期刊：
Chemical Communications,2021年57(61):7480-7492 ISSN：1359-7345
通讯作者：
Liang, Feng(feng_liang@whu.edu.cn)
作者机构：
[Cheng, Ming; Xu, Weiwei; Li, Haibing; Dhinakaran, Manivannan Kalavathi; Zhang, Siyun] Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol CCNU, Wuhan 430079, Peoples R China.;[Liang, Feng; Wu, Qifa; Liu, Zhuo] Wuhan Univ Sci & Technol, Sch Chem & Chem Engn, Coal Convers & New Carbon Mat Hubei Key Lab, State Key Lab Refractories & Met, Wuhan 430081, Peoples R China.;[Kovaleva, Elena G.] Ural Fed Univ, Dept Technol Organ Synth, Mira St 28, Ekaterinburg 620002, Russia.
通讯机构：
[Feng Liang] T;[Elena G. Kovaleva] D;[Haibing Li] K;The State Key Laboratory of Refractories and Metallurgy, Coal Conversion and New Carbon Materials Hubei Key Laboratory, School of Chemistry & Chemical Engineering, Wuhan University of Science and Technology, Wuhan 430081, P. R. China<&wdkj&>Department of Technology for Organic Synthesis, Ural Federal University, Mira Street, 28, 620002 Yekaterinburg, Russia<&wdkj&>Key Laboratory of Pesticide and Chemical Biology (CCNU), Ministry of Education, College of Chemistry, Central China Normal University, Wuhan, P. R. China
摘要：
Chiral discrimination has gained much focus in supramolecular chemistry, since it is one of the fundamental processes in biological systems, enantiomeric separation and biochemical sensors. Though most of the biochemical processes can routinely recognize biological enantiomers, enantioselective identification of chiral molecules in artificial systems is currently one of the challenging topics in the field of chiral discrimination. Inaccuracy, low separation efficiency and expensive instrumentation were considered typical problems in artificial systems. Recently, chiral recognition on the interfaces has been widely used in the fields of electrochemical detection and biochemical sensing. For the moment, a series of macrocyclic host functionalized interfaces have been developed for use as chiral catalysts or for enantiomeric separation. Here, we have briefly exposited the most recent advances in the fabrication of supramolecular functionalized interfaces and their application for chiral recognition.
通讯机构：
[Haibing Li] K;Key Laboratory of Pesticide and Chemical Biology (CCNU), Ministry of Education, College of Chemistry, Central China Normal University, Wuhan 430079, P. R. China
摘要：
Inspired by the nuclear pore complex (NPC), herein we have established a biomimetic high-flux protein delivery system via the ingenious introduction of pillar[5]arene-based host–guest system into one side of artificial hour-glass shaped nanochannel. With a transport flux of 660 lysozymes per minute, the system provides efficient high-flux protein transport at a rate which is significantly higher than that of an unmodified nanochannel and conventional bilateral symmetrical modified nanochannels. In view of these promising results, the use of artificial nanochannel to improve protein transport not only presents a new potential chemical model for biological research and better understanding of protein transport behavior in the living systems, but also provides a high-flux protein transporter device, which may have applications in the design of protein drug release systems, protein separation systems and microfluidics in the near future.
作者机构：
[Sun, Kunpeng; Zhang, Jin] Chinese Acad Sci, Natl Engn Res Ctr Fine Petrochem Intermediates, Lanzhou Inst Chem Phys, Lanzhou 730000, Peoples R China.;[Zhang, Jin; Li, Haibing; Gu, Yulin; Yang, Yuxia] Cent China Normal Univ, Coll Chem, Key Lab Pesticide & Chem Biol CCNU, Minist Educ, Wuhan 430079, Peoples R China.;[Lucas, Rachel A.] Univ Calif Irvine, Dept Phys & Astron, Irvine, CA 92697 USA.
通讯机构：
[Kunpeng Sun] N;[Haibing Li] K;National Engineering Research Center for Fine Petrochemical Intermediates, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou730000, P. R. China<&wdkj&>Key Laboratory of Pesticide and Chemical Biology (CCNU), Ministry of Education, College of Chemistry, Central China Normal University, Wuhan 430079, P. R. China
作者：
Xiaowei Mao;Ming Cheng;Linfeng Chen;Jing Cheng;Haibing Li
期刊：
ACS Applied Bio Materials,2021年4(9):6954–6961 ISSN：2576-6422
通讯作者：
Li, H.;Cheng, J.
作者机构：
[Xiaowei Mao] Hubei Key Laboratory of Environmental and Health Effects of Persistent Toxic Substances, Institute of Environment and Health, Jianghan University, Wuhan 430056, P. R. China;[Ming Cheng; Linfeng Chen; Jing Cheng; Haibing Li] Key Laboratory of Pesticide and Chemical Biology (CCNU), Ministry of Education, College of Chemistry, Central China Normal University, Wuhan 430079, P. R. China
通讯机构：
[Jing Cheng; Haibing Li] K;Key Laboratory of Pesticide and Chemical Biology (CCNU), Ministry of Education, College of Chemistry, Central China Normal University, Wuhan 430079, P. R. China
作者机构：
[Boussouar, Imene; Li, Haibing; Zhang, Siyun] Cent China Normal Univ, Coll Chem, Key Lab Pesticide & Chem Biol CCNU, Minist Educ, Wuhan 430079, Peoples R China.
通讯机构：
[Haibing Li] K;Key Laboratory of Pesticide and Chemical Biology (CCNU), Ministry of Education, College of Chemistry, Central China Normal University, Wuhan 430079, China
摘要：
Imitating the signal transduction and transmembrane transport co ntrolled by biological channels in the cell membra ne,artificial nanochannels with a similar capability of sensing and transport are constructed as bionic nanochannels.To accomplish selective sensing and transport of biological analyte（as "guest"）,the bionic nanochannels are modified with the artificial receptor（as "host"）,Based on selective recognition between host and guest,bionic nanochannels translate the stimulus of the guest to electrochemical signal as sensors,and further regulate the transmission of guest as transporters.Howeve r,throughout all kinds of guests,the selective sensing and transpo rt of ions and chiral molecules is a challenging problem.And throughout all hosts of ions and chiral molecules,the macrocyclic hosts with multisite of recognition show better selectivity,such as crown ethers,cyclodextrins,calixarenes,and pillararenes.In this article,we highlight recent advances in the macrocyclic host-based nanochannels for the selective sensing and transport of ionic and chiral guests,summarize the similarities and differences of different kinds of macrocyclic host-based nanochannels,and expect the research direction and application prospect.
通讯机构：
[Prof. Jing Cheng; Prof. Haibing Li] K;[Prof. Xiaowei Mao] H;[Prof. Feng Liang] T;Hubei Key Laboratory of Environmental and Health Effects of Persistent Toxic Substances, Institute of Environment and Health, Jianghan University, Wuhan, 430056 P. R. China<&wdkj&>Key Laboratory of Pesticide and Chemical Biology (CCNU), Ministry of Education, College of Chemistry, Central China Normal University, Wuhan, 430079 P. R. China<&wdkj&>The State Key Laboratory of Refractories and Metallurgy, School of Chemistry and Chemical Engineering, Wuhan University of Science and Technology, Wuhan, 430081 P. R. China
关键词：
alkynyl-calix[4]arene;Carbamate pesticides;dynamic contact-angle.;selective rolling
通讯机构：
[Shan Jin] K;[Xiao-Shun Zhou] Z;[Joshua Hihath] D;Key Laboratory of Pesticide and Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, Wuhan 430079, China<&wdkj&>Zhejiang Key Laboratory for Reactive Chemistry on Solid Surfaces, Institute of Physical Chemistry, Zhejiang Normal University, Jinhua, Zhejiang 321004, China<&wdkj&>Department of Electrical and Computer Engineering, University of California Davis, Davis, California 95616, United States
作者机构：
[Yue Sun] Hubei Key Laboratory of Catalysis and Materials Science, College of Chemistry and Material Sciences, South-Central University for Nationalities, Wuhan, 430074, China;Jiangxi Key Laboratory of Organic Chemistry, Jiangxi Science and Technology Normal University, Nanchang 330013, China;[Haibing Li] Key Laboratory of Pesticide and Chemical Biology (CCNU), Ministry of Education, College of Chemistry, Central China Normal University, Wuhan 430079, China;[Zhao Chen] Hubei Key Laboratory of Catalysis and Materials Science, College of Chemistry and Material Sciences, South-Central University for Nationalities, Wuhan, 430074, China<&wdkj&>Jiangxi Key Laboratory of Organic Chemistry, Jiangxi Science and Technology Normal University, Nanchang 330013, China
通讯机构：
[Yue Sun] H;[Haibing Li] K;Key Laboratory of Pesticide and Chemical Biology (CCNU), Ministry of Education, College of Chemistry, Central China Normal University, Wuhan 430079, China<&wdkj&>Hubei Key Laboratory of Catalysis and Materials Science, College of Chemistry and Material Sciences, South-Central University for Nationalities, Wuhan, 430074, China
作者机构：
[Cheng, Ming; Li, Haibing; Dhinakaran, Manivannan Kalavathi; Zhang, Siyun] Cent China Normal Univ CCNU, Coll Chem, Key Lab Pesticide & Chem Biol, Minist Educ, Wuhan 430079, Peoples R China.;[Sun, Yue] Tiangong Univ, Sch Chem, State Key Lab Separat Membrane & Membrane Proc, Tianjin 300387, Peoples R China.;[Sun, Yue] South Cent Univ Nationalities, Coll Chem & Mat Sci, Hubei Key Lab Catalysis & Mat Sci, Wuhan 430074, Peoples R China.
通讯机构：
[Yue Sun] S;[Haibing Li] K;Key Laboratory of Pesticide and Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University (CCNU), Wuhan, 430079, People’s Republic of China<&wdkj&>State Key Laboratory of Separation Membrane and Membrane Process, School of Chemistry, Tiangong University, Tianjin 300387, People’s Republic of China<&wdkj&>Hubei Key Laboratory of Catalysis and Materials Science, College of Chemistry and Material Sciences, South-Central University for Nationalities, Wuhan 430074, People’s Republic of China
摘要：
Chirality is a fascinating and essential feature of life and highly associated with many significant pharmaceutical, chemical, and biological processes. The construction of chiral recognition platform is a hot research topic and challenging assignment. Herein, we report an electrochemical method by differential pulse voltammetry (DPV) for the enantioselective recognition of chiral drug propranolol (R/S-PPL) through a nanochannel platform based on the N-acetyl-L-cysteine functionalized pillar[5]arenes derivative NALC-P5 and the porous polycarbonate membrane. The chiral discrimination depends on the difference in the supramolecular host-guest interaction between the chiral NALC-P5 and the R/S-PPL. The transmission rate of the R/S-PPL can be regulated in the nanochannel and we can achieve the selective transport of the chiral drugs. This simple electrochemical technique has potential applications as a general platform for the recognition of chiral molecules.
摘要：
Photoresponsive azobenzene-cyclodextrin light-switches fabricated artificial film which can be used to regulate the transmission of glutathione (GSH) across the membrane will gain much significance due to the important role of GSH in various biological process. In this work, we used azobenzene-cyclodextrin complex as switchable unit to manipulate gating transport. Under the control of ultraviolet (UV 365 nm) and visible (Vis 430 nm) light, two states of "ON" and "OFF" transport of GSH can be realized by the switches. This study achieved controlled molecule transport through channels by taking GSH as the research object, providing a new theoretical model for biological research and hold promise for future applications such as light-controlled drug transmission.
通讯机构：
[Haibing Li] K;Key Laboratory of Pesticide and Chemical Biology (CCNU), Ministry of Education, College of Chemistry, Central China Normal University, Wuhan 430079, P. R. China
摘要：
The spreading of pesticide droplets on the surface of superhydrophobic plants is an important process, which can prevent the inadequate retention such as bouncing, splashing, and drifting, thereby improving the efficiency of pesticide utilization and reducing soil and groundwater pollution. Herein, we report an approach to fabricate a supramolecular amphiphilic system that significantly contributes to this issue. The hydrophilic amino-pillar[5]arene was synthesized, which could form vesicles with the hydrophobic long-chain guest. This host-guest complex decreased the surface tension, which greatly promotes the spreading of droplets. This study provides a new strategy for prolonging pesticide retention and reducing pesticide loss.
作者机构：
[Cheng, Shi-Qi; Sun, Yue; Qin, Si-Yong; Rong, Yu] South Cent Univ Nationalities, Coll Chem & Mat Sci, Hubei Key Lab Catalysis & Mat Sci, Wuhan 430074, Peoples R China.;[Liu, Xue-Qing; Han, Zhi-Liang] Jianghan Univ, Key Lab Optoelect Chem Mat & Devices, Minist Educ, Wuhan 430056, Peoples R China.;[Li, Haibing] Cent China Normal Univ, Coll Chem, Key Lab Pesticide & Chem Biol CCNU, Minist Educ, Wuhan 430079, Peoples R China.
通讯机构：
[Si-Yong Qin; Yue Sun] H;Hubei Key Laboratory of Catalysis and Materials Science, College of Chemistry and Material Sciences, South-Central University for Nationalities, Wuhan 430074, P.R. China
期刊：
ACS Applied Bio Materials,2020年3(2):1226-1232 ISSN：2576-6422
通讯作者：
Sun, Kunpeng(sunkp@licp.cas.cn)
作者机构：
[Mei, Yuxiao; Quan, Jiaxin; Gu, Yulin; Yang, Yuxia; Sun, Kunpeng] National Engineering Research Center for Fine Petrochemical Intermediates, Lanzhou Institute of Chemical Physics, Chinese Academic Sciences, Lanzhou;730000, China;[Huang, Jinmei; Li, Haibing] Key Laboratory of Pesticide and Chemical Biology (CCNU), Ministry of Education, College of Chemistry, Central China Normal University, Wuhan;430079, China;[Mei, Yuxiao; Quan, Jiaxin] 730000, China<&wdkj&>Key Laboratory of Pesticide and Chemical Biology (CCNU), Ministry of Education, College of Chemistry, Central China Normal University, Wuhan
通讯机构：
[Kunpeng Sun] N;[Haibing Li] K;Key Laboratory of Pesticide and Chemical Biology (CCNU), Ministry of Education, College of Chemistry, Central China Normal University, Wuhan, 430079, P. R. China<&wdkj&>National Engineering Research Center for Fine Petrochemical Intermediates, Lanzhou Institute of Chemical Physics, Chinese Academic Sciences, Lanzhou, 730000, P. R. China
