A photo-responsive macroscopic switch constructed using a chiral azo-calix[4]arene functionalized silicon surface
作者：
Pang, Huan;Xu, Pingping;Li, Chonglu;Zhan, Yibei;Zhang, Zengyuan;...
期刊：
Chemical Communications ,2018年54(24):2978-2981 ISSN：1359-7345
通讯作者：
Sun, Yao
作者机构：
[Xu, Pingping; Yang, Guangfu; Li, Haibing; Pang, Huan; Zhan, Yibei; Zhang, Wanshu; Zhang, Zengyuan; Sun, Yao; Li, Chonglu] Cent China Normal Univ, Key Lab Pesticide & Chem Biol, Hubei Int Sci & Technol Cooperat Base Pesticide &, Minist Educ,Coll Chem, Wuhan 430079, Hubei, Peoples R China.
通讯机构：
[Sun, Yao] C;Cent China Normal Univ, Key Lab Pesticide & Chem Biol, Hubei Int Sci & Technol Cooperat Base Pesticide &, Minist Educ,Coll Chem, Wuhan 430079, Hubei, Peoples R China.
摘要：
A photo-responsive macroscopic switch was fabricated using a chiral azo-calix[4]arene derivative (FC4AD) functionalized silicon surface and exhibited selective and reversible recognition of (1R,2S)-1-amino-2-indanol through the variation of wettability. This photo-responsive device may have wide applications in controlled release of chiral drugs and in biosensors.
语种：
英文
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Alanine-Based Chiral Metallogels via Supramolecular Coordination Complex Platforms: Metallogelation Induced Chirality Transfer
作者：
Sun, Yue;Li, Shuai;Zhou, Zhixuan;Saha, Manik Lal;Datta, Sougata;...
期刊：
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY ,2018年140(9):3257-3263 ISSN：0002-7863
通讯作者：
Li, Haibing;Stang, Peter J.;Liu, Minghua
作者机构：
[Sun, Yue; Tian, Demei; Li, Haibing] Cent China Normal Univ, Key Lab Pesticide & Chem Biol CCNU, Coll Chem, Minist Educ, Wuhan 430079, Hubei, Peoples R China.;[Sun, Yue; Yan, Xuzhou; Tian, Demei; Zhang, Mingming; Saha, Manik Lal; Stang, Peter J.; Datta, Sougata; Zhou, Zhixuan] Univ Utah, Dept Chem, 315 South 1400 East,Room 2020, Salt Lake City, UT 84112 USA.;[Li, Shuai; Liu, Minghua] Chinese Acad Sci, Inst Chem, CAS Key Lab Colloid Interface & Chem Thermodynam, Beijing Natl Lab Mol Sci, Beijing 100190, Peoples R China.;[Wang, Heng; Wang, Lei; Li, Xiaopeng] Univ S Florida, Dept Chem, 4202 East Fowler Ave, Tampa, FL 33620 USA.;[Li, Haibing] Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol CCNU, Wuhan 430079, Hubei, Peoples R China.
通讯机构：
[Li, Haibing; Liu, Minghua] C;[Stang, Peter J.] U;Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol CCNU, Wuhan 430079, Hubei, Peoples R China.;Univ Utah, Dept Chem, 315 South 1400 East,Room 2020, Salt Lake City, UT 84112 USA.;Chinese Acad Sci, Inst Chem, CAS Key Lab Colloid Interface & Chem Thermodynam, Beijing Natl Lab Mol Sci, Beijing 100190, Peoples R China.
摘要：
Chiral self-assemblies constantly attract great interest because of their potential to provide insight into biological systems and materials science. Herein we report on the efficient preparation of alanine-based chiral metallacycles, rhomboids 1<sup>D</sup>and 1<sup>L</sup>and hexagons 2<sup>D</sup>and 2<sup>L</sup>using a Pt(II) a pyridyl directional bonding approach. The metallacycles are subsequently assembled into nanospheres at low concentration, that generate chiral metallogels at high concentration driven by hydrogen bonding, hydrophobic and π-πinteractions. The gels consist of microscopic chiral nanofibers with well-defined helicity, as confirmed by circular dichroism (CD) and scanning (SEM) and transmission electron (TEM) microscopies. Given these results, we expect this technique will not only unlock interesting new approaches to understand homochirality in nature but also allow the design of versatile soft materials containing chiral supramolecular cores.<br/> ©2017 American Chemical Society.
语种：
英文
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Macroscopic Chiral Recognition by Calix[4]arene-Based Host–Guest Interactions
作者：
Quan, Jiaxin;Nie, Guanrong;Xue, Hong;Luo, Li;Zhang, Ruiping* ;...
期刊：
CHEMISTRY-A EUROPEAN JOURNAL ,2018年24(58):15502-15506 ISSN：0947-6539
通讯作者：
Li, Haibing;Zhang, Ruiping
作者机构：
[Xue, Hong; Luo, Li; Li, Haibing; Nie, Guanrong; Quan, Jiaxin] Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol CCNU, Wuhan 430079, Hubei, Peoples R China.;[Zhang, Ruiping] Shanxi Med Univ, Imaging Dept, Affiliated Tumor Hosp, Taiyuan 030001, Shanxi, Peoples R China.
通讯机构：
[Li, Haibing] C;[Zhang, Ruiping] S;Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol CCNU, Wuhan 430079, Hubei, Peoples R China.;Shanxi Med Univ, Imaging Dept, Affiliated Tumor Hosp, Taiyuan 030001, Shanxi, Peoples R China.
关键词：
chiral matching;host–guest systems;macroscopic recognition;supramolecular chemistry;surface chemistry
摘要：
Chiral recognition as an intrinsic process of life, plays a crucial role in chemical systems, and further forms various architectures in the resulted functional materials. So far, relevant studies were focused on the recognition of chiral molecules. However, weak chiral interactions transformed into macroscopic recognition, for example, for chiral drug droplets, is much more crucial due to its applicability in controlling the drugs′ selective delivery and for their enantiomer separation. In this report, chiral calix[4]arene was introduced onto a surface for the selective recognition of (S)-naproxen droplet through host–guest interactions. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim
语种：
英文
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Macroscopic visual detection of phoxim by calix[4]arene-based host-guest chemistry
作者：
Feng, Jiyang;Yang, Guanxing;Mei, Yuxiao;Cao, Xianliang;Wang, Yecan;...
期刊：
Sensors and Actuators B-Chemical ,2018年271:264-270 ISSN：0925-4005
通讯作者：
Li, Haibing;Lu, Qingye
作者机构：
[Cao, Xianliang; Yang, Guanxing; Li, Haibing; Mei, Yuxiao; Feng, Jiyang] Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol CCNU, Wuhan 430079, Hubei, Peoples R China.;[Lu, Qingye; Wang, Yecan] Univ Calgary, Dept Chem & Petr Engn, Calgary, AB T2N 1N4, Canada.
通讯机构：
[Li, Haibing] C;[Lu, Qingye] U;Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol CCNU, Wuhan 430079, Hubei, Peoples R China.;Univ Calgary, Dept Chem & Petr Engn, Calgary, AB T2N 1N4, Canada.
关键词：
Calix[4]arene;Pesticide;Si-surface;Wettability sensor
摘要：
A new coumarin-appended calix[4]arene (C4C2) was synthesized and a self-assembled monolayers modified silicon surface (C4C2-SAMs) was constructed via click chemistry. The water contact angle measurements show that these C4C2-SAMs exhibited highly selective macroscopic response towards phoxim with a detection limit of 1 x 10(-6) M. UV-vis and fluorescence titration further confirmed the high recognition selectivity of the C4C2-SAMs towards phoxim. The C4C2-SAMs are capable of detecting phoxim in real river water samples through visual water contact angle change, suggesting that the C4C2-SAMs can be used as a convenient and effective sensor for phoxim.
语种：
英文
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PEGylation Regulates Self-Assembled Small-Molecule Dye–Based Probes from Single Molecule to Nanoparticle Size for Multifunctional NIR-II Bioimaging
作者：
Ding, Feng;Li, Chonglu;Xu, Yuling;Li, Jiaxin;Li, Haibing;...
期刊：
Advanced Healthcare Materials ,2018年7(23):1800973- ISSN：2192-2640
通讯作者：
Yang, Guangfu;Sun, Yao
作者机构：
[Xu, Yuling; Yang, Guangfu; Li, Haibing; Yang, GF; Sun, Yao; Ding, Feng; Li, Chonglu] Cent China Normal Univ, Int Joint Res Ctr Intelligent Biosensor Technol &, Key Lab Pesticides & Chem Biol, Minist Educ,Chem Biol Ctr,Coll Chem, Wuhan 430079, Hubei, Peoples R China.;[Li, Jiaxin] Nanjing Univ, State Key Lab Analyt Chem Life Sci, Nanjing 210023, Jiangsu, Peoples R China.
通讯机构：
[Yang, GF; Sun, Y] C;Cent China Normal Univ, Int Joint Res Ctr Intelligent Biosensor Technol &, Key Lab Pesticides & Chem Biol, Minist Educ,Chem Biol Ctr,Coll Chem, Wuhan 430079, Hubei, Peoples R China.
关键词：
bioimaging;PEGylation;second near-infrared window;self-assembly;small-molecule dyes
摘要：
To date, small-molecule dye–based probes have been at the forefront of research in biomedical imaging, especially in the second near-infrared (NIR-II) window (1.0–1.7 µm). However, how to precisely regulate the synthesized size of NIR-II organic dye–based probes remains challenging. Moreover, systematic studies on whether the size of NIR-II probes affects optical/pharmacokinetic properties are still rare. Here, an ingenious PEGylation strategy is developed to regulate the self-assembly size of organic dye–based (CH1055 scaffold) NIR-II probes (SCH1–SCH4) from nanoparticles to the single molecule, and the relationship between their size and chemical/physical properties is thoroughly investigated. Based on their own merits, nanoprobe SCH1 (≈170 nm), with outstanding fluorescent brightness (quantum yield ≈0.14%), performs accurate tracing of the lymphatic system as well as identification of vessel networks in mice brains with excellent signal-to-background ratio images. Meanwhile, rapidly excreted SCH4, showing fast and high passive liver tumor uptake and promising tumor/normal tissue ratios (>7), is capable of facilitating precise image-guided tumor surgery, and also demonstrates the first example of the assessment of liver fibrosis in the NIR-II window. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
语种：
英文
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Single nanochannel platform for detecting chiral drugs
作者：
Boussouar, Imene;Chen, Qianjin;Chen, Xue;Zhang, Yulun;Zhang, Fan;...
期刊：
Analytical Chemistry ,2017年89(2):1110-1116 ISSN：0003-2700
通讯作者：
Li, Haibing
作者机构：
[Boussouar, Imene; Li, Haibing; Zhang, Fan; Tian, Demei; Chen, Xue] Cent China Normal Univ, Coll Chem, Key Lab Pesticide & Chem Biol CCNU, Minist Educ, Wuhan 430079, Peoples R China.;[Zhang, Yulun; White, Henry S.; Chen, Qianjin] Univ Utah, Dept Chem, 315 S,1400 E, Salt Lake City, UT 84112 USA.
通讯机构：
[Li, Haibing] C;Cent China Normal Univ, Coll Chem, Key Lab Pesticide & Chem Biol CCNU, Minist Educ, Wuhan 430079, Peoples R China.
摘要：
Chiral drugs play an essential role in medical and biochemical systems, and thus enantioselective analysis of chiral molecules has become a central focus in chemical, biological, medical, and pharmaceutical research. The design of chiral drug-detecting systems is a long-term and challenging task. Here we report the use of a modification-free nanochannel method for enantioselective recognition of S-naproxen from R-naproxen using N-acetyl-L-cysteine-capped gold nanoparticles as a chiral selector. The chiral discrimination is based on a drug-induced nanoparticle diastereoselective aggregation mechanism that blocks ion transport through the nanochannel. We demonstrated that high S-Npx selectivity in both water and biological samples can be achieved. This simple method has potential applications as a general platform for the detection of chiral molecules. © 2016 American Chemical Society.
语种：
英文
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The macroscopic wettable surface: fabricated by calix[4]arene-based host-guest interaction and chiral discrimination of glucose (vol 52, pg 14416, 2016)
作者：
Sun, Yue;Mei, Yuxiao;Quan, Jiaxin;Xiao, Xuan;Zhang, Lin;...
期刊：
Chemical Communications ,2017年53(5):984-984 ISSN：1359-7345
通讯作者：
Tian, Demei
作者机构：
[Sun, Yue; Xiao, Xuan; Li, Haibing; Mei, Yuxiao; Zhang, Lin; Quan, Jiaxin; Tian, Demei] Cent China Normal Univ, Coll Chem, Key Lab Pesticide & Chem Biol, Minist Educ, Wuhan 430079, Peoples R China.
通讯机构：
[Tian, Demei] C;Cent China Normal Univ, Coll Chem, Key Lab Pesticide & Chem Biol, Minist Educ, Wuhan 430079, Peoples R China.
摘要：
Correction for 'The macroscopic wettable surface: fabricated by calix[4]arene-based host-guest interaction and chiral discrimination of glucose' by Yue Sun et al., Chem. Commun., 2016, 52, 14416-14418.
语种：
英文
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Chiral Selective Transport of Proteins by Cysteine-Enantiomer-Modified Nanopores
作者：
Zhang, Fan;Sun, Yue;Tian, Demei;Li, Haibing*
期刊：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION ,2017年56(25):7186-7190 ISSN：1433-7851
通讯作者：
Li, Haibing
作者机构：
[Sun, Yue; Li, Haibing; Zhang, Fan; Tian, Demei] Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol CCNU, Wuhan 430079, Peoples R China.
通讯机构：
[Li, Haibing] C;Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol CCNU, Wuhan 430079, Peoples R China.
关键词：
biomimetic nanopores;chiral selectivity;cysteine;nanopores;protein transport
摘要：
Chirality is an intriguing and intrinsic feature of life and is highly associated with many significant biological processes. However, whether it influences the translocation behavior of proteins remains unclear. Herein, based on biomimetic strategies, we made chiral nanopores modified with cysteine enantiomers, and studied the chirality gating effects on protein transport. The results show that protein is preferentially transported through nanopores modified with l-cysteine because of chiral interaction, indicating chirality strongly influences protein transport process. This study presents a new method for better understanding the role of chirality in selective protein transport processes and provides a convenient approach for studying protein chiral separation and targeted treatments.
语种：
英文
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A light-regulated host-guest-based nanochannel system inspired by channelrhodopsins protein
作者：
Sun, Yue;Ma, Junkai;Zhang, Fan;Zhu, Fei;Mei, Yuxiao;...
期刊：
Nature Communications ,2017年8(1):260 ISSN：2041-1723
通讯作者：
Li, Haibing
作者机构：
[Sun, Yue; Li, Haibing; Mei, Yuxiao; Zhu, Fei; Zhang, Fan; Liu, Lu; Tian, Demei] Cent China Normal Univ, Coll Chem, Key Lab Pesticide & Chem Biol CCNU, Minist Educ, Wuhan 430079, Hubei, Peoples R China.;[Ma, Junkai] Hubei Univ Med, Sch Pharm, Dept Chem, Hubei Key Lab Wudang Local Chinese Med Res, Shiyan 442000, Hubei, Peoples R China.
通讯机构：
[Li, Haibing] C;Cent China Normal Univ, Coll Chem, Key Lab Pesticide & Chem Biol CCNU, Minist Educ, Wuhan 430079, Hubei, Peoples R China.
摘要：
The light-controlled gating of ion transport across membranes is central to nature (e.g., in protein channels). Herein, inspired by channelrhodopsins, we introduce a facile non-covalent approach towards light-responsive biomimetic channelrhodopsin nanochannels using host-guest interactions between a negative pillararene host and a positive azobenzene guest. By switching between threading and dethreading states with alternating visible and UV light irradiation, the functional channels can be flexible to regulate the inner surface charge of the channels, which in turn was exploited to achieve different forms of ion transport, for instance, cation-selective transport and anion-selective transport. Additionally, the pillararene-Azobenzene-based nanochannel system could be used to construct a light-Activated valve for molecular transport. Given these promising results, we suggest that this system could not only provide a better understanding of some biological processes, but also be applied for drug delivery and various biotechnological applications. © 2017 The Author(s).
语种：
英文
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Temperature-Sensitive Artificial Channels through Pillar[5]arene-based Host–Guest Interactions
作者：
Wang, Rui;Sun, Yue* ;Zhang, Fan;Song, Miaomiao;Tian, Demei;...
期刊：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION ,2017年56(19):5294-5298 ISSN：1433-7851
通讯作者：
Sun, Yue;Li, Haibing
作者机构：
[Song, Miaomiao; Sun, Yue; Li, Haibing; Zhang, Fan; Tian, Demei; Wang, Rui; Sun, Y; Li, HB] Cent China Normal Univ, Key Lab Pesticide & Chem Biol CCNU, Minist Educ, Coll Chem, Wuhan 430079, Peoples R China.
通讯机构：
[Sun, Y; Li, HB] C;Cent China Normal Univ, Key Lab Pesticide & Chem Biol CCNU, Minist Educ, Coll Chem, Wuhan 430079, Peoples R China.
关键词：
biomimetic systems;current rectification;nanochannels;pillararenes;temperature sensitivity
摘要：
In living systems, temperature-sensitive ion channels play a vital role in numerous cellular processes and can be controlled by biological ion channels in response to specific temperature stimuli. Facile pillar[5]arene-based host–guest interactions are introduced into a nanochannel pattern for constructing a temperature-sensitive artificial channel. Ion transport was switched from cations to anions by controlling the extent of the host bound to the guest with temperature stimuli. This efect is mainly due to the changing of the inner surface charge and wettability of the nanochannel during the process. This study paves a new way for better understanding the mechanism of temperature-sensitive properties and shows great promise for biomedical research. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim
语种：
英文
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Chiral Responsive Liquid Quantum Dots
作者：
Zhang, Jin;Ma, Junkai* ;Shi, Fangdan;Tian, Demei;Li, Haibing*
期刊：
Advanced Materials ,2017年29(32):1700296- ISSN：0935-9648
通讯作者：
Ma, Junkai;Li, Haibing
作者机构：
[Zhang, Jin; Ma, Junkai; Li, Haibing; Shi, Fangdan; Ma, JK; Li, HB; Tian, Demei] Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol CCNU, Wuhan 430079, Hubei, Peoples R China.;[Ma, Junkai] Hubei Univ Med, Sch Pharm, Dept Chem, Hubei Key Lab Wudang Local Chinese Med Res, Shiyan 442000, Hubei, Peoples R China.
通讯机构：
[Ma, JK; Li, HB] C;[Ma, Junkai] H;Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol CCNU, Wuhan 430079, Hubei, Peoples R China.;Hubei Univ Med, Sch Pharm, Dept Chem, Hubei Key Lab Wudang Local Chinese Med Res, Shiyan 442000, Hubei, Peoples R China.
关键词：
chiral responsiveness;chiral separation;fluidic behaviors;liquid quantum dots
摘要：
How to convert the weak chiral-interaction into the macroscopic properties of materials remains a huge challenge. Here, this study develops highly fluorescent, selectively chiral-responsive liquid quantum dots (liquid QDs) based on the hydrophobic interaction between the chiral chains and the oleic acid-stabilized QDs, which have been designated as (S)-1810-QDs. The fluorescence spectrum and liquidity of thermal control demonstrate the fluorescence properties and the fluidic behavior of (S)-1810-QDs in the solvent-free state. Especially, (S)-1810-QDs exhibit a highly chiral-selective response toward (1R, 2S)-2-amino-1,2-diphenyl ethanol. It is anticipated that this study will facilitate the construction of smart chiral fluidic sensors. More importantly, (S)-1810-QDs can become an attractive material for chiral separation.
语种：
英文
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Inside Back Cover: Protein Adsorption Switch Constructed by a Pillar[5]arene-Based Host-Guest Interaction (Chem. Eur. J. 3/2016)
作者：
Xuan Xiao;Guanrong Nie;Xiaoyan Zhang;Demei Tian;Prof. Haibing Li*
期刊：
CHEMISTRY-A EUROPEAN JOURNAL ,2016年22(3):1179-1179 ISSN：0947-6539
通讯作者：
Prof. Haibing Li
作者机构：
[Xuan Xiao; Guanrong Nie; Xiaoyan Zhang; Demei Tian; Prof. Haibing Li] Key Laboratory of Pesticide and Chemical Biology (CCNU), Ministry of Education, College of Chemistry, Central China Normal University, Wuhan, 430079 P.R. China
通讯机构：
[Prof. Haibing Li] K;Key Laboratory of Pesticide and Chemical Biology (CCNU), Ministry of Education, College of Chemistry, Central China Normal University, Wuhan, 430079 P.R. China
关键词：
bovine serum albumin;host–guest systems;pH reversible switch;pillar[5]arene;proteins
摘要：
The interfacial properties of solid substrates are of importance for protein adsorption. A reversible protein adsorption switch based on the host–guest interaction of the butoxy pillar[5]arene and adipic acid is reported. Through the detection of the contact angle, AFM and luminoscope measurements on the silicon substrate, the intelligent protein switch was found to exhibit excellent adsorptivity for BSA and switch performance by pH regulation. This system holds the possibility for wide applications in the production of new biosensors, immunological tests, and drug delivery. More information can be found in the Full Paper by H. Li et al. on page 941 ff.
语种：
英文
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Self-assembly of 1,3-alternate calix[4]arene carboxyl acids-modified silver nanoparticles for colorimetric Cu2+ sensing
作者：
Nsengiyuma, Gilbert;Hu, Ren;Li, Jing;Li, Haibing;Tian, Demei*
期刊：
Sensors and Actuators B-Chemical ,2016年236:675-681 ISSN：0925-4005
通讯作者：
Tian, Demei
作者机构：
[Li, Haibing; Hu, Ren; Li, Jing; Nsengiyuma, Gilbert; Tian, Demei] Cent China Normal Univ, Coll Chem, Key Lab Pesticide & Chem Biol CCNU, Minist Educ, Wuhan 430079, Peoples R China.
通讯机构：
[Tian, Demei] C;Cent China Normal Univ, Coll Chem, Key Lab Pesticide & Chem Biol CCNU, Minist Educ, Wuhan 430079, Peoples R China.
关键词：
1,3-alternate calix[4]arene;Silver nanoparticles;Colorimetric sensor;Self-assembly
摘要：
In this study, a novel colorimetric sensor based on 1,3-alternate calix[4]arene-modified silver nanoparticles (Ag NPs) was synthesized. The functionalized Ag NPs were characterized by Transmission Electron Microscopy (TEM) and Infrared Spectroscopy (IR). It was observed that the Ag NPs synthesized had a high selectivity for Cu<sup>2+</sup>ions with the detection limit of 2.5 ×10<sup>-6</sup>M. Based on the findings in this research, the 1,3-alternate calix[4]arene-modified Ag NPs was found to be useful for colorimetric detection of Cu<sup>2+</sup>in solution. Moreover, the Ag NPs continued to grow and larger three-dimensional aggregates were formed with increasing concentration of Cu<sup>2+</sup>. ©2016 Elsevier B.V. All rights reserved.
语种：
英文
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Zn2+ and EDTA Cooperative Switchable Nanofluidic Diode Based on Asymmetric Modification of Single Nanochannel
作者：
Sun, Yao;Zhang, Fan;Sun, Zhongyue;Song, Miaomiao;Tian, Demei;...
期刊：
CHEMISTRY-A EUROPEAN JOURNAL ,2016年22(13):4355-4358 ISSN：0947-6539
通讯作者：
Li, Haibing
作者机构：
[Song, Miaomiao; Li, Haibing; Sun, Zhongyue; Sun, Yao; Zhang, Fan; Tian, Demei] Cent China Normal Univ, Coll Chem, Minist Educ, Dept Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China.
通讯机构：
[Li, Haibing] C;Cent China Normal Univ, Coll Chem, Minist Educ, Dept Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China.
关键词：
biomimetic synthesis;nanochannels;nanofluidic diodes;nanostructures;Schiff bases
摘要：
Design and fabrication of smart switchable nanofluidic diodes remains a challenge in the life and materials sciences. Here, we present the first example of a novel Zn2+/EDTA switchable nanofluidic diode system based on the control of one-side of the modified hourglass-shaped nanochannel with salicylaldehyde Schiff base (SASB). The nanofluidic diode can be turned on in the response of Zn2+ and turned off in response to EDTA solution with good reversibility and recyclability. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
语种：
英文
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The macroscopic wettable surface: fabricated by calix[4]arene-based host-guest interaction and chiral discrimination of glucose
作者：
Sun, Yue;Mei, Yuxiao;Quan, Jiaxin;Xiao, Xuan;Zhang, Lin;...
期刊：
Chemical Communications ,2016年52(100):14416-14418 ISSN：1359-7345
通讯作者：
Tian, Demei
作者机构：
[Sun, Yue; Xiao, Xuan; Li, Haibing; Mei, Yuxiao; Zhang, Lin; Quan, Jiaxin; Tian, Demei] Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol CCNU, Wuhan 430079, Peoples R China.
通讯机构：
[Tian, Demei] C;Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol CCNU, Wuhan 430079, Peoples R China.
摘要：
Herein, we reported a new strategy based on self-assembly chemistry for chiral discrimination of glucose on a new S-mandelic acid-appended calix[4]arene (S-MC4) modified nanostructure, which exhibits macroscopic chiral preference for d-glucose via contact angle measurements (CA). The proposed macroscopic chiral device displays rapidly remarkable specificity and is convenient to use, which should be suitable for diagnostic purposes, nanomedical applications, etc. © The Royal Society of Chemistry.
语种：
英文
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手性柱芳烃的合成及其对葡萄糖对映体区分
作者：
孙跃;田德美;李海兵
作者机构：
[孙跃; 田德美; 李海兵] 华中师范大学化学学院农药与化学生物学教育部重点实验室
会议名称：
全国第十八届大环化学暨第十届超分子化学学术讨论会
会议时间：
2016-08-25
会议地点：
中国湖南长沙
关键词：
手性;葡萄糖;仿生纳米通道
摘要：
<正>葡萄糖的对映体区分在生命过程的细胞识别和调控中扮演着重要的角色,对其手性识别的研究将极大地有助于糖类参与生理和病理过程的研究。然而,构建一个简单且有效的人工纳米器件来模拟生物体中葡萄糖的对映体区分仍然是一个挑战性的工作。因此,基于仿生的策略,我们构建了基于手性柱芳烃的光控仿生通道,通过调控手性柱芳烃的脱落与组装实现
语种：
中文
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Macroscopic switches constructed through host-guest chemistry
作者：
Sun, Yue;Ma, Junkai;Tian, Demei;Li, Haibing
期刊：
Chemical Communications ,2016年52(25):4602-4612 ISSN：1359-7345
通讯作者：
Li, HB
作者机构：
[Sun, Yue; Ma, Junkai; Tian, Demei; Li, Haibing] Cent China Normal Univ, Coll Chem, Key Lab Pesticide & Chem Biol CCNU, Minist Educ, Wuhan 430079, Peoples R China.
通讯机构：
[Li, HB ] ;Cent China Normal Univ, Coll Chem, Key Lab Pesticide & Chem Biol CCNU, Minist Educ, Wuhan 430079, Peoples R China.
摘要：
Molecular switch systems, having been extensively studied in the solution phase, have the ability to perform with good controllability and rapid-responsiveness, making them ideally suited for the design of molecular devices for drug delivery, and information or sensing functions. Inspired by a wide range of objects with visual changes, like Mimosa pudica towards external stimuli, in order to understand molecular switches well, they must be interfaced with the macroscopic world so that they can be directly realized by visual detectable changes even observed by the naked eye. This can be critical for fabricating intelligent microfluidics and laboratory-on-chip devices, that may have wide applications in the fields of biology and materials science. But to realize this objective, especially for fabricating macroscopic surface switches, unveiling host-guest weak interactions to achieve visual phenomena is still the greatest thrill. Thankfully, surface contact angles provide us with a wonderful method to further investigate the microscopic origin of the macroscopic changes. Therefore, interfacial modification becomes a paramount process. Macrocyclic compounds, encompassing an innovative concept to deal with reversible noncovalent interactions between macrocyclic hosts and suitable guests, are good candidates for surface functionalization. In this feature article, we discuss recent developments in macroscopic contact angle switches formed by different macrocyclic hosts and highlight the properties of these new functional surfaces and their potential applications. © The Royal Society of Chemistry 2016.
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英文
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Protein Adsorption Switch Constructed by a Pillar[5]arene-Based Host-Guest Interaction
作者：
Xiao, Xuan;Nie, Guanrong;Zhang, Xiaoyan;Tian, Demei;Li, Haibing*
期刊：
CHEMISTRY-A EUROPEAN JOURNAL ,2016年22(3):941-945 ISSN：0947-6539
通讯作者：
Li, Haibing
作者机构：
[Xiao, Xuan; Li, Haibing; Nie, Guanrong; Zhang, Xiaoyan; Tian, Demei] Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol CCNU, Wuhan 430079, Peoples R China.
通讯机构：
[Li, Haibing] C;Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol CCNU, Wuhan 430079, Peoples R China.
关键词：
bovine serum albumin;host-guest systems;pH reversible switch;pillar[5]arene;proteins
摘要：
The interfacial properties of solid substrates are of importance for protein adsorption. Herein, we report a reversible protein adsorption switch based on the host-guest interaction of the butoxy pillar[5]arene and adipic acid. By the detector of the contact angle (CA), atomic force microscopy (AFM), and luminoscope on the silicon substrate, the intelligent protein switch exhibits excellent adsorptivity for BSA and switch performance by pH regulation. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
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英文
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The synthesis of pillar[5]arene functionalized graphene as a fluorescent probe for paraquat in living cells and mice
作者：
Mao, Xiaowei;Liu, Ting;Bi, Jiahai;Luo, Li;Tian, Demei;...
期刊：
Chemical Communications ,2016年52(23):4385-4388 ISSN：1359-7345
通讯作者：
Li, Haibing
作者机构：
[Luo, Li; Li, Haibing; Mao, Xiaowei; Bi, Jiahai; Tian, Demei; Liu, Ting] Cent China Normal Univ, Coll Chem, Key Lab Pesticide & Chem Biol CCNU, Minist Educ, Wuhan 430079, Peoples R China.
通讯机构：
[Li, Haibing] C;Cent China Normal Univ, Coll Chem, Key Lab Pesticide & Chem Biol CCNU, Minist Educ, Wuhan 430079, Peoples R China.
摘要：
As complex organisms vary in vivo, it remains a challenging task to get fluorescence 'turn on' imaging for special targets. To address this task, we have adopted a new strategy of inducing pillararene based host-guest interactions onto biocompatible graphene. By means of fluorescence competition displacement, hydrazino-pillar[5]arene modified graphene has been synthesized and provided as a 'turn on' probe for paraquat through monitoring of the fluorescence signal both in living cells and mice.
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英文
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