecutive days, in which their appraisal of intensity, importance and perceived control concerning the most negative or positive event of the day, and the ER strategies they deploy in response to these events were measured. RESULTS: Multilevel mixed effect models showed that intensity appraisal was most closely associated with ER strategy use, as opposed to importance and controllability appraisals. Higher intense negative events were associated with more rumination and social sharing, while less intense negative events were associated with more reappraisal. Higher intense positive events were associated with a greater number of deployed strategies and more efforts in using savoring, expression and social sharing. The UHR and FEP individuals did not significantly differ regarding effects of above-mentioned appraisal dimensions on ER. CONCLUSIONS: These results provide evidence supporting ER flexibility in early psychosis, and event intensity emerged as the dimension most strongly associated with ER. Future research should better account for other situational factors (such as social context) that might affect ER use in psychosis.
摘要:
Previous studies have found working memory (WM) advantages of the pathological smartphone use (PSU) group, but most of which were emphasized in the network-related domain. Whether the advantages can transfer to other domains has yet to be confirmed. In particular, exploring from a brain mechanism perspective is necessary. Using the classical N-back paradigm, this study selected network-related words and neutral words as materials combined with fNIRS to probe the verbal WM characteristics of the PSU group. The results showed that β in channel 3, channel 4, and channel 5 were significantly lower in the PSU group than those in the control group The analysis of the region of interest revealed that the PSU group showed significantly lower β in the l-DLPFC and frontopolar. Granger Causality results showed that functional connectivity between frontopolar and R-DLPFC for the PSU group was significantly higher than for the control group in the network word condition. These results demonstrate that the PSU group has an advantage in WM, transferring from the network-related stimulus to the neutral stimulus. The advantages of network stimulus were related to bidirectional connectivity between frontopolar and R-DLPFC. Also, the l-DLPFC and frontopolar are associated with the cross-material consistency of WM.
期刊:
Journal of Affective Disorders,2023年333:331-341 ISSN:0165-0327
通讯作者:
Chen, H
作者机构:
[Liu, Xinyuan; Chen, Ximei; Chen, Hong; Ling, Ying; Li, Wei; Liu, Yong; Zheng, Anqi] Minist Educ, Key Lab Cognit & Personal SWU, Chongqing 400715, Peoples R China.;[Liu, Xinyuan; Chen, Ximei; Chen, Hong; Ling, Ying; Li, Wei; Chen, H; Liu, Yong; Zheng, Anqi] Southwest Univ, Fac Psychol, 2 Tiansheng Rd, Chongqing 400715, Peoples R China.;[Li, Qingqing] Cent China Normal Univ, Sch Psychol, Wuhan, Peoples R China.;[Chen, Hong] Res Ctr Psychol & Social Dev, Chongqing 400715, Peoples R China.
通讯机构:
[Chen, H ] S;Southwest Univ, Fac Psychol, 2 Tiansheng Rd, Chongqing 400715, Peoples R China.
关键词:
Eating disorder symptoms;Fractional amplitude of low-frequency fluctuations;Functional connectivity;Resting-state fMRI;Type A personality
摘要:
BACKGROUND: Type A personality (TAP) was characterized by impatience, competitiveness, aggressiveness, and hostility. Higher TAP was proved to be associated with more eating disorder symptoms (EDS). While little is known about the underlying neural substrates of TAP and how TAP is linked to EDS at the neural level. METHODS: To investigate the neural basis of TAP, we adopted fractional amplitude of low-frequency fluctuations (fALFF) and resting-state functional connectivity (RSFC) via resting-state functional magnetic resonance imaging (rs-fMRI) (N=1620). Mediation models were examined to explore the relationship between TAP, EDS, and brain activity. RESULTS: TAP was associated with decreased fALFF in the left middle frontal gyrus (MFG) and increased fALFF in the left precentral gyrus (PreCG). Furthermore, TAP was positively correlated to RSFC between the left MFG and left inferior temporal gyrus (ITG) and between the left PreCG and right middle temporal gyrus (MTG). Mediation analysis showed TAP fully mediated the association of the left MFG activity, MFG-ITG connectivity, and PreCG-MTG connectivity with EDS. LIMITATIONS: The cross-sectional design of this study precludes us from specifying the causal relationship in the associations we observed. CONCLUSIONS: Our results suggested spontaneous activity in the left MFG and PreCG is associated with TAP, and even in general sample, people with higher TAP showed more EDS. The present study is the first to investigate the neurobiological underpinnings of TAP in a large sample and further offered new insights into the relation between TAP and EDS from a neural basis perspective.
摘要:
The prevalence of the novel coronavirus (COVID-19) has been considered a major threat to physical and mental health around the world, causing great pressure and mortality threat to most people. The current study aimed to investigate the neurological markers underlying the relationship between perceived mortality threat (PMT) and negative affect (NA). We examined whether the regional amplitude of low-frequency fluctuations (ALFF) and resting-state functional connectivity (RSFC) before the COVID-19 outbreak (October 2019 to December 2019, wave 1) were predictive for NA and PMT during the mid-term of the COVID-19 pandemic (February 22 to 28, 2020, wave 2) among 603 young adults (age range 17-22, 70.8% females). Results indicated that PMT was associated with spontaneous activity in several regions (e.g., inferior temporal gyrus, medial occipital gyrus, medial frontal gyrus, angular gyrus, and cerebellum) and their RSFC with the distributed regions of the default mode network and cognitive control network. Furthermore, longitudinal mediation models showed that ALFF in the cerebellum, medial occipital gyrus, medial frontal gyrus, and angular gyrus (wave 1) predicted PMT (wave 2) through NA (wave 2). These findings revealed functional neural markers of PMT and suggest candidate mechanisms for explaining the complex relationship between NA and mental/neural processing related to PMT in the circumstance of a major crisis.(c) 2023 IBRO. Published by Elsevier Ltd. All rights reserved.
期刊:
PHYSICAL CHEMISTRY CHEMICAL PHYSICS,2023年26(1):130-143 ISSN:1463-9076
通讯作者:
Zhao, YJ
作者机构:
[Zhao, Yunjie; Zeng, Chengwei; Li, Anbang; Zhuo, Chen] Cent China Normal Univ, Inst Biophys, Wuhan 430079, Peoples R China.;[Zhao, Yunjie; Zeng, Chengwei; Li, Anbang; Zhuo, Chen] Cent China Normal Univ, Dept Phys, Wuhan 430079, Peoples R China.;[Jian, Yiren] Dartmouth Coll, Dept Comp Sci, Hanover, NH 03755 USA.;[Zeng, Chen] George Washington Univ, Dept Phys, Washington, DC 20052 USA.
通讯机构:
[Zhao, YJ ] C;Cent China Normal Univ, Inst Biophys, Wuhan 430079, Peoples R China.;Cent China Normal Univ, Dept Phys, Wuhan 430079, Peoples R China.
摘要:
Biological processes such as transcription, repair, and regulation require interactions between DNA and proteins. To unravel their functions, it is imperative to determine the high-resolution structures of DNA-protein complexes. However, experimental methods for this purpose are costly and technically demanding. Consequently, there is an urgent need for computational techniques to identify the structures of DNA-protein complexes. Despite technological advancements, accurately identifying DNA-protein complexes through computational methods still poses a challenge. Our team has developed a cutting-edge deep-learning approach called DDPScore that assesses DNA-protein complex structures. DDPScore utilizes a 4D convolutional neural network to overcome limited training data. This approach effectively captures local and global features while comprehensively considering the conformational changes arising from the flexibility during the DNA-protein docking process. DDPScore consistently outperformed the available methods in comprehensive DNA-protein complex docking evaluations, even for the flexible docking challenges. DDPScore has a wide range of applications in predicting and designing structures of DNA-protein complexes. Biological processes such as transcription, repair, and regulation require interactions between DNA and proteins.
摘要:
Time pressure affects multiple cognitive processes but how it affects attention capture remains unclear. Two experiments were carried out in the present study to assess whether time pressure prevents attention from capturing by salient distractors and explore the underlying neural mechanisms using functional near-infrared spectroscopy. The results of behavioral tests showed that the singleton effect decreased (Experiment 2) or even disappeared (Experiment 1) when the subject was under time pressure. Neuroimaging data showed that under time pressure, a salient distractor elicited greater activation in the left middle frontal gyrus/inferior frontal gyrus and bilateral superior parietal lobule, brain areas that are thought to be involved in cognitive inhibition and control of spatial attentional shifts. These findings suggest that the reduction or disappearance of the singleton effect under time pressure results from enhanced inhibition of and/or accelerated disengagement from salient distractors.
期刊:
Journal of Hazardous Materials,2023年457:131837 ISSN:0304-3894
通讯作者:
Lu, C
作者机构:
[Liu, Zijing; Yang, Wenhui; Lu, Chan; Liao, Hongsen] Cent South Univ, XiangYa Sch Publ Hlth, Changsha 410078, Hunan, Peoples R China.;[Wang, Faming] Katholieke Univ Leuven, Dept Biosyst, Div Anim & Human Hlth Engn, B-3001 Leuven, Belgium.;[Wang, Faming] Xian Univ Sci & Technol, Occupat Safety & Publ Hlth Grp, Xian 710054, Shanxi, Peoples R China.;[Li, Bin] Cent China Normal Univ, Sch Psychol, Wuhan 430070, Hubei, Peoples R China.
通讯机构:
[Lu, C ] C;Cent South Univ, XiangYa Sch Publ Hlth, Changsha 410078, Hunan, Peoples R China.
关键词:
Childhood pneumonia;Gaseous air pollution;Particulate matters;Postnatal;Pregnancy
摘要:
BACKGROUND: Despite mounting evidence linked pneumonia with air pollution, it is unclear what main pollutant(s) exposure in which critical window(s) play a key role in pneumonia. OBJECTIVE: To examine effects of intrauterine and post-natal exposure to air pollution on children's doctor-diagnosed pneumonia (DDP). METHODS: A combination of cross-sectional and retrospective cohort study was conducted at Changsha, China during 2019-2020. Personal exposure to outdoor air pollutants at each child's home address was estimated using inverse distance weighted (IDW) method based on data from 10 air quality monitoring stations. Associations between personal air pollution exposure and DDP were evaluated. RESULTS: Children's DDP was associated with intrauterine and post-natal exposure to PM(2.5), PM(2.5-10), and PM(10), adjusted ORs (95% CI) of 1.17 (1.04-1.30), 1.09 (1.01-1.17), and 1.07 (1.00-1.14) for IQR increase in intrauterine exposure and 1.12 (1.02-1.22), 1.13 (1.06-1.21), and 1.28 (1.16-1.41) for post-natal exposure. Intrauterine PM(2.5) exposure and post-natal PM(10) exposure were associated with a higher risk of pneumonia. We identified the 2nd trimester, 3rd trimester, and first year as critical windows respectively for PM(2.5), PM(2.5-10), and PM(10) exposure. Daytime exposure to traffic-related air pollution especially during early life increased DDP. CONCLUSION: Intrauterine and post-natal exposure to particulate matters played a dominant role in children's DDP.
期刊:
CYBERPSYCHOLOGY BEHAVIOR AND SOCIAL NETWORKING,2023年26(8):631-639 ISSN:2152-2715
通讯作者:
Zongkui Zhou
作者机构:
Key Laboratory of Adolescent Cyberpsychology and Behavior (CCNU), Ministry of Education, Wuhan, China.;School of Psychology, Central China Normal University, Wuhan, China.;[Wenya Peng] Faculty of Psychology, Beijing Normal University, Beijing, China.;Address correspondence to: Prof. Zongkui Zhou, School of Psychology, Central China Normal University, Wuhan 430079, China;[Yuxiao Liu; Min Cao; Shujing Zhang; Ji Peng] Key Laboratory of Adolescent Cyberpsychology and Behavior (CCNU), Ministry of Education, Wuhan, China.<&wdkj&>School of Psychology, Central China Normal University, Wuhan, China.
通讯机构:
[Zongkui Zhou ] A;Address correspondence to: Prof. Zongkui Zhou, School of Psychology, Central China Normal University, Wuhan 430079, China<&wdkj&>Key Laboratory of Adolescent Cyberpsychology and Behavior (CCNU), Ministry of Education, Wuhan, China.<&wdkj&>School of Psychology, Central China Normal University, Wuhan, China.
摘要:
One of the far-reaching impacts of the COVID-19 pandemic is that it has become the fertile soil of cyberchondria. Adolescents' mental health was severely hit by this by-product of the COVID-19 pandemic both due to the direct effects and its indirect effects on security. This study investigated whether and how cyberchondria was associated with Chinese adolescents' mental health (i.e., well-being and depressive symptoms). Based on a large Internet sample (N = 1,108, 67.5 percent female, M(age) = 16.78 years), cyberchondria, psychological insecurity, mental health, and a series of covariates were assessed. Preliminary analyses were conducted in SPSS Statistics software and main analyses were conducted in Mplus. Path analyses indicated that (a) cyberchondria was negatively associated with well-being (b = -0.12, p = 0.001) and positively associated with depressive symptoms (b = 0.17, p < 0.001); (b) psychological insecurity could fully mediate the association between cyberchondria and mental health (indirect effect (well-being) = -0.15, 95% confidence interval [CI -0.19 to -0.12] and indirect effect (depressive symptoms) = 0.15, 95% CI [0.12 to 0.19]); (c) the two dimensions (social insecurity and uncertainty) of psychological insecurity could play the mediating role in the associations between cyberchondria and mental health, uniquely and parallelly; and (d) these results did not vary by gender. This study suggests that cyberchondria may arouse individuals' psychological insecurity about interpersonal interaction and the development of events, which ultimately decreases their well-being and increases the risk of depressive symptoms. These findings facilitate the establishment and implementation of relevant prevention and intervention programs.
期刊:
International Journal of Psychophysiology,2023年188:1-11 ISSN:0167-8760
通讯作者:
Ming Peng
作者机构:
[Peng, Ming; Chen, Tianlong; Yang, Xiaoying; Tang, Rui] Cent China Normal Univ, Sch Psychol, Minist Educ, Key Lab Adolescent Cyberpsychol & Behav, Wuhan, Peoples R China.;[Peng, Ming; Chen, Tianlong; Yang, Xiaoying; Tang, Rui] Cent China Normal Univ, Sch Psychol, 152 Luoyu Rd, Wuhan 430079, Hubei, Peoples R China.;[Peng, Ming] Key Lab Human Dev & Mental Hlth Hubei Prov, Wuhan 430079, Peoples R China.;[Cai, Mengfei] Manhattanville Coll, Dept Psychol, New York, NY USA.
通讯机构:
[Ming Peng] K;Key Laboratory of Adolescent Cyberpsychology and Behavior of the Ministry of Education and School of Psychology, Central China Normal University, Wuhan, China<&wdkj&>School of Psychology, Central China Normal University, Wuhan, China<&wdkj&>Key Laboratory of Human Development and Mental Health of Hubei Province, Wuhan 430079, China
关键词:
EEG;ERP;Fairness consideration;Moral transgression;Ultimatum game
摘要:
People tend to dislike and punish unfair behaviors in social interactions, and this disposition may be moderated by the characteristics of their interaction partner. We used a modified ultimatum game (UG) to investigate players' responses to fair and unfair offers from proposers described as having performed either a moral transgression or a neutral behavior, and recorded an electroencephalogram. The participants' behavior in the UG suggests that people quickly demand more fairness from proposers who have committed moral transgressions rather than neutral behavior. Event-related potentials (ERPs) revealed a significant effect of offer type and of proposer type on P300 activity. The prestimulus α-oscillation power in the neutral behavior condition was significantly lower than that in the moral transgression condition. The post-stimulus β-event-related synchronization (β-ERS) was larger for the moral transgression condition than the neutral behavior condition in response to the least fair offers, and larger for neutral behavior than the moral transgression condition in response to the fairest offers. In summary, β-ERS was influenced by both proposer type and offer type, which revealed different neural responses to the offer from either a morally transgressive or a neutral behavior proposer.
期刊:
Journal of Interpersonal Violence,2023年38(11-12):7355-7382 ISSN:0886-2605
通讯作者:
Dongping Li
作者机构:
[Liu, Jiaoyu; Li, Dongping; Liu, Yuxiao; Lv, Yaxin] Cent China Normal Univ, Wuhan, Peoples R China.;[Jia, Jichao] Beijing Normal Univ, Beijing, Peoples R China.;[Zhai, Boyu] Chinese Acad Sci, Beijing, Peoples R China.;[Li, Dongping] Cent China Normal Univ, Sch Psychol, 152 Luoyu Rd, Wuhan 430079, Hubei, Peoples R China.
通讯机构:
[Dongping Li] C;Central China Normal University, Wuhan, China
摘要:
Considerable developmental research has shown an association between peer victimization and subjective well-being among adolescents. However, the mediating processes and protective factors that constrain this association are less understood. To fill these gaps, we investigated whether self-esteem mediates the association between peer victimization and subjective well-being and whether forgiveness moderates the direct and indirect associations of peer victimization with adolescents' subjective well-being via self-esteem. A large sample of 2,758 adolescents (M(age) = 13.53 years, SD = 1.06) from 10 middle schools in China participated in this study. Participants provided data on demographic variables, peer victimization, self-esteem, forgiveness, and subjective well-being by answering anonymous questionnaires. After controlling for demographic covariates, we found that self-esteem mediated the relationship between peer victimization and subjective well-being. Furthermore, as a protective factor, forgiveness moderated the relationship between peer victimization and self-esteem. Consistent with the protective-reactive model, when adolescents experienced more peer victimization, those with higher forgiveness levels exhibited a greater decline in self-esteem, and low self-esteem was then associated with decreased subjective well-being. These findings demonstrate the utility of examining both mediating and moderating factors in this relationship and highlight the negative impact of peer victimization on adolescent self-worth and the limited role of forgiveness as a protective factor.
摘要:
The world can be represented by two layers of information: How it appears on the outside (outward appearance) and what it is on the inside (inner state). To what extent an outward appearance is assumed to reflect the inner state is fundamental to social inference and judgments. Conceptualizing inference in terms of the relationship between the outward appearance and the inner state generates an integrative interpretation for a wide range of phenomena. We showed that Chinese were more likely than Euro-Canadians to make inference of inner state that deviated from outward appearance, whereas Euro-Canadians were more likely than Chinese to infer a convergence between outward appearance and inner state (Studies 1-5). We observed these cross-cultural patterns in various contexts involving people or physical structures. Individual differences in correspondence bias or response bias did not explain these patterns. The lay belief that outward appearance can be misleading mediated the cultural effects (Study 4). To probe the underlying process, two additional experiments showed that highlighting the misleading nature of appearance, but not highlighting the power of the situation, reduced Americans' beliefs (Study 6) and inference (Study 7) that the outward appearance reflects the inner state. By focusing on the assumed relationship between the outward appearance and inner state, these findings provide a unique angle for understanding cross-cultural phenomena and have practical implications in daily life. (PsycInfo Database Record (c) 2023 APA, all rights reserved).
期刊:
PHYSICAL CHEMISTRY CHEMICAL PHYSICS,2023年25(41):27967-27980 ISSN:1463-9076
通讯作者:
Zhao, YJ;Gong, Z
作者机构:
[Ning, Shangbo; Zhao, Yunjie; Li, Anbang] Cent China Normal Univ, Dept Phys, Wuhan 430079, Peoples R China.;[Ning, Shangbo; Zhao, Yunjie; Li, Anbang] Cent China Normal Univ, Inst Biophys, Wuhan 430079, Peoples R China.;[Liu, Maili; Gong, Zhou; Sun, Min; Dong, Xu] Chinese Acad Sci, Innovat Acad Precis Measurement Sci & Technol, State Key Lab Magnet Resonance & Atom Mol Phys, Wuhan 430071, Hubei, Peoples R China.;[Zeng, Chen] George Washington Univ, Dept Phys, Washington, DC 20052 USA.
通讯机构:
[Zhao, YJ ; Gong, Z ] C;Cent China Normal Univ, Dept Phys, Wuhan 430079, Peoples R China.;Cent China Normal Univ, Inst Biophys, Wuhan 430079, Peoples R China.;Chinese Acad Sci, Innovat Acad Precis Measurement Sci & Technol, State Key Lab Magnet Resonance & Atom Mol Phys, Wuhan 430071, Hubei, Peoples R China.
摘要:
Designing inhibitors for RNA is still challenging due to the bottleneck of maintaining the binding interaction of inhibitor-RNA accompanied by subtle RNA flexibility. Thus, the current approach usually needs to screen thousands of candidate inhibitors for binding. Here, we propose a dynamic geometry design approach to enrich the hits with only a tiny pool of designed geometrically compatible scaffold candidates. First, our method uses graph-based tree decomposition to explore the complementarity rigid binding cyclic peptide and design the amino acid side chain length and charge to fit the RNA pocket. Then, we perform an energy-based dynamical network algorithm to optimize the inhibitor-RNA hydrogen bonds. Dynamic geometry-guided design yields successful inhibitors with low micromolar binding affinity scaffolds and experimentally competes with the natural RNA chaperone. The results indicate that the dynamic geometry method yields higher efficiency and accuracy than traditional methods. The strategy could be further optimized to design the length and chirality by adopting nonstandard amino acids and facilitating RNA engineering for biological or medical applications. Designing inhibitors for RNA is still challenging due to the bottleneck of maintaining the binding interaction of inhibitor-RNA accompanied by subtle RNA flexibility.
通讯机构:
[Li, Y ] C;Cent China Normal Univ, Key Lab Adolescent Cyberpsychol & Behav CCNU, Minist Educ, 152 Luoyu St, Wuhan 430079, Hubei, Peoples R China.;Cent China Normal Univ, Sch Psychol, 152 Luoyu St, Wuhan 430079, Hubei, Peoples R China.
关键词:
Openness;Social anxiety;Active social networking site use;Passive social networking site use;Self-evaluation
摘要:
As social networking sites (SNSs) with diverse functions gradually become an important social place for modern people, openness, as a personality trait that represents the willingness to consider diverse things, will be more likely to affect people’s cognitive and emotional experience (e.g., social anxiety) in social interactions. This study examined the relationship between openness and social anxiety and the underlying psychological mechanism in the internet age based on the cognitive-behavioral model of social anxiety. This cross‑sectional survey study conducted a questionnaire survey of 522 college students from two provinces in China (191 male; age range 18–25; M = 20.76, SD = 1.34). The results showed that openness is negatively related to social anxiety. Self-evaluation and passive SNS use independently mediate the relationship between openness and social anxiety, respectively. Moreover, openness is associated with social anxiety both through the chain mediating roles of active SNS use and self-evaluation and through the chain mediating roles of passive SNS use and self-evaluation. Openness is negatively associated with social anxiety, and the different ways of SNS use and self-evaluation are the underlying mechanisms. These results provide insights into the clinical treatment of social anxiety and how to benefit from online interactions.
摘要:
Binocular rivalry, a visual perception phenomenon where two or more percepts alternate every few seconds when distinct stimuli are presented to the two eyes, has been reported as a biomarker in several psychiatric disorders. It is unclear whether abnormalities of binocular rivalry in depression could occur when emotional rivaling stimuli are used, and if so, whether an emotional binocular rivalry test could provide a trait-dependent or state-dependent biomarker. In the current study, 34 individuals with subthreshold depression and 31 non-depressed individuals performed a binocular rivalry task associated with implicit emotional processing. Participants were required to report their perceived orientations of the rival gratings in the foreground and to neglect emotional face stimuli in the background. The participants were retested after an approximately 4-month time interval. Compared to the non-depressed group, the subthreshold depression group showed significantly longer perceptual dominance durations of the grating with emotional faces as the background (i.e., implicit emotional dominance) at the initial assessment. However, the abnormality was not found at the follow-up assessment. More importantly, we found smaller changes in depressive severity at the follow-up assessment for individuals displaying longer emotional dominance at the initial assessment than for individuals with weaker emotional dominance. The current emotional binocular rivalry test may provide an objective, state-dependent biomarker for distinguishing individuals with subthreshold depression from non-depressed individuals.
期刊:
JOURNAL OF BEHAVIORAL ADDICTIONS,2023年12(4):907-919 ISSN:2062-5871
通讯作者:
Zhang, W
作者机构:
[Zhang, Wei; Li, Ziyi; Du, Yunjing] Cent China Normal Univ, Sch Psychol, Wuhan, Hubei, Peoples R China.;[Zhang, Wei; Li, Ziyi; Du, Yunjing] Minist Educ, Key Lab Adolescent Cyberpsychol & Behav CCNU, Wuhan, Peoples R China.;[Zhang, Wei; Li, Ziyi; Du, Yunjing] Cent China Normal Univ, Hubei Human Dev & Mental Hlth Key Lab, Wuhan, Hubei, Peoples R China.;[Du, Yunjing] Multidisciplinary Digital Publishing Inst, Basel, Switzerland.
通讯机构:
[Zhang, W ] C;Cent China Normal Univ, Sch Psychol, Wuhan, Hubei, Peoples R China.;Minist Educ, Key Lab Adolescent Cyberpsychol & Behav CCNU, Wuhan, Peoples R China.;Cent China Normal Univ, Hubei Human Dev & Mental Hlth Key Lab, Wuhan, Hubei, Peoples R China.
关键词:
internet use disorder;intertemporal decision-making;risky decision-making;functional connectivity;OFC;dlPFC
摘要:
BACKGROUND AND AIMS: The intertemporal and risk decision-making impairments are vital cognitive mechanisms in internet use disorder (IUD). However, the underlying neural mechanisms for these two decision-making dysfunctions in individuals with IUD remain unclear. METHODS: This study employed Functional Near-Infrared Spectroscopy (fNIRS) to record changes in blood oxygen concentration in the prefrontal cortex of individuals with IUD during intertemporal and risk decision-making tasks. RESULTS: The findings revealed that the intertemporal decision-making deficits in IUD group were primarily associated with reduced activation in the left dorsolateral prefrontal cortex (dlPFC) and orbitofrontal cortex (OFC) and FC from the left dlPFC to the right dlPFC. On the other hand, risk decision-making impairments were linked to decreased OFC activation and weakened functional connectivity from the left dlPFC to the right dlPFC and OFC. DISCUSSIONS AND CONSLUSIONS: These results suggested that while there were common neural mechanisms underlying intertemporal and risk decision-making impairments in individuals with IUD, specific neural foundations existed for each type of dysfunction.