摘要：
Fourteen novel 3-substituted-5-methyl-4-methylene-7-alkylsulfanyl-3,4-dihydro-pyrido[4,3-d]pyrimidine-8-carbonitriles, compounds 4a–n, were designed and synthesized via a facile regioselective cyclization process. The intermediate 2 reacted with triethyl orthoformate (molar ratio is 1:4) in the presence of acetic anhydride to give formamidate 3, which was cycled to 4 regioselectively upon addition of different amines at mild condition. The structures of compounds 4a–n were confirmed by IR, 1H NMR, MS and elemental analysis. The preliminary bioassay indicated that some compounds possess significant herbicidal activity against the roots of rape and barnyard grass, especially when the fluorine atom was introduced to the para position of the substitutents on pyrimidine ring; some compounds showed fungicidal activities against Rhizoctonia solani, Botrytis cinereapers, Gibberella zeae, Dothiorella gregaria, Colletotrichum gossypii as well, and the introduction of fluorine has negative effect on the antifungal activities.
摘要：
Five new xanthones, namely Garcinexanthones A-E (1-5), were isolated from the barks of Garcinia xanthochymus. Their structures were elucidated by spectral analysis, primarily NMR, MS, and UV. The complete assignments of the H-1 NMR and C-13 NMR chemical shifts for the compounds were achieved by using D-1 and D-2 NMR techniques, including DEPT, HSQC, and HMBC NMR experiments. Copyright (C) 2008 John Wiley & Sons, Ltd.
摘要：
A new and facile route to synthesize 2-substituted pyrano[2,3-d]pyrimidin-4(3H)-ones derivatives using iminophosphorane from easily obtained starting materials was investigated and expanded.
期刊：
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS,2008年183(2-3):712-713 ISSN：1042-6507
通讯作者：
He, Hong-Wu
作者机构：
[He, Hong-Wu; Li, Yan-Jun] Cent China Normal Univ, Key Lab Pesticide & Chem Biol, Minist Educ, Wuhan 430079, Peoples R China.
通讯机构：
[He, Hong-Wu] C;Cent China Normal Univ, Key Lab Pesticide & Chem Biol, Minist Educ, Wuhan 430079, Peoples R China.
会议名称：
17th International Conference on Phosphorus Chemistry
会议时间：
APR 15-21, 2007
会议地点：
Xiamen, PEOPLES R CHINA
会议主办单位：
[Li, Yan-Jun;He, Hong-Wu] Cent China Normal Univ, Key Lab Pesticide & Chem Biol, Minist Educ, Wuhan 430079, Peoples R China.
关键词：
Fluoro-substituted;phosphonate;synthesis
摘要：
Eight of novel fluoro-substituted phosphonate derivatives were synthesized and the preliminary bioassay indicated that these compounds exhibited herbicidal activities.
摘要：
Phosphorus-containing agrochemicals have made a major contribution to the advancement of agriculture in China. Current status about production and usages of organophosphorus agrochemicals in China is reviewed in this article. Development of new organophosphorus agrochemicals including insecticide, herbicide, and anti-TMV agent in recent years is introduced. Recent progress in research and development of α -(Substituted phenoxyacetoxy)alkylphosphonates is then described: α -(Substituted phenoxyacetoxy)alkylphosphonate II as a kind of potential agrochemicals was found on the basis of the study of a series of α -oxophosphonic acid derivatives I in our Lab. Some compounds II were demonstrated as effective inhibitors of pyruvate dehydrogenase complex from plant (in vitro) and showed notable herbicidal activity against broad-leaved weeds. Compound HW02 as a potential herbicide was evaluated and developed.
作者：
Liu Ai-Ping*;Feng Qiu-Ju;Hu Chun-Hua;He Hai-Jun;Wang Ting-Jin;...
期刊：
有机化学,2008年28(3):531-534 ISSN：0253-2786
通讯作者：
Liu Ai-Ping
作者机构：
[Wang Ting-Jin; He Hai-Jun; Feng Qiu-Ju; Hu Chun-Hua; Liu Ai-Ping] Hunan Res Inst Chem Ind, Natl Engn Res Ctr Agrochem, Changsha 410007, Peoples R China.;[Wang Ting-Jin; Liu Yang; Feng Qiu-Ju; Hu Chun-Hua; He Hong-Wu] Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China.;[He Hai-Jun] Hunan Normal Univ, Coll Chem & Chem Engn, Changsha 410081, Peoples R China.
通讯机构：
[Liu Ai-Ping] H;Hunan Res Inst Chem Ind, Natl Engn Res Ctr Agrochem, Changsha 410007, Peoples R China.
作者机构：
[He, Hong-Wu; Li, Wen-Ying] Cent China Normal Univ, Coll Chem, Key Lab Pesticides & Chem Biol, Minist Educ, Wuhan 430079, Peoples R China.;[Lu, Long; Mao, Li-Sheng] Chinese Acad Sci, Shanghai Inst Organ Chem, Shanghai 200032, Peoples R China.;[Lu, Long] Chinese Acad Sci, Shanghai Inst Organ Chem, 345 Lingling Lu, Shanghai 200032, Peoples R China.
通讯机构：
[Lu, Long] C;Chinese Acad Sci, Shanghai Inst Organ Chem, 345 Lingling Lu, Shanghai 200032, Peoples R China.
摘要：
In the title compound, [Ir(C10H8N3)(C11H8N)2], the Ir center is octa-hedrally coordinated by the three chelating ligands, with two cyclo-metalated 2-pyridylphenyl ligands [Ir - N = 2.049 (5) and 2.030 (5) Å; Ir - C = 2.016 (6) and 2.012 (6) Å] and a bidentate 2-(phenyl-diazen-yl)pyrrolate ligand [Ir - N = 2.204 (5) and 2.079 (5) Å]. The Ir - N(diazen-yl) bond is longer than the Ir - N(pyrrolate) bond. The structure is stabilized by aromatic π-π stacking, the shortest parallel distance between ring centroids being 3.426 (8) Å..
摘要：
Fourteen of phosphonates containing quinoline were synthesized and the preliminary bioassay indicated that these compounds exhibited a little better fungicidal and lower herbicidal activities than the starting compound Quinclorac.
作者机构：
[He, Hong-Wu; Peng, Hao] Cent China Normal Univ, Coll Chem, Key Lab Pesticides & Chem Biol, Wuhan 430079, Peoples R China.
通讯机构：
[He, Hong-Wu] C;Cent China Normal Univ, Coll Chem, Key Lab Pesticides & Chem Biol, Wuhan 430079, Peoples R China.
摘要：
In the title compound, C4H12N+center dot C11H12Cl2O6P-center dot C3H6O, all bond lengths and angles are normal. Three ammonium H atoms participate in N-H center dot center dot center dot O hydrogen bonds, which stabilize the crystal packing along with weak intermolecular C-H center dot center dot center dot O interactions.
摘要：
Eighteen novel 5-alkylamino-6-aryl-3-phenyl-2-thioxo-2,3-dihydrothiazolo[4,5-d]pyrimidin-7(6H)-ones 5a-r were designed and easily synthesized via a tandem aza-Wittig reaction. Treatment of iminophosphorane 2 with aromatic isocyanate gave carbodiimide 3, which reacted with fluoro-substituted alkylamines to provide the title compounds in 65-87% isolated yields using sodium ethoxide as catalyst. All compounds 5 were confirmed by IR, H-1 NMR, MS and elemental analysis, and compound 5p was further analyzed by single-crystal X-ray diffraction. The preliminary bioassay indicated that some compounds showed significant inhibition activities against the root growth of rape and barnyard grass at a dosage of 100 mg/L. (C) 2007 Elsevier B.V. All rights reserved.
